Results 151 to 160 of about 43,074 (261)

Production of graphene in solution by unzipping of carbon nanotubes [PDF]

, 2011
Chemical modification of the outer graphene layer of carbon nanotubes is an approach increasingly used, mainly to overcome the problem of interfacial bonding with different materials.
Costa, Florinda, Cunha, E. M., Fernandes, António J., Oliveira, Elisabete, Paiva, M. C.   +4 more
core  

Expanding the Chemical Space of Sugar Frameworks by Quaternization of the Anomeric Carbon Atom

European Journal of Organic Chemistry, Volume 28, Issue 37, October 11, 2025.
Novel C,C and C,N bifunctional fucosides are stereoselectively obtained starting from a common anomeric bromide intermediate. The developed methodology expands the chemical space at the anomeric position of fucose and supports future applications in glycomimetics design.
Sarah Mazzotta, Jacopo Gori, Gianluca Cavazzoli, Sara Sattin, Giovanni Macetti, Anna Bernardi   +5 more
wiley   +1 more source

Mechanochemische Methoden mit Anwendung in der Late‐Stage Modifizierung Pharmazeutisch Wirksamer Verbindungen

Angewandte Chemie, Volume 137, Issue 41, October 6, 2025.
Dieser Review diskutiert mechanochemische Strategien zur späten Modifizierung bioaktiver Wirkstoffe und bietet zugleich eine wertvolle Übersicht zur Auswahl geeigneter Substrate, um das pharmazeutische Potenzial neuer und bestehender (mechano)chemischer Verfahren zu evaluieren.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Synthesis with Perfect Atom Economy: Generation of Furan Derivatives by 1,3-Dipolar Cycloaddition of Acetylenedicarboxylates at Cyclooctynes

Molecules, 2014
Cyclooctyne and cycloocten-5-yne undergo, at room temperature, a 1,3-dipolar cycloaddition with dialkyl acetylenedicarboxylates 1a,b to generate furan-derived short-lived intermediates 2, which can be trapped by two additional equivalents of 1a,b or ...
Klaus Banert, Sandra Bochmann, Andreas Ihle, Oliver Plefka, Florian Taubert, Tina Walther, Marcus Korb, Tobias Rüffer, Heinrich Lang   +8 more
doaj   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Synthesis of new triazole-based trifluoromethyl scaffolds

Beilstein Journal of Organic Chemistry, 2008
Trifluoromethyl propargylamines react with various azide derivatives to afford 1,4-disubstituted 1,2,3-triazoles through a Huisgen 1,3-dipolar cycloaddition. The reaction is catalyzed by a Cu(I) species in acetonitrile, and the corresponding products are
Michela Martinelli, Thierry Milcent, Sandrine Ongeri, Benoit Crousse   +3 more
doaj   +1 more source

Engineering Photolabile Cyclopentane‐Fused Coumarins: From One‐Pot Synthesis to Mechanistic Study for Visible Light‐Triggered Photolysis

Chemistry – An Asian Journal, Volume 20, Issue 19, October 3, 2025.
Cyclopentane fusion in coumarin photocages transforms their behavior from rapid SN1‐mediated release (minutes) to a slower elimination pathway (hours), accompanied by dramatic spectral changes upon photolysis, providing complementary tools for controlled‐release applications requiring different payload delivery rates.
Jau‐Tien Lin, Hsuan‐Yu Lin, Tai‐Chung Lo, Chih‐Ling Lin, Yi‐Hsien Li, Wei‐Hao Wu, Ting‐Yi Hsieh, Shun‐Yuan Luo, Chih‐Chien Chu   +8 more
wiley   +1 more source

Cyaphide-Azide 1,3-Dipolar Cycloaddition Reactions: Scope and Applicability. [PDF]

Chemistry, 2023
Yang ES, Mapp A, Taylor A, Beer PD, Goicoechea JM.   +4 more
europepmc   +1 more source

Synthesis of some isoxazoline, isoxazole and pyrazole carboxylic acids as the precursors of new 1,2-diacyl-1-alkylhydrazines [PDF]

, 2013
A number of isoxazoline, isoxazole and pyrazole carboxylic acids or their esters has been synthesized via the 1,3-dipolar cycloaddition of corresponding nitrile oxides or diazomethane to unsaturated dipolarophiles.
Antonevich, I. P., Katok, Ya. M.
core  

Decarboxylative 1,3-dipolar cycloaddition of amino acids for the synthesis of heterocyclic compounds. [PDF]

Beilstein J Org Chem, 2023
Zhang X, Ma X, Zhang W.
europepmc   +1 more source