Results 91 to 100 of about 27,886 (261)
The Azidofunctionalization of Alkenes
ChemistryEurope, EarlyView.The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley +1 more source
Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(II) and copper(II) complex [PDF]
, 2017 A novel catalytic system based on covalently modified DNA is described. This catalyst promotes 1,3-dipolar reactions between azomethine ylides and maleimides.
Aboudzadeh, Ali +9 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2017 Trimethylsilyldiazomethane (TMS-CHN2) reacts readily with hetaryl thioketones to give sterically crowded 2-trimethylsilyl-4,4,5,5-tetrahetaryl-1,3-dithiolanes with complete regioselectivity at −75 °C as well as at rt.
Grzegorz Mlostoń +3 more
doaj +1 more source
ChemistryOpen, 2020 1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola +2 more
doaj +1 more source
5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
Frontiers in Chemistry, 2020 Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans +3 more
doaj +1 more source
Bioorthogonal Click‐to‐Release of Branched Pro‐Fluorophores
Chemistry – A European Journal, EarlyView.Alkene‐azide click‐to‐release branched prodrugs can amplify the amount of cargo activated. However, balance between the “click” and “release” steps is essential. Branched pro‐fluorophores provided the fastest‐to‐date click reaction of aryl azides and TCOs. The second branched core enabled the self‐immolation, releasing higher levels of fluorophore than
Thomasin Brind +5 more
wiley +1 more source
Cycloadditions in mixed aqueous solvents: the role of the water concentration [PDF]
, 2005 We examined the kinetics of a series of cycloaddition reactions in mixtures of water with methanol, acetonitrile and poly(ethylene glycol) (MW 1000). The reactions include the Diels–Alder (DA) reaction between cyclopentadiene and N-n-butylmaleimide or ...
Abraham +66 more
core +3 more sources
Chemistry – A European Journal, EarlyView.From fleeting intermediates to well‐defined molecular structures, carbenes (neutral divalent carbon) remind us that the most reactive ideas often make a large impact. Despite their wide‐ranging applications, the direct characterization of these reactive species remains a persistent experimental challenge.
Bethany Sawyer +2 more
wiley +1 more source
CHIMIA, 1992 Adducts obtained by 1,3-dipolar cycloadditions to 2,3-dihydroisothiazol-3-one 1,1-dioxides are inclined to undergo a cheletropic process, by which the newly formed heterocyclic part undergoes aromatization, while SO2 is extruded and an ...
Kaspar F. Burri
doaj +2 more sources
ChemMedChem, Accepted Article.Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore +5 more
wiley +1 more source