Results 111 to 120 of about 27,886 (261)
Asymmetric Lewis acid-catalyzed 1,3-dipolar cycloadditions [PDF]
, 2017 Highly tuned, one-point binding chiral iron and ruthenium complexes selectively coordinate and activate α,β-unsaturated aldehydes and ketones toward asymmetric catalytic Diels-Alder cycloaddition reactions.
Brinkmann, Yasmin +3 more
core
Copper Nanoparticles in Click Chemistry [PDF]
, 2015 Conspectus: The challenges of the 21st century demand scientific and technological achievements that must be developed under sustainable and environmentally benign practices.
Alonso, Francisco +2 more
core +2 more sources
Enantioselective 1,3-Dipolar Cycloadditions of α-Methylene Lactams to Construct Spirocycles. [PDF]
Org Lett, 2023 Nishiura Y +3 more
europepmc +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra +3 more
wiley +1 more source
Synthesis of 1,2,3-Triazole 5-Chloroisatin Derivatives via Copper-Catalyzed 1,3-Dipolar Cycloaddition Reactions [PDF]
, 2017 A facile and simple protocol for the ‘Click\u27 cycloaddition of organic azides with N-propargylchloroisatine catalyzed by CuI, produces in good yields novel of 1,4-disubstituted 1,2,3-triazoles were obtained.
Rodi, Y. K. (Y) +3 more
core +1 more source
ChemistryOpen, EarlyView.Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas +4 more
wiley +1 more source
Metal Acetylides in Cycloaddition Reactions [PDF]
, 2017 This review highlights recent advances in the synthesis of (hetero)aromatic systems via cycloaddition reactions of alkynylmetals with dienes and dipoles.
Comas-Barceló, J., Harrity, J.P.A.
core +1 more source
Controlling Drug Release From Supramolecular Polymer Surfaces by a Click‐To‐Release Reaction
Journal of Polymer Science, EarlyView.We present a strategy combining reactive supramolecular additives with a covalent click‐to‐release reaction for localized drug delivery. A trans‐cyclooctene additive releases a cytotoxic drug upon tetrazine administration. Fluorescent monitoring confirms release, and cytotoxic tests show effective cancer cell death.
Maritza M. Rovers +6 more
wiley +1 more source
Syntheses of Isoxazoline-Based Amino Acids by Cycloaddition of Nitrile Oxides and Their Conversion into Highly Functionalized Bioactive Amino Acid Derivatives [PDF]
, 2012 The present account illustrates the syntheses of isoxazoline- based amino acids by the cycloaddition of 1,3-dipolar nitrile oxides to the C–C double bond of unsaturated amino acid derivatives, with focus on the regio- and stereoselectivities of the ...
Fülöp, Ferenc +2 more
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Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections
Small Science, EarlyView.This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton +3 more
wiley +1 more source