Results 51 to 60 of about 8,043 (225)

Cycloadditions in mixed aqueous solvents: the role of the water concentration [PDF]

, 2005
We examined the kinetics of a series of cycloaddition reactions in mixtures of water with methanol, acetonitrile and poly(ethylene glycol) (MW 1000). The reactions include the Diels–Alder (DA) reaction between cyclopentadiene and N-n-butylmaleimide or ...
Abraham, Abraham, Adjei, Alsehaibani, Asaad, Baozue, Biswas, Biswas, Bradsher, Breon, Brisset, Bustamante, Cargill, Cargill, Cativiela, Cativiela, Cativiela, Cativiela, Chaterjee, Cox, Cox, Das, Datta, Desimoni, Desimoni, Dubbs, Dutta, Escalera, Gajewski, Ganguly, Gharmaleki, Hefter, Huisgen, Huot, Kim, Kumar, Lara, Li, Li, Li, Lizhuang, Lizhuang, Lizhuang, Maitra, Manzo, Marcus, Martin, Meijer, Otto, Otto, Paruta, Pramanik, Rideout, Rispens, Rispens, Rispens, Romero, Sangwan, Shehatta, Shehatta, Shehatta, Stephen, Turner, Turro, Valsaraj, Wijnen, Yilin   +66 more
core   +3 more sources

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

A sequential multistep process for the fully mechanochemical, one-pot synthesis of the antiepileptic drug rufinamide

Green Chemistry Letters and Reviews, 2022
Mechanochemistry is a powerful tool to develop environmentally benign syntheses of active pharmaceutical ingredients. In this context, we report here the synthesis of the anti-epileptic agent rufinamide through a one-pot sequential multi-component ...
Jorge Gómez-Carpintero, Clara Cabrero, Juan Domingo Sánchez, Juan Francisco González, José Carlos Menéndez   +4 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

[4 + 2] Cycloadditions of diphenylketene with a highly substituted 1,3-diene [PDF]

, 1987
Diphenylketene (2) undergoes [4 + 2] cycloadditions with the s-cis fixed diene (1) to give the dihydropyran (3) and the cyclohexenone (4)
Heigl, Ulrich W., Mayr, Herbert
core   +1 more source

(SP,SP)-(–)-(E)-1,2-Bis(methylphenylphosphinoyl)ethene

Acta Crystallographica Section E, 2009
The title compound, C16H18O2P2, possesses two stereogenic P atoms and shows a distorted s–cis conformation of each O=P—C=C moiety. This has been suggested on the basis of the stereochemical result of 1,3-dipolar cycloadditions with ...
doaj   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

1,3-dipolar cycloadditions of aldehydes or Imines with carbonyl ylides generated from epoxides: Classical heating and microwave irradiation [PDF]

, 2007
International audienceCycloadditions of aldehydes with carbonyl ylides to give dioxolanes have been carried out without solvent under microwave irradiation. The reactions proceeded in similar yields and stereoselectivities, but in shorter reaction times,
Bazureau, Jean-Pierre, Bentabed-Ababsa, Ghenia, Derdour, Aicha, Hamelin, Jack., Mongin, Florence, Rahmouni, Mustapha   +5 more
core   +3 more sources

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

A Convenient, Safe, and Atom‐Economical Route to a Large Portfolio of Grubbs‐Type Catalysts for Olefin Metathesis via Four‐Coordinate Ruthenium Alkylidynes

Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.
It may seem counterintuitive to first target a ruthenium alkylidyne when Grubbs‐type ruthenium carbene complexes are the actual goal. In the end, however, this tactic pays valuable dividends in terms of practicality, atom economy, flexibility as well as safety: the new route provides ready access to a large assortment of catalysts for alkene metathesis
Mingxu Cui, Alois Fürstner
wiley   +2 more sources