Results 41 to 50 of about 416,337 (149)
Lewis Acid-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions of Diazoalkane: Chiral Ligand/Achiral Auxiliary Cooperative Chirality ...
Shuji Kanemasa (2513860) +1 more
core +1 more source
Bicyclo[1.1.0]butanes undergo a Lewis acid‐catalyzed formal (3 + 3) annulation with indolyl alcohols to furnish indole‐fused aza‐bicyclo[3.1.1]heptanes. Strain‐release‐driven C‐C bond formation, followed by C‐N bond formation via ring expansion, enables the rapid assembly of rigid, sp3‐rich bicyclic architectures under mild reaction conditions ...
Mainak Dey +4 more
wiley +1 more source
Per‐ethylene‐glycol (EG)‐functionalized resorcin[4]arenes containing 12, 16, and 20 EG groups namely compounds 1d, 1e, and 1f, respectively, were prepared and found to self‐assemble, in organic solvents, into hexameric capsules. These capsules are more dynamic than the ones prepared based on alkyl substituted resorcin[4]arenes.
Gangadhara Angajala +3 more
wiley +1 more source
Intramolecular 1,3-Dipolar Cycloadditions of Norbornadiene-Tethered Nitrile Oxides
Efficient routes to the synthesis of norbornadiene-tethered nitrile oxides have been developed, and their intramolecular 1,3-dipolar cycloadditions were studied.
Geoffrey K. Tranmer (2520547) +3 more
core +1 more source
This work describes the first example of a thermally stable α‐SF5 organometallic reagent, which allows for extensive downstream functionalization by allylation and acylation reactions under copper catalysis, as well as palladium‐catalyzed Negishi‐type cross‐coupling conditions up to 96% yield. In silico analysis shines initial light on the requirements
Lujie Xu, David Rombach
wiley +1 more source
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy +7 more
wiley +2 more sources
Photocatalysis‐Triggered Click Reactions and Applications
Photoclick chemistry offers broad applications ranging from materials science to bioconjugation, with precise spatiotemporal control over click reactions. Initially limited to UV activation, recent advances have extended photoclick processes to the visible and NIR regions thanks to the photocatalysis.
Margaux Walter +2 more
wiley +1 more source
Bromonitroalkanes in Organic Synthesis
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley +1 more source
Oxaziridines: Versatile Reagents in Modern Organic Synthesis
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra +2 more
wiley +1 more source
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara +5 more
wiley +1 more source

