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Iodocyclization of 1,4-dihydropyridines

Tetrahedron Letters, 1998
Abstract Iodine (or related species) addition to 1,4-dihydropyridines, with properly attached substituents at the nitrogen atom, leads to the corresponding 3-iodotetrahydropyridinium ions, which undergo an internal nucleophilic attack to furnish regio- and stereoselectively iodobi(poly)lteterocyclic ring systems in good yields.
Rodolfo Lavilla   +3 more
openaire   +1 more source

Glutathione-Coated Magnetic Nanoparticles for One-Pot Synthesis of 1,4-Dihydropyridine Derivatives

Polycyclic aromatic compounds (Print), 2019
A magnetic Fe3O4 supported glutathione catalyst was synthesized in a convenient and eco-friendly manner and characterized using FT-IR, XRD, TGA, TEM, VSM, EDX, and elemental analysis. This nano-organocatalyst exhibited excellent catalytic activity in the
B. Maleki   +3 more
semanticscholar   +1 more source

Novel fluorescent 1,4-dihydropyridines

Journal of the American Chemical Society, 1986
Etude de la reaction modele de formation d'α-alkyl alkyl-4 diformyl-3,5 dihydro-1,4 pyridineacetates-1 a partir de propanedial, d'alcanals et d'α ...
Vasu. Nair   +2 more
openaire   +1 more source

Molecular Studies on Novel Antitumor Bis 1,4-Dihydropyridine Derivatives Against Lung Carcinoma and their Limited Side Effects on Normal Melanocytes.

Anti-Cancer Agents in Medicinal Chemistry, 2019
BACKGROUND Cancer is a complex genetic disease which is characterized by an abnormal cell growth, invasion and spreading to other parts of the body. There are several factors that lead to cancer by causing DNA damage and the impairment of its repair ...
Magda F. Mohamed   +3 more
semanticscholar   +1 more source

Fluorine-containing 1,4-dihydropyridines

Journal of Fluorine Chemistry, 1996
Abstract A series of 1,4-dihydropyridines with fluorine-containing substituents of various electronic nature and lipophilicity, as synthesized in our Department, are considered and their biological activity as calcium channels modulators is discussed.
L.M. Yagupolskii   +3 more
openaire   +1 more source

1,4-Dihydropyridine: A Dependable Heterocyclic Ring with the Promising and the Most Anticipable Therapeutic Effects.

Mini-Reviews in Medical Chemistry, 2019
Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal chemistry. Among all of the heterocyclic scaffolds, 1,4-Dihydropyridine (1,4-DHP) is one of the most important heterocyclic rings that possess prominent therapeutic ...
A. Mishra, Ankit Bajpai, A. Rai
semanticscholar   +1 more source

Synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives via Hantzsch reaction using nicotinic acid as a green and reusable catalyst

Journal of Molecular Structure, 2019
A rapid, efficient and eco-friendly protocol has been developed for the preparation of various 1,4-dihydropyridine and polyhydroquinoline derivatives in the presence of nicotinic acid as a green and dual catalyst under solvent-free conditions.
J. Davarpanah   +2 more
semanticscholar   +1 more source

Efficient one-pot synthetic methods for the preparation of 3,4-dihydropyrimidinones and 1,4-dihydropyridine derivatives using BNPs@SiO2(CH2)3NHSO3H as a ligand and metal free acidic heterogeneous nano-catalyst

, 2020
Heterocyclic compounds with biological and pharmacological activates like 3,4-dihydropyrimidin-2-(1H)-ones and 1,4-dihydropyridines have attracted great interest. Boehmite nanoparticles functionalized with silylpropyl sulfamic acid (BNPs@SiO2(CH2)3NHSO3H)
Minoo Khodamorady   +2 more
semanticscholar   +1 more source

Synthesis of Bis‐1,4‐dihydropyridine Derivatives.

ChemInform, 2005
Abstract A series of bis‐1,4‐dihydropyridine derivatives were synthesized by the reaction of p‐phenylenedialdehyde or m‐phenylenedialdehyde and active methylene compounds.
Songlei Zhu   +7 more
openaire   +1 more source

Solid-state acidochromic properties of barbituric acid-based 1,4-dihydropyridine derivatives with multiple coloured emissions switching

Dyes and pigments, 2019
Solid-state acidochromic (SSAC) molecules often exhibit dual-coloured rather than multi-coloured stimuli-responsive properties. To obtain the molecule possessing a multi-coloured emission switching based on one specific solid-state of a single molecule ...
Mengzhu Wang   +8 more
semanticscholar   +1 more source

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