Results 151 to 160 of about 284,169 (292)
, 2013 Nervous system conditional knockout (cKO) of PGC-1α was mediated by crossing PGC-1αfl/fl mice with mice expressing cre recombinase driven by the nestin promoter. A.
Alisa T. Trinh (311418) +5 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
SDF-1α/CXCR4 induced CSCs migration via PI3K pathway.
, 2012 A.
Hang Wang (137566) +7 more
core +1 more source
, 2019 Additional file 1: Table S1. Phytochemical analysis of CRACE. Table S2. Primer sequences. Figure S1. CRACE was non-cytotoxic to a number of tested cells at tested doses.
Borah, Anuj +5 more
openaire +1 more source
, 2018 Sequences of the primers used in this study. (DOC 32Â kb)
Quan, Juan-Hua +7 more
openaire +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
PGC-1α mRNA levels in skeletal muscle, by RT-qPCR, after rotarod exercise.
, 2015 (A) Schematic diagram of PGC-1α isoforms examined in this study. PGC-1α-a is expressed from one promoter, whereas PGC-1α-b and PGC-1α-c are both expressed from the same promoter.
Shirley M. Taylor (751218) +3 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2016 The nuclear EF-1α alignment in fasta ...
Sereina Rutschmann (3201123) +7 more
core +1 more source