Results 181 to 190 of about 3,850 (205)

Occurrence of Orally Administered Mulberry 1-Deoxynojirimycin in Rat Plasma

Journal of Agricultural and Food Chemistry, 2007
1-deoxynojirimycin (DNJ), a potent glucosidase inhibitor, is a characteristic constituent of the mulberry leaf. Dietary mulberry DNJ may be beneficial for the suppression of abnormally high blood glucose levels, thereby preventing diabetes mellitus. Although there is considerable interest in the effects of mulberry DNJ, the intestinal absorption and ...
Kiyotaka, Nakagawa, Hiroyuki, Kubota, Toshiyuki, Kimura, Shinji, Yamashita, Tsuyoshi, Tsuzuki, Shinichi, Oikawa, Teruo, Miyazawa   +6 more
openaire   +2 more sources

Asymmetric syntheses of 1-deoxy-6-epicastanospermine andrhamno-1-deoxynojirimycin

Chirality, 1998
The concise and highly diastereoselective synthesis of the titles azasugars was accomplished using nonracemic bicyclic lactams. Chirality 10:88–90, 1998. © 1998 Wiley-Liss, Inc.
A I, Meyers, D A, Price
openaire   +2 more sources

Total synthesis of N-butyl-1-deoxynojirimycin

Journal of Carbohydrate Chemistry, 2016
N-Butyl-1-deoxynojirimycin (NB-DNJ) derived from imino sugar deoxynojirimycin (DNJ) has been approved for the treatment of Gaucher's disease.
Jiajia Wang, Yunyan Zhao, Wei Zhao, Peng Wang, Jing Li   +4 more
openaire   +1 more source

Inhibitory effect of novel 1-deoxynojirimycin derivatives on HIV-1 replication

AIDS, 1990
The effect of 11 derivatives of 1-deoxynojirimycin (DNM) on the replication of HIV-1 was studied. Compared with DNM, seven of them showed remarkable inhibition of HIV-1-induced syncytium formation at significantly low concentrations which were not cytotoxic.
H, Shimizu, H, Tsuchie, K, Yoshida, S, Morikawa, T, Tsuruoka, H, Yamamoto, H, Ushijima, T, Kitamura   +7 more
openaire   +2 more sources

The synthesis of 7-carbonyl homologues of 1-deoxynojirimycin

Tetrahedron Letters, 1994
Abstract A 3,4;5,6-di- O -isopropylidene salt derivative of 1-amino-1-deoxy-D-glucitol was transformed to N -Boc protected (5,6)-α,β-unsaturated 7-carbonyl compounds. Conversion to the title piperidine products proceeded via deprotection and intramolecular 1,4-addition of the amino group.
Amuri Kilonda, Frans Compernolle, Suzanne Toppet, Georges J. Hoornaert   +3 more
openaire   +1 more source

Synthesis of 1-Deoxynojirimycin and N-Butyl-1-deoxynojirimycin

Synthesis, 1999
Carlos R. R. Matos, Rosangela S. C. Lopes, Claudio C. Lopes   +2 more
openaire   +1 more source

A comprehensive review on the production, pharmacokinetics and health benefits of mulberry leaf iminosugars: Main focus on 1-deoxynojirimycin, d-fagomine, and 2-O-ɑ-d-galactopyranosyl-DNJ

Critical Reviews in Food Science and Nutrition, 2023
Soo Takasu, Kiyotaka Nakagawa
exaly  

1-Deoxynojirimycin and its Derivatives: A Mini Review of the Literature

Current Medicinal Chemistry, 2021
wang haijun, Shen Yin, Lei Zhao
exaly  

Synthesis of d-galacto-1-deoxynojirimycin (1,5-dideoxy-1,5-imino-d-galactitol) starting from 1-deoxynojirimycin

Carbohydrate Research, 1990
Fred-Robert Heiker, Alfred Matthias Schueller   +1 more
openaire   +1 more source

Total synthesis of (+)-nojirimycin and (+)-1-deoxynojirimycin

The Journal of Organic Chemistry, 1987
Hideo Iida, Naoki Yamazaki, Chihiro Kibayashi   +2 more
openaire   +1 more source