Results 221 to 230 of about 317,690 (321)

Clustering of Membrane Receptors: Insights from DNA Origami‐Based Approaches

open access: yesSmall, EarlyView.
Receptor clustering critically influences cell signaling, yet its precise regulation remains elusive. This review highlights how DNA origami structures serve as nanoscale tools to uncover receptor organization and provide new insights into signal transduction.
Carmen M. Domínguez   +1 more
wiley   +1 more source

Distinct mRNA expression profiles and miRNA regulators of the PI3K/AKT/mTOR pathway in breast cancer: insights into tumor progression and therapeutic targets. [PDF]

open access: yesFront Oncol
Sirek T   +10 more
europepmc   +1 more source

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

open access: yesSmall Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri   +11 more
wiley   +1 more source

Dynamics of hyperglycemia of patients treated with alpelisib: exploratory interim analysis of ITACA trial. [PDF]

open access: yesOncologist
Pancirov M   +8 more
europepmc   +1 more source

HIV induces activation of phosphatidylinositol 4‐kinase and mitogen‐activated protein kinase by interacting with T cell CD4 surface molecules

open access: yesEuropean Journal of Immunology, 1996
H. Schmid-Antomarchi   +6 more
semanticscholar   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

open access: yesVIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

Ergosterol-induced immune response in barley involves phosphorylation of phosphatidylinositol phosphate metabolic enzymes and activation of diterpene biosynthesis. [PDF]

open access: yesNew Phytol
Saake P   +11 more
europepmc   +1 more source

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