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Down‐regulation of aquaporin 9 gene transcription by 10‐hydroxy‐2‐decenoic acid: A major fatty acid in royal jelly

open access: yesDown‐regulation of aquaporin 9 gene transcription by 10‐hydroxy‐2‐decenoic acid: A major fatty acid in royal jelly
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10-Hydroxy-2-decenoic acid from Royal jelly: A potential medicine for RA

Journal of Ethnopharmacology, 2010
Rheumatoid arthritis synovial fibroblasts (RASFs) are known to produce matrix metalloproteinases (MMPs) and cause joint destruction. The purpose of this study is to develop a potential medicine for rheumatoid arthritis (RA).To this end, first, the MMPs inhibition factor was purified from an alkali-solubilized fraction of RJ (Apis mellifera) by C18 ...
Xin-Yu, Yang   +10 more
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Production of 10‐Hydroxy‐2‐decenoic Acid from Decanoic Acid via Whole‐Cell Catalysis in Engineered Escherichia coli

ChemSusChem, 2021
Abstract10‐Hydroxy‐2‐decenoic acid (10‐HDA) is a terminal hydroxylated medium‐chain α,β‐unsaturated carboxylic acid that performs various unique physiological activities and has a wide market value. Therefore, development of an environmentally friendly, safe, and high‐efficiency route to synthesize 10‐HDA is required.
Yan Li   +10 more
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Absence of 10-Hydroxy-2-Decenoic Acid (10-HDA) in Bee-Collected Pollen

1986
Much attention has been paid to the survival of bee-collected pollen in pellets as well as those sticking to body hairs. This interest stems from plant breeders concern to prevent contamination when using bees for pollination purposes in isolation cages on the one hand and, on the other hand, one would like to use bee-collected pollen to improve seed ...
Verhoef, H.C.M., Hoekstra, F.A.
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Comparative proteomic analysis provides insight into 10-hydroxy-2-decenoic acid biosynthesis in honey bee workers

Amino Acids, 2017
10-Hydroxy-2-decenoic acid (10-HDA) is the major compound produced from the mandibular glands (MGs) of honey bee workers. However, little information is available on the molecular mechanisms of 10-HDA biosynthesis. In our study, based on investigating the 10-HDA secretion pattern and the morphological characteristics of MGs from honey bee workers of ...
Xiao-Hui, Yang   +2 more
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Biosynthesis of 10-Hydroxy-2-Decenoic Acid in Escherichia coli

Metabolic Engineering
10-hydroxy-2-decenoic acid (10-HDA), a unique unsaturated fatty acid present in royal jelly, has attracted considerable interest due to its potential medical applications. However, its low concentration in royal jelly and complex conformational structure present challenges for large-scale production. In this study, we designed and constructed a de novo
Dan, He   +5 more
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ChemInform Abstract: SYNTHESIS OF 10‐HYDROXY‐2‐DECENOIC ACID (ROYAL JELLY ACID) FROM THE BUTADIENE TELOMER

Chemischer Informationsdienst, 1977
AbstractDer Äthylester (VIb) der Titelverbindung wird aus dem durch Kondensation von Acetessigsäureäthylester mit Butadien in Gegenwart von Pd‐acetat und Triphenylphosphin in 80%iger Ausbeute erhältlichen Ester (I) über die Stufen (II), (III), (IVa), (IVb), (V) und (VIa) dargestellt [zur Entfernung der Tetrahydropyranyl‐ Schutzgruppe wird (VIa) mit ...
J. TSUJI   +4 more
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10-Hydroxy-2-decenoic acid inhibiting the proliferation of fibroblast-like synoviocytes by PI3K–AKT pathway

International Immunopharmacology, 2015
To reveal the mechanism of 10H2DA inhibiting the proliferation of fibroblast-like synoviocytes (FLSs) of RA patients. Cell proliferation, HDAC activity and histone acetylation level of FLS cells treated with 10H2DA were detected by MTT assay, Colorimetric HDAC Activity Assay and Western-blot.
Jianguang, Wang   +11 more
openaire   +2 more sources

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