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10‐Hydroxy‐2‐decenoic acid prevents ultraviolet A‐induced damage and matrix metalloproteinases expression in human dermal fibroblasts

Journal of the European Academy of Dermatology and Venereology, 2012
AbstractBackground  10‐Hydroxy‐2‐decenoic acid (10‐HDA) is a major fatty acid component of royal jelly, which has been reported to have a variety of beneficial pharmacological characteristics. However, the effects of 10‐HDA on skin photoageing and its potential mechanism of action are unclear.Objective  We investigated the protective effects of 10‐HDA ...
Jinfen, Zheng   +6 more
openaire   +2 more sources

Engineering Compartmentalization and Cofactor Regulation for 10-Hydroxy-2-decenoic Acid Biosynthesis in Saccharomyces cerevisiae

Journal of Agricultural and Food Chemistry
10-Hydroxy-2-decenoic acid (10-HDA), a bioactive component of royal jelly, exhibits significant pharmacological value in various applications. To date, its biosynthesis has been reported exclusively in endotoxin-prone Escherichia coli, which limits its biomedical utility. In this study, we successfully engineered the Generally Recognized As Safe (GRAS)
ChunLi Su   +10 more
openaire   +2 more sources

HPLC determination of pkavalue of 10-hydroxy-2-decenoic acid

Journal of Liquid Chromatography & Related Technologies, 2018
The utilization of HPLC methods is very useful for the determination of some physicochemical characteristics of compounds.
T. Angelov, I. Hristov
openaire   +1 more source

Determination of 10-hydroxy-2-decenoic acid in products with royal jelly

2015
Matična mliječ je prirodni eliksir koji čuva zdravlje i vitalnost čovjeka. Od njezinih mnogobrojnih sastojaka izdvaja se 10-hidroksi-2-decenska kiselina (10-HDA), u prirodi prisutna samo u matičnoj mliječi. Ona ima važne biološke učinke od kojih se izdvajaju antibakterijsko, protuupalno i imunmodulatorsko djelovanje.
Lalić, Zdenka   +2 more
openaire  

Connective tissue growth factor, a regulator related with 10-hydroxy-2-decenoic acid down-regulate MMPs in rheumatoid arthritis

Rheumatology International, 2011
10-hydroxy-2-decenoic acid (10H2DA) is suggested to be a potential medication for rheumatoid arthritis (RA) by activation of matrix metalloproteinases (MMPs) via mitogen-activated protein kinase signaling pathways. The aim of the present work was to seek differentially expressed proteins in rheumatoid arthritis synovial fibroblasts (RASFs) treated with
Jian-guang, Wang   +11 more
openaire   +2 more sources

10-Hydroxy-2-decenoic acid-derived aldehydes attenuate anaphylactic hypothermia in vivo

PharmaNutrition, 2022
Akira Sato   +2 more
openaire   +1 more source

Effects of 10-hydroxy-2-decenoic acid on phagocytosis and cytokines production of peritoneal macrophages in vitro.

Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999
To study the effect of 10-hydroxy-2-decenoic acid (HDA) on the macrophages activity of rats in vitro.To measure the effects of HDA on phagocytosis, the production of antitumor cytokines tumor necrosis factor (TNF) and interleukin-1 (IL-1) in vitro.HDA 50, 100 mg.L-1 promoted phagocytic activity from 0.353 +/- 0.017 to 0.39 +/- 0.04 and 0.382 +/- 0.017 ...
G Y, Wang, Z B, Lin
openaire   +1 more source

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