Antitumor Effects and the Potential Mechanism of 10-HDA against SU-DHL-2 Cells [PDF]
Pharmaceuticals10-hydroxy-2-decenoic acid (10-HDA), which is a unique bioactive fatty acid of royal jelly synthesized by nurse bees for larvae and adult queen bees, is recognized for its dual utility in medicinal and nutritional applications.
Wenchao Yang, Yang Wenchao
exaly +6 more sources
Enhancing 10-HDA production of Escherichia coli by heterologous expression of MexHID transporter proteins [PDF]
Frontiers in Bioengineering and Biotechnology10-Hydroxy-2-decenoic acid (10-HDA) is a medium-chain α,β-unsaturated carboxylic acid that exists in royal jelly with terminal hydroxylation. It has a broad market value because of its antibacterial, anti-inflammatory, anti-tumor, anti-radiation, and ...
Ziting Xu +11 more
doaj +4 more sources
Dissecting the Molecular Mechanism of 10-HDA Biosynthesis: Role of Acyl-CoA Delta(11) Desaturase and Transcriptional Regulators in Honeybee Mandibular Glands [PDF]
Insects10-Hydroxy-2-decenoic acid (10-HDA), a major fatty acid (FA) component of royal jelly, is synthesized in the mandibular glands (MGs) of worker honeybees.
Yunchang Li +3 more
doaj +4 more sources
10-HDA, A Major Fatty Acid of Royal Jelly, Exhibits pH Dependent Growth-Inhibitory Activity Against Different Strains of Paenibacillus larvae [PDF]
Molecules, 2018 Paenibacillus larvae (P. larvae) is a bacterial pathogen causing American foulbrood (AFB), the most serious disease of honeybee larvae. The food of young larvae could play an important role in the resistance of larvae against AFB.
Mária Šedivá +5 more
doaj +5 more sources
10-Hydroxy-2-decenoic Acid Suppresses Colorectal Cancer Progression by Inhibiting Wnt/β-Catenin Signaling and Promoting Apoptosis [PDF]
FoodsColorectal cancer (CRC) remains a leading cause of cancer-related death worldwide, and advanced disease continues to show poor prognosis due to therapeutic limitations and drug resistance.
Yan Lin +9 more
doaj +2 more sources
Novel involvement of LMTK2 and EML6 in rheumatoid arthritis: potential biomarkers for disease activity and seronegative patients [PDF]
Frontiers in ImmunologyIntroductionRheumatoid arthritis (RA) is a chronic, multifactorial autoimmune disease characterized by symmetrical polyarthritis, joint pain, and swelling, which can lead to disability and premature death.
Hubert Kubis +3 more
doaj +2 more sources
Closed-Set Heterogeneous Domain Adaptation for IoT Intrusion Detection: An Anchor-Based Benchmark Across Single- and Multi-Source Transfer [PDF]
SensorsClosed-set heterogeneous domain adaptation (HDA) for Internet of Things (IoT) intrusion detection aims to transfer detection capabilities across environments that differ in devices, telemetry, feature schemas, attack implementations, label taxonomies ...
Mohammad Chizari +3 more
doaj +2 more sources
Frontiers in Microbiology, 2023 IntroductionThis study aimed to investigated the effects of 10-hydroxy-2-decenoic acid (10-HDA) on the growth performance, intestinal barrier, inflammatory response, oxidative stress, and gut microbiota of chickens challenged with lipopolysaccharide (LPS)
Lianquan Han +6 more
doaj +1 more source
Molecules, 2022 Persistent infections caused by Staphylococcus aureus biofilms pose a major threat to global public health. 10-Hydroxy-2-decenoic acid (10-HDA), a main fatty acid in royal jelly, has been shown to possess various biological activities.
Kuankuan Gao +5 more
doaj +1 more source
Frontiers in Nutrition, 2022 10-Hydroxydec-2-enoic acid (10-HDA), an unsaturated hydroxyl fatty acid from the natural food royal jelly, can protect against cell and tissue damage, yet the underlying mechanisms are still unexplored.
Pei Fan +10 more
doaj +1 more source