Results 41 to 50 of about 6,444 (145)

Epidemiology, characteristics and treatment of patients with relapsing remitting multiple sclerosis and incidence of high disease activity: Real world evidence based on German claims data.

PLoS ONE, 2020
BACKGROUND:Multiple Sclerosis (MS) is a chronic inflammatory, immune mediated disease of the central nervous system, with Relapsing Remitting MS (RRMS) being the most common type.
Christoph Ohlmeier, Holger Gothe, Judith Haas, Ulrike Osowski, Carina Weinhold, Sarah Blauwitz, Niklas Schmedt, Wolfgang Galetzka, Fabian Berkemeier, Björn Tackenberg, Martin Stangel   +10 more
doaj   +1 more source

Thermodynamic Hydricity of Small Borane Clusters and Polyhedral closo-Boranes

Molecules, 2020
Thermodynamic hydricity (HDAMeCN) determined as Gibbs free energy (ΔG°[H]−) of the H− detachment reaction in acetonitrile (MeCN) was assessed for 144 small borane clusters (up to 5 boron atoms), polyhedral closo-boranes dianions [BnHn]2−, and their ...
Igor E. Golub, Oleg A. Filippov, Vasilisa A. Kulikova, Natalia V. Belkova, Lina M. Epstein, Elena S. Shubina   +5 more
doaj   +1 more source

10-Hydroxy Decanoic Acid-Based Vesicles as a Novel Topical Delivery System: Would It Be a Better Platform Than Conventional Oleic Acid Ufasomes for Skin Cancer Treatment?

Pharmaceutics, 2023
10-hydroxy decanoic acid (HDA), a naturally derived fatty acid, was used for the preparation of novel fatty acid vesicles for comparison with oleic acid (OA) ufasomes. The vesicles were loaded with magnolol (Mag), a potential natural drug for skin cancer.
Bassant Atef, Rania A. H. Ishak, Sabry S. Badawy, Rihab Osman   +3 more
doaj   +1 more source

A comparative Study for determination of 10-HDA in various Indian Royal Jelly samples using HPLC, HPTLC, and LC-MS/MS Techniques

, 2022
Abstract Bees, Apis mellifera, are precious natural resources that produce a variety of health-promoting bioactive compounds. Since it is a bee-derived product, the composition and contents of Royal Jelly (RJ) vary. The discrepancies found are most likely attributable to the variable number of samples collected from various locations and at ...
Rahul Dubey, Sathiyanarayanan Lohidasan, Laxmi Rao, Suhas Mohite   +3 more
openaire   +1 more source

10-HDA attenuates inflammatory responses in LPS-activated RAW264.7 cells in vitro via the NUR77/NF-κB pathways and improving mitochondrial functions

Frontiers in Pharmacology
BackgroundInflammation is implicated in the pathogenesis of various diseases, including cancer, diabetes, and diseases caused by bacterial infections. Macrophages, as key regulators of inflammatory responses, can polarize into distinct phenotypes such as
Kangwei Zhang, Kangwei Zhang, Zhen Zhou, Zhen Zhou, Haoxiang Ou, Haoxiang Ou, Xiaoli Fu, Xiaoli Fu, Jiaqi Xiao, Jiaqi Xiao, Xinyi Pan, Xinyi Pan, Long Wang, Bo Xu, Yanting Su, Mingjie Wei, Zhenwang Zhang, Liqiong Huang, Yongfen Bao, Yongfen Bao, Shigang Shan, Shigang Shan   +21 more
doaj   +1 more source

Quality Parameters for Commercial Royal Jelly

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2016
Royal jelly has become a high-value commercial product and the standardization of this product is required to guarantee its quality on the market. The objective of the research activity was to pursue the chemical composition of commercial samples of ...
Carmen Ioana Muresan, Liviu Alexandru Mărghitaș, Daniel Severus Dezmirean, Otilia Bobiș, Victorița Bonta, Iulia Zacharias, Rodica Mărgăoan, Claudia Pașca   +7 more
doaj   +1 more source

Characterization of the MYB Genes Reveals Insights Into Their Evolutionary Conservation, Structural Diversity, and Functional Roles in Magnaporthe oryzae

Frontiers in Microbiology, 2021
The myeloblastosis (MYB) transcription factor family is evolutionarily conserved among plants, animals, and fungi, and contributes to their growth and development.
Sehee Lee, Ronny Völz, Hyeunjeong Song, William Harris, Yong-Hwan Lee, Yong-Hwan Lee, Yong-Hwan Lee, Yong-Hwan Lee, Yong-Hwan Lee   +8 more
doaj   +1 more source

Determination of total protein, trans- 10-Hydroxy-2-Decenoic Acid (10-HDA) and major royal jelly proteins in royal jelly produced at different harvest times in queenless and queenright colonies

Harran Tarım ve Gıda Bilimleri Dergisi, 2022
Two of the most important ingredients to add functional properties to royal jelly are 10-HDA and major royal jelly proteins (MRJPs). The effect of royal jelly (RJ) production and the effect of royal jelly harvest time (24, 48 and 72 hours) on 10-HDA, the total protein content of RJ, and molecular weights of major proteins in RJ were investigated in ...
Aytül Uçak Koç, Mete Karacaoğlu, Zehra Burcu Bakır, Kadir Kızılkaya   +3 more
openaire   +2 more sources

Ten-year radiographic and functional outcomes in rheumatoid arthritis patients in remission compared to patients in low disease activity

Arthritis Research & Therapy, 2023
Background To compare the 10-year structural and functional prognosis between patients in sustained remission versus patients in sustained low disease activity (LDA) in early rheumatoid arthritis (RA).
Adeline Ruyssen-Witrand, Gregory Guernec, Julia Dupont, Diane Lapuyade, Frédéric Lioté, Olivier Vittecoq, Yannick Degboé, Arnaud Constantin   +7 more
doaj   +1 more source

Design of Experiments-Assisted Development of Clotrimazole-Loaded Ionic Polymeric Micelles Based on Hyaluronic Acid

Nanomaterials, 2020
Polymeric micelles based on amphiphilic polysaccharides have some advantages as a carrier of poorly soluble lipophilic drugs thanks to their characteristic "core–shell" structure.
Laura Catenacci, Giorgio Marrubini, Milena Sorrenti, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, Valentina Fagnani, Caterina Valentino, Maria Cristina Bonferoni   +8 more
doaj   +1 more source