Results 151 to 160 of about 2,113 (192)

Study of Royal Jelly effect on serum levels of IL-4, TNF- α, TGF-B, and IFN-γ in multiple sclerosis patients in comparison with Omega-3; A double-blind, randomized, clinical trial. [PDF]

Avicenna J Phytomed
Majdinasab N, Aghaei A, Siahpoosh A, Motamedi R, Hosseini SA, Malayeri A.   +5 more
europepmc   +1 more source

Down‐regulation of aquaporin 9 gene transcription by 10‐hydroxy‐2‐decenoic acid: A major fatty acid in royal jelly

Down‐regulation of aquaporin 9 gene transcription by 10‐hydroxy‐2‐decenoic acid: A major fatty acid in royal jelly
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10-Hydroxy-2-decenoic acid from Royal jelly: A potential medicine for RA

Journal of Ethnopharmacology, 2010
Rheumatoid arthritis synovial fibroblasts (RASFs) are known to produce matrix metalloproteinases (MMPs) and cause joint destruction. The purpose of this study is to develop a potential medicine for rheumatoid arthritis (RA).To this end, first, the MMPs inhibition factor was purified from an alkali-solubilized fraction of RJ (Apis mellifera) by C18 ...
Xin-Yu, Yang, De-sheng, Yang, , Wei-Zhang, Jian-Min, Wang, Chun-Yang, Li, , Hui-Ye, Kang-Fu, Lei, Xiu-Fang, Chen, Nian-Han, Shen, Li-Qin, Jin, Jian-Guang, Wang   +10 more
openaire   +4 more sources

Biosynthesis of 10-Hydroxy-2-decenoic Acid through a One-Step Whole-Cell Catalysis

Journal of Agricultural and Food Chemistry
10-Hydroxy-2-decenoic acid (10-HDA) is an important component of royal jelly, known for its antimicrobial, anti-inflammatory, blood pressure-lowering, and antiradiation effects. Currently, 10-HDA biosynthesis is limited by the substrate selectivity of acyl-coenzyme A dehydrogenase, which restricts the technique to a two-step process.
Ke Fang, Ziting Xu, Lu Yang, Quan Cui, Bowen Du, Huijing Liu, Ruiming Wang, Piwu Li, Jing Su, Junqing Wang   +9 more
openaire   +4 more sources

The neuroprotective effect of 10-hydroxy-2-decenoic acid in traumatic brain injury by inhibiting copper-mediated neuronal pyroptosis

Phytomedicine
10‑hydroxy-2-decenoic acid (10-HDA), the major fatty acid in royal jelly, exhibits antibacterial, anti-inflammatory, and antioxidant properties, suggesting its potential therapeutic benefits for traumatic brain injury (TBI). TBI induces significant neurological deficits through cell death, including pyroptosis. Although the role of copper in cell death
Xinqi Huang, Yumei An, Jingxuan Liu, Mingyuan Xu, Xianzhe Li, Xueshi Chen, Haiyan Shan, Mingyang Zhang   +7 more
openaire   +4 more sources

Production of 10‐Hydroxy‐2‐decenoic Acid from Decanoic Acid via Whole‐Cell Catalysis in Engineered Escherichia coli

ChemSusChem, 2021
Abstract10‐Hydroxy‐2‐decenoic acid (10‐HDA) is a terminal hydroxylated medium‐chain α,β‐unsaturated carboxylic acid that performs various unique physiological activities and has a wide market value. Therefore, development of an environmentally friendly, safe, and high‐efficiency route to synthesize 10‐HDA is required.
Yan Li, Junqing Wang, Fen Wang, Li Wang, Leilei Wang, Ziqi Xu, Haibo Yuan, Xiaohui Yang, Piwu Li, Jing Su, Ruiming Wang   +10 more
openaire   +2 more sources

Absence of 10-Hydroxy-2-Decenoic Acid (10-HDA) in Bee-Collected Pollen

1986
Much attention has been paid to the survival of bee-collected pollen in pellets as well as those sticking to body hairs. This interest stems from plant breeders concern to prevent contamination when using bees for pollination purposes in isolation cages on the one hand and, on the other hand, one would like to use bee-collected pollen to improve seed ...
Verhoef, H.C.M., Hoekstra, F.A.
openaire   +2 more sources

Comparative proteomic analysis provides insight into 10-hydroxy-2-decenoic acid biosynthesis in honey bee workers

Amino Acids, 2017
10-Hydroxy-2-decenoic acid (10-HDA) is the major compound produced from the mandibular glands (MGs) of honey bee workers. However, little information is available on the molecular mechanisms of 10-HDA biosynthesis. In our study, based on investigating the 10-HDA secretion pattern and the morphological characteristics of MGs from honey bee workers of ...
Xiao-Hui, Yang, Shi-Fa, Yang, Rui-Ming, Wang   +2 more
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Biosynthesis of 10-Hydroxy-2-Decenoic Acid in Escherichia coli

Metabolic Engineering
10-hydroxy-2-decenoic acid (10-HDA), a unique unsaturated fatty acid present in royal jelly, has attracted considerable interest due to its potential medical applications. However, its low concentration in royal jelly and complex conformational structure present challenges for large-scale production. In this study, we designed and constructed a de novo
Dan, He, Yan, Chen, Junfeng, Shen, Han, Yu, Jay D, Keasling, Xiaozhou, Luo   +5 more
openaire   +2 more sources