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10‐Hydroxy‐2‐decenoic acid prevents ultraviolet A‐induced damage and matrix metalloproteinases expression in human dermal fibroblasts

Journal of the European Academy of Dermatology and Venereology, 2012
AbstractBackground  10‐Hydroxy‐2‐decenoic acid (10‐HDA) is a major fatty acid component of royal jelly, which has been reported to have a variety of beneficial pharmacological characteristics. However, the effects of 10‐HDA on skin photoageing and its potential mechanism of action are unclear.Objective  We investigated the protective effects of 10‐HDA ...
Jinfen, Zheng   +6 more
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Determination of 10-hydroxy-2-decenoic acid in products with royal jelly

2015
Matična mliječ je prirodni eliksir koji čuva zdravlje i vitalnost čovjeka. Od njezinih mnogobrojnih sastojaka izdvaja se 10-hidroksi-2-decenska kiselina (10-HDA), u prirodi prisutna samo u matičnoj mliječi. Ona ima važne biološke učinke od kojih se izdvajaju antibakterijsko, protuupalno i imunmodulatorsko djelovanje.
Lalić, Zdenka   +2 more
openaire  

HPLC determination of pkavalue of 10-hydroxy-2-decenoic acid

Journal of Liquid Chromatography & Related Technologies, 2018
The utilization of HPLC methods is very useful for the determination of some physicochemical characteristics of compounds.
T. Angelov, I. Hristov
openaire   +1 more source

Effects of 10-Hydroxy-2-decenoic acid on the development of honey bee (Apis mellifera) larvae

Journal of Apicultural Research, 2014
SummaryHoney bee queens and workers, both of which are female, develop from the same type of genome, but they have substantial morphological and physiological differences. Epigenetic modifications have been suggested to be involved in caste differentiation that is induced by royal jelly. 10-hydroxy-2(E)-decenoic acid (10-HDA), which can inhibit histone
Wen Xiang Wang   +4 more
openaire   +1 more source

The neuroprotective effect of 10-hydroxy-2-decenoic acid in traumatic brain injury by inhibiting copper-mediated neuronal pyroptosis

Phytomedicine
10‑hydroxy-2-decenoic acid (10-HDA), the major fatty acid in royal jelly, exhibits antibacterial, anti-inflammatory, and antioxidant properties, suggesting its potential therapeutic benefits for traumatic brain injury (TBI). TBI induces significant neurological deficits through cell death, including pyroptosis. Although the role of copper in cell death
Mingyang Zhang, Haiyan Shan, Yumei An
exaly   +3 more sources

Effects of 10-hydroxy-2-decenoic acid on phagocytosis and cytokines production of peritoneal macrophages in vitro.

Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999
To study the effect of 10-hydroxy-2-decenoic acid (HDA) on the macrophages activity of rats in vitro.To measure the effects of HDA on phagocytosis, the production of antitumor cytokines tumor necrosis factor (TNF) and interleukin-1 (IL-1) in vitro.HDA 50, 100 mg.L-1 promoted phagocytic activity from 0.353 +/- 0.017 to 0.39 +/- 0.04 and 0.382 +/- 0.017 ...
G Y, Wang, Z B, Lin
openaire   +1 more source

Biological Origin and Configuration of 10-Hydroxy-Δ2-decenoic Acid

Nature, 1959
WE have recently established1 that 10-hydroxy-Δ2-decenoic acid, which constitutes about 15 per cent of royal jelly, is not present in the free state in pollens of representative species, nectar or honey. We suggested that it might therefore be present in combined form or be a specific bee product.
S. A. BARKER   +3 more
openaire   +2 more sources

Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy

European Journal of Nutrition, 2019
Neuroinflammation is thought to be associated with the pathogenesis of a series of neurodegenerative diseases. We have previously reported that royal jelly (RJ) has an anti-inflammatory effect on microglial BV-2 cells. However, components contributing to the effect of RJ were largely unexplored.
Mengmeng You   +3 more
openaire   +2 more sources

10-Hydroxy-2-decenoic acid-derived aldehydes attenuate anaphylactic hypothermia in vivo

PharmaNutrition, 2022
Akira Sato   +2 more
openaire   +1 more source

10-Hydroxy-2-decenoic acid attenuates nonalcoholic fatty liver disease by activating AMPK-α signaling pathway

Biochemical Pharmacology
Nonalcoholic fatty liver disease (NAFLD) originates from metabolic dysfunctions, is one of the most commonly encountered liver disorders worldwide, characterized by ectopic lipid deposition within hepatocytes, accompanied by hepatocellular injury and necroinflammation. Currently, NAFLD has very few treatment options.
Minyi Tang   +8 more
openaire   +2 more sources

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