In this study, we optimized the melt polycondensation of 10-hydroxy-2-decenoic acid (10-HDA) to produce poly(10-hydroxy-2-decenoate) (PHDA) and used it to form crosslinked polyester films of PHDA via thermal- or photocuring.
Ziqi Xu +6 more
doaj +2 more sources
Behind the Therapeutic Effects of Royal Jelly: Recent Advances in the Specific Properties of 10-Hydroxydecanoic Acid [PDF]
Since ancient times, Royal Jelly (RJ) has been known for its remarkable properties in traditional medicine, and it is still widely recommended for mental and physical well-being.
Carla Gasbarri, Guido Angelini
doaj +2 more sources
10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells [PDF]
Vascular endothelial growth factor (VEGF) is reported to be a potent pro-angiogenic factor that plays a pivotal role in both physiological and pathological angiogenesis.
Autiero +28 more
core +5 more sources
Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health [PDF]
A differential diet with royal jelly (RJ) during early larval development in honeybees shapes the phenotype, which is probably mediated by epigenetic regulation of gene expression.
Fernanda Aparecida dos Santos France +8 more
doaj +2 more sources
Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [PDF]
Background Royal jelly (RJ) has traditionally been used to maintain health, and its fatty acids (10-hydroxy decanoic acid and 10-hydroxy-2-decenoic acid) are reported to have immunomodulatory effects.
Shuhei Nonobe +5 more
doaj +2 more sources
Dissecting the Molecular Mechanism of 10-HDA Biosynthesis: Role of Acyl-CoA Delta(11) Desaturase and Transcriptional Regulators in Honeybee Mandibular Glands [PDF]
10-Hydroxy-2-decenoic acid (10-HDA), a major fatty acid (FA) component of royal jelly, is synthesized in the mandibular glands (MGs) of worker honeybees.
Yunchang Li +3 more
doaj +2 more sources
Enhancing 10-HDA production of Escherichia coli by heterologous expression of MexHID transporter proteins [PDF]
10-Hydroxy-2-decenoic acid (10-HDA) is a medium-chain α,β-unsaturated carboxylic acid that exists in royal jelly with terminal hydroxylation. It has a broad market value because of its antibacterial, anti-inflammatory, anti-tumor, anti-radiation, and ...
Ziting Xu +11 more
doaj +2 more sources
Oleic Acid Promotes the Biosynthesis of 10-Hydroxy-2-decenoic Acid via Species-Selective Remodeling of TAGs in Apis mellifera ligustica. [PDF]
This study aimed to assess the impact of oleic acid (OA) supplementation on the biosynthesis of 10-hydroxy-2-decenoic acid (10-HDA) in Apis mellifera ligustica. In experiment 1, varying concentrations of OA (2%, 4%, 6% and 8%) were added to an artificial diet for newly emerged bees reared in cages.
Hu X +6 more
europepmc +3 more sources
10-Hydroxy-2-Decenoic Acid Prevents Ultraviolet A-Induced Expression of Lamin AÄ150 in Human Dermal Fibroblasts. [PDF]
10-Hydroxy-2-decenoic acid (10-HDA) as the main component of royal jelly has pharmacological characteristics. But the influence of 10-HDA on skin photoaging and photo damage is poorly understood. In the present study, we used 10-HAD immediately after UVA exposure and tested the effects on the attenuation of LMNAÄ150 expression in cultured human dermal ...
Mirbaha S, Bagheri M, Mahmoudi-Nejad S.
europepmc +3 more sources
Metabolic Reprogramming for Body Adaptation and Inflammatory Control in Eccentric Damaging Exercise: Comprehensive Molecular Insights From Repeated Downhill Running. [PDF]
MedComm, Volume 6, Issue 11, November 2025.
Malvandi AM +10 more
europepmc +2 more sources

