The purposes of this study were to explore the potential possibility of 10-hydroxy-trans-2-decenoic acid (10-HDA) use in feeding broiler chickens. A total of 216 healthy 1-day-old chicks were divided into 2 treatments at random (diets supplemented with 0
Yuxin Zhang +6 more
doaj +2 more sources
Efficient Biosynthesis of 10-Hydroxy-2-decenoic Acid Using a NAD(P)H Regeneration P450 System and Whole-Cell Catalytic Biosynthesis. [PDF]
10-Hydroxy-2-decenoic acid (10-HDA) is an α,β-unsaturated medium-chain carboxylic acid containing a terminal hydroxyl group. It has various unique properties and great economic value. We improved the two-step biosynthesis method of 10-HDA. The conversion
Wang L +9 more
europepmc +2 more sources
Behind the Therapeutic Effects of Royal Jelly: Recent Advances in the Specific Properties of 10-Hydroxydecanoic Acid [PDF]
Since ancient times, Royal Jelly (RJ) has been known for its remarkable properties in traditional medicine, and it is still widely recommended for mental and physical well-being.
Carla Gasbarri, Guido Angelini
doaj +2 more sources
Integration of Metabolomic and Transcriptomic Provides Insights into Anti-Inflammatory Response to trans-10-Hydroxy-2-decenoic Acid on LPS-Stimulated RAW 264.7 Cells. [PDF]
Trans-10-hydroxy-2-decenoic acid (10-HDA) is a unique fatty acid found in royal jelly that possesses potential health benefits such as anti-inflammatory.
Huang M +5 more
europepmc +2 more sources
Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [PDF]
Background Royal jelly (RJ) has traditionally been used to maintain health, and its fatty acids (10-hydroxy decanoic acid and 10-hydroxy-2-decenoic acid) are reported to have immunomodulatory effects.
Shuhei Nonobe +5 more
doaj +2 more sources
Anti-Tumor Effects of Queen Bee Acid (10-Hydroxy-2-Decenoic Acid) Alone and in Combination with Cyclophosphamide and Its Cellular Mechanisms against Ehrlich Solid Tumor in Mice. [PDF]
Queen bee acid or 10-hydroxy-2-decenoic acid (10-HDA) is one of the main and unique lipid components (fatty acids) in royal jelly. Previous studies have demonstrated that 10-HDA has various pharmacological and biological activities.
Albalawi AE +5 more
europepmc +2 more sources
10-Hydroxy-2-Decenoic Acid Prevents Ultraviolet A-Induced Expression of Lamin AÄ150 in Human Dermal Fibroblasts. [PDF]
10-Hydroxy-2-decenoic acid (10-HDA) as the main component of royal jelly has pharmacological characteristics. But the influence of 10-HDA on skin photoaging and photo damage is poorly understood. In the present study, we used 10-HAD immediately after UVA exposure and tested the effects on the attenuation of LMNAÄ150 expression in cultured human dermal ...
Mirbaha S, Bagheri M, Mahmoudi-Nejad S.
europepmc +3 more sources
Chemical Markers and Bioactivity of Algerian Royal Jelly: Influence of Bee Subspecies, Geography, and Lyophilization. [PDF]
Algerian royal jelly from native honey bees shows chemical diversity influenced by geography and subspecies. Lyophilization preserves key compounds, including 10‐HDA and phenolics. Biological assays reveal modest antioxidant activity and selective cytotoxicity against Reh leukemia cells, while anti‐inflammatory effects are limited.
Ayad AS +7 more
europepmc +2 more sources
Royal jelly is a yellowish-white substance with a gel texture that is secreted from the hypopharyngeal and mandibular glands of young worker bees. It consists mainly of water (50–56%), proteins (18%), carbohydrates (15%), lipids (3–6%), minerals (1.5 ...
Eleni Spanidi +5 more
doaj +1 more source
DETERMINATION OF 10 - HYDROXY - 2 - DECENOIC ACID IN ROYAL JELLY BY CAPILLARY ELECTROPHORESIS [PDF]
ABSTRACT Two commercial samples of Royal Jelly sold in Chile, consisting of two imported sample and another sample of known origin obtained freshly harvested from beekeepers were analyzed. The application of capillary electrophoresis (CE) for the separation and determination of the active compound, 10 hydroxy –2 – decenoic acid, in Royal Jelly (RJ) in ...
MUÑOZ, ORLANDO +4 more
openaire +2 more sources

