Results 21 to 30 of about 717,782 (176)

Hydroxy decenoic acid down regulates gtfB and gtfC expression and prevents Streptococcus mutans adherence to the cell surfaces [PDF]

Annals of Clinical Microbiology and Antimicrobials, 2012
Background 10-Hydroxy-2-decenoic acid, an unsaturated fatty acid is the most active and unique component to the royal jelly that has antimicrobial properties.
Yousefi Behnam, Ghaderi Shahrooz, Rezapoor-Lactooyi Alireza, Amiri Niusha, Verdi Javad, Shoae-Hassani Alireza   +5 more
doaj   +2 more sources

Efficient Biosynthesis of 10-Hydroxy-2-decenoic Acid Using a NAD(P)H Regeneration P450 System and Whole-Cell Catalytic Biosynthesis. [PDF]

ACS Omega, 2022
10-Hydroxy-2-decenoic acid (10-HDA) is an α,β-unsaturated medium-chain carboxylic acid containing a terminal hydroxyl group. It has various unique properties and great economic value. We improved the two-step biosynthesis method of 10-HDA. The conversion
Wang L, Wang L, Wang R, Wang Z, Wang J, Yuan H, Su J, Li Y, Yang S, Han T.   +9 more
europepmc   +2 more sources

Behind the Therapeutic Effects of Royal Jelly: Recent Advances in the Specific Properties of 10-Hydroxydecanoic Acid [PDF]

Molecules
Since ancient times, Royal Jelly (RJ) has been known for its remarkable properties in traditional medicine, and it is still widely recommended for mental and physical well-being.
Carla Gasbarri, Guido Angelini
doaj   +2 more sources

Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [PDF]

BMC Complementary Medicine and Therapies
Background Royal jelly (RJ) has traditionally been used to maintain health, and its fatty acids (10-hydroxy decanoic acid and 10-hydroxy-2-decenoic acid) are reported to have immunomodulatory effects.
Shuhei Nonobe, Hideto Okamoto, Takashi Ito, Hayate Itatani, Ayanori Yamaki, Nobuaki Okumura   +5 more
doaj   +2 more sources

Integration of Metabolomic and Transcriptomic Provides Insights into Anti-Inflammatory Response to trans-10-Hydroxy-2-decenoic Acid on LPS-Stimulated RAW 264.7 Cells. [PDF]

Int J Mol Sci, 2023
Trans-10-hydroxy-2-decenoic acid (10-HDA) is a unique fatty acid found in royal jelly that possesses potential health benefits such as anti-inflammatory.
Huang M, Dong J, Tan X, Yang S, Xiao M, Wang D.   +5 more
europepmc   +2 more sources

Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health [PDF]

Epigenetics
A differential diet with royal jelly (RJ) during early larval development in honeybees shapes the phenotype, which is probably mediated by epigenetic regulation of gene expression.
Fernanda Aparecida dos Santos France, Debora Kazumi Maeda, Ana Beatriz Rodrigues, Mai Ono, Franciele Lopes Nogueira Marchetti, Marcos Martins Marchetti, Allana Cristina Faustino Martins, Roberto da Silva Gomes, Cláudia Aparecida Rainho   +8 more
doaj   +2 more sources

Anti-Tumor Effects of Queen Bee Acid (10-Hydroxy-2-Decenoic Acid) Alone and in Combination with Cyclophosphamide and Its Cellular Mechanisms against Ehrlich Solid Tumor in Mice. [PDF]

Molecules, 2021
Queen bee acid or 10-hydroxy-2-decenoic acid (10-HDA) is one of the main and unique lipid components (fatty acids) in royal jelly. Previous studies have demonstrated that 10-HDA has various pharmacological and biological activities.
Albalawi AE, Althobaiti NA, Alrdahe SS, Alhasani RH, Alaryani FS, BinMowyna MN.   +5 more
europepmc   +2 more sources

Chemical Markers and Bioactivity of Algerian Royal Jelly: Influence of Bee Subspecies, Geography, and Lyophilization. [PDF]

Chem Biodivers
Algerian royal jelly from native honey bees shows chemical diversity influenced by geography and subspecies. Lyophilization preserves key compounds, including 10‐HDA and phenolics. Biological assays reveal modest antioxidant activity and selective cytotoxicity against Reh leukemia cells, while anti‐inflammatory effects are limited.
Ayad AS, Hébert MPA, Doiron JA, Loucif-Ayad W, Daas T, Smagghe G, Touaibia M, Surette ME.   +7 more
europepmc   +2 more sources

Multi-Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation. [PDF]

Food Sci Nutr
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Elrherabi A, Khibech O, Bouhrim M, Laftouhi A, Shahat AA, Alanzi AR, Herqash RN, Basilua JM, Bnouham M.   +8 more
europepmc   +2 more sources

Royal Jelly Components Encapsulation in a Controlled Release System—Skin Functionality, and Biochemical Activity for Skin Applications

Pharmaceuticals, 2022
Royal jelly is a yellowish-white substance with a gel texture that is secreted from the hypopharyngeal and mandibular glands of young worker bees. It consists mainly of water (50–56%), proteins (18%), carbohydrates (15%), lipids (3–6%), minerals (1.5 ...
Eleni Spanidi, Sophia Athanasopoulou, Angeliki Liakopoulou, Angeliki Chaidou, Sophia Hatziantoniou, Konstantinos Gardikis   +5 more
doaj   +1 more source