Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [PDF]
BMC Complementary Medicine and TherapiesBackground Royal jelly (RJ) has traditionally been used to maintain health, and its fatty acids (10-hydroxy decanoic acid and 10-hydroxy-2-decenoic acid) are reported to have immunomodulatory effects.
Shuhei Nonobe +5 more
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Oleic Acid Promotes the Biosynthesis of 10-Hydroxy-2-decenoic Acid via Species-Selective Remodeling of TAGs in Apis mellifera ligustica. [PDF]
Int J Mol Sci, 2023 This study aimed to assess the impact of oleic acid (OA) supplementation on the biosynthesis of 10-hydroxy-2-decenoic acid (10-HDA) in Apis mellifera ligustica. In experiment 1, varying concentrations of OA (2%, 4%, 6% and 8%) were added to an artificial diet for newly emerged bees reared in cages.
Hu X +6 more
europepmc +3 more sources
Effects of 10-Hydroxy-2-decenoic Acid and 10-Hydroxydecanoic Acid in Royal Jelly on Bone Metabolism in Ovariectomized Rats: A Pilot Study. [PDF]
J Clin Med, 2023 Although previous studies have demonstrated that royal jelly (RJ) may have estrogenic properties and prevent postmenopausal bone loss, the underlying mechanisms are not fully understood. This animal study aimed to investigate the effects of specific fatty acids of RJ, 10-hydroxy-2-decenoic acid (10H2DA) and 10-hydroxydecanoic acid (10HDAA), in ...
Hanai R +7 more
europepmc +3 more sources
10-Hydroxy-2-Decenoic Acid Prevents Ultraviolet A-Induced Expression of Lamin AÄ150 in Human Dermal Fibroblasts. [PDF]
Maedica (Bucur), 2019 10-Hydroxy-2-decenoic acid (10-HDA) as the main component of royal jelly has pharmacological characteristics. But the influence of 10-HDA on skin photoaging and photo damage is poorly understood. In the present study, we used 10-HAD immediately after UVA exposure and tested the effects on the attenuation of LMNAÄ150 expression in cultured human dermal ...
Mirbaha S, Bagheri M, Mahmoudi-Nejad S.
europepmc +3 more sources
Down-regulation of aquaporin 9 gene transcription by 10-hydroxy-2-decenoic acid: A major fatty acid in royal jelly. [PDF]
Food Sci Nutr, 2019 Abstract10‐Hydroxy‐trans‐2‐decenoic acid (10H2DA) is a unique lipid component of royal jelly produced by worker honeybees that exerts insulin‐like effects. We herein investigated the effects of 10H2DA on the gene expression of aquaporin 9 (AQP9), which functions as a glycerol transporter in the liver, to clarify whether 10H2DA modulates energy ...
Usui S +6 more
europepmc +4 more sources
Pharmaceuticals, 2022 Royal jelly is a yellowish-white substance with a gel texture that is secreted from the hypopharyngeal and mandibular glands of young worker bees. It consists mainly of water (50–56%), proteins (18%), carbohydrates (15%), lipids (3–6%), minerals (1.5 ...
Eleni Spanidi +5 more
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DETERMINATION OF 10 - HYDROXY - 2 - DECENOIC ACID IN ROYAL JELLY BY CAPILLARY ELECTROPHORESIS [PDF]
Journal of the Chilean Chemical Society, 2011 ABSTRACT Two commercial samples of Royal Jelly sold in Chile, consisting of two imported sample and another sample of known origin obtained freshly harvested from beekeepers were analyzed. The application of capillary electrophoresis (CE) for the separation and determination of the active compound, 10 hydroxy –2 – decenoic acid, in Royal Jelly (RJ) in ...
MUÑOZ, ORLANDO +4 more
openaire +2 more sources
Natural Product Communications, 2020 Royal jelly (RJ) is a bee product that has high nutritional value and is beneficial for the human health, earning importance as a functional food. Thus, the characterization of its main biological properties is with high importance.
Soukaïna El-Guendouz +6 more
doaj +1 more source
Synthesis of 10-Hydroxy-2-decenoic Acid (Royal Jelly Acid) from the Butadiene Telomer [PDF]
Bulletin of the Chemical Society of Japan, 1977 Abstract Ethyl 2-acetyl-4,9-decadienoate obtained by palladium catalyzed reaction of butadiene and ethyl acetoacetate was converted to 4,9-decadienoate. Hydroboration of the terminal olefin gave 10-hydroxy-4-decenoate. After hydrogenation and protection of the hydroxyl group, the double bond was created at the conjugated position by ...
Jiro Tsuji +4 more
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Recent Advances in Determination Methods of Fatty Acid Markers in Royal Jelly
Shipin gongye ke-ji, 2023 Royal jelly is a yellowish, creamy and acidic substance secreted by mandibular and hypopharyngeal glands of young worker bees. Fatty acids including (E)-10-hydroxy-2-decenoic acid, 10-hydroxydecanoic acid, 3,10-dihydroxydecanoic acid, 8-hydroxyoctanoic ...
Xinyu YU +4 more
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