In vitro anti-Toxoplasma effects and apoptotic induction of queen bee acid (10-hydroxy-2-decenoic acid) alone and in combination with atovaquone [PDF]
Toxoplasmosis, which is created by the Toxoplasma gondii parasite is a parasitic, infectious disease. 10-hydroxy-2-decenoic acid (10-H2DA, queen bee acid (QBA), is one of the most prevalent fatty acid (>40%) presents in royal jelly.
Panteha Asgari, Siavash Pourhossein
doaj +6 more sources
Total Protein and 10-Hydroxy-2-Decenoic Acid Content, In Vitro Bioaccessibility, Antibacterial, and Antidiabetic Properties of Royal Jelly Collected at Different Harvesting Times. [PDF]
In this study, the total protein content and 10‐hydroxy‐2‐decenoic acid content were determined in royal jelly collected at the 72 and 144 h. In vitro bioaccessibility, antibacterial, and antidiabetic properties of royal jelly collected at the 72 and 144 h were also determined. ABSTRACT Royal jelly has received interest as a functional food.
Welelaw E +9 more
europepmc +3 more sources
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj +4 more sources
Effects of 10-Hydroxy-2-decenoic Acid and 10-Hydroxydecanoic Acid in Royal Jelly on Bone Metabolism in Ovariectomized Rats: A Pilot Study. [PDF]
Although previous studies have demonstrated that royal jelly (RJ) may have estrogenic properties and prevent postmenopausal bone loss, the underlying mechanisms are not fully understood. This animal study aimed to investigate the effects of specific fatty acids of RJ, 10-hydroxy-2-decenoic acid (10H2DA) and 10-hydroxydecanoic acid (10HDAA), in ...
Hanai R +7 more
europepmc +4 more sources
Oleic Acid Promotes the Biosynthesis of 10-Hydroxy-2-decenoic Acid via Species-Selective Remodeling of TAGs in Apis mellifera ligustica. [PDF]
This study aimed to assess the impact of oleic acid (OA) supplementation on the biosynthesis of 10-hydroxy-2-decenoic acid (10-HDA) in Apis mellifera ligustica. In experiment 1, varying concentrations of OA (2%, 4%, 6% and 8%) were added to an artificial diet for newly emerged bees reared in cages.
Hu X +6 more
europepmc +4 more sources
Down-regulation of aquaporin 9 gene transcription by 10-hydroxy-2-decenoic acid: A major fatty acid in royal jelly. [PDF]
Abstract10‐Hydroxy‐trans‐2‐decenoic acid (10H2DA) is a unique lipid component of royal jelly produced by worker honeybees that exerts insulin‐like effects. We herein investigated the effects of 10H2DA on the gene expression of aquaporin 9 (AQP9), which functions as a glycerol transporter in the liver, to clarify whether 10H2DA modulates energy ...
Usui S +6 more
europepmc +5 more sources
10-Hydroxy-2-decenoic Acid Suppresses Colorectal Cancer Progression by Inhibiting Wnt/β-Catenin Signaling and Promoting Apoptosis [PDF]
Colorectal cancer (CRC) remains a leading cause of cancer-related death worldwide, and advanced disease continues to show poor prognosis due to therapeutic limitations and drug resistance.
Yan Lin +9 more
doaj +2 more sources
Honey bees of Ethiopia: Their lineages and subspecies based on morphometrics, mitochondrial DNA, and mandibular gland pheromone analyses. [PDF]
Apiculture is a vital economic sector in Ethiopia, providing income and employment for over two million people. However, the classification of the honey bee subspecies in Ethiopia remains debatable.
Walellign Wotro Wanore +8 more
doaj +2 more sources
Biosynthesis of 10-Hydroxy-2-decenoic Acid through a One-Step Whole-Cell Catalysis
10-Hydroxy-2-decenoic acid (10-HDA) is an important component of royal jelly, known for its antimicrobial, anti-inflammatory, blood pressure-lowering, and antiradiation effects. Currently, 10-HDA biosynthesis is limited by the substrate selectivity of acyl-coenzyme A dehydrogenase, which restricts the technique to a two-step process.
Ke Fang +9 more
openaire +3 more sources
Hydroxy decenoic acid down regulates
Background 10-Hydroxy-2-decenoic acid, an unsaturated fatty acid is the most active and unique component to the royal jelly that has antimicrobial properties.
Yousefi Behnam +5 more
doaj +2 more sources

