In vitro anti-Toxoplasma effects and apoptotic induction of queen bee acid (10-hydroxy-2-decenoic acid) alone and in combination with atovaquone [PDF]
Toxoplasmosis, which is created by the Toxoplasma gondii parasite is a parasitic, infectious disease. 10-hydroxy-2-decenoic acid (10-H2DA, queen bee acid (QBA), is one of the most prevalent fatty acid (>40%) presents in royal jelly.
Panteha Asgari, Siavash Pourhossein
doaj +5 more sources
10-Hydroxy-2-decenoic Acid Suppresses Colorectal Cancer Progression by Inhibiting Wnt/β-Catenin Signaling and Promoting Apoptosis [PDF]
Colorectal cancer (CRC) remains a leading cause of cancer-related death worldwide, and advanced disease continues to show poor prognosis due to therapeutic limitations and drug resistance.
Yan Lin +9 more
doaj +2 more sources
Honey bees of Ethiopia: Their lineages and subspecies based on morphometrics, mitochondrial DNA, and mandibular gland pheromone analyses. [PDF]
Apiculture is a vital economic sector in Ethiopia, providing income and employment for over two million people. However, the classification of the honey bee subspecies in Ethiopia remains debatable.
Walellign Wotro Wanore +8 more
doaj +2 more sources
Multi-Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation. [PDF]
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200
Elrherabi A +8 more
europepmc +2 more sources
Metabolic Reprogramming for Body Adaptation and Inflammatory Control in Eccentric Damaging Exercise: Comprehensive Molecular Insights From Repeated Downhill Running. [PDF]
MedComm, Volume 6, Issue 11, November 2025.
Malvandi AM +10 more
europepmc +2 more sources
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj +3 more sources
<i>Cis</i>-2-decenoic acid modulates <i>Pseudomonas aeruginosa</i> virulence through a noncanonical transcriptional regulator. [PDF]
Abstract Diffusible signal factor (DSF)‐family quorum sensing (QS) signals are widely utilized by many pathogenic bacteria to modulate various biological functions and virulence. Previous studies showed that cis‐2‐decenoic acid (cis‐DA) is involved in the modulation of biofilm dispersion in Pseudomonas aeruginosa, but the regulatory mechanism is ...
Song S +15 more
europepmc +2 more sources
Effect of Protease-Treated Royal Jelly Extract on Facial Wrinkles: A Placebo-Controlled, Double-Blind, Parallel-Group Study. [PDF]
ABSTRACT Background No clinical trials have reported on the wrinkle‐improving effects of cosmetics which activate stem cells in vitro. Aims To evaluate the anti‐wrinkle effects of protease‐treated royal jelly (pRJ)‐containing cream application to the skin.
Ikegami S +11 more
europepmc +2 more sources
Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health [PDF]
A differential diet with royal jelly (RJ) during early larval development in honeybees shapes the phenotype, which is probably mediated by epigenetic regulation of gene expression.
Fernanda Aparecida dos Santos France +8 more
doaj +2 more sources
Behind the Therapeutic Effects of Royal Jelly: Recent Advances in the Specific Properties of 10-Hydroxydecanoic Acid [PDF]
Since ancient times, Royal Jelly (RJ) has been known for its remarkable properties in traditional medicine, and it is still widely recommended for mental and physical well-being.
Carla Gasbarri, Guido Angelini
doaj +2 more sources

