Results 11 to 20 of about 717,782 (176)

Effects of 10-Hydroxy-2-decenoic Acid and 10-Hydroxydecanoic Acid in Royal Jelly on Bone Metabolism in Ovariectomized Rats: A Pilot Study. [PDF]

J Clin Med, 2023
Although previous studies have demonstrated that royal jelly (RJ) may have estrogenic properties and prevent postmenopausal bone loss, the underlying mechanisms are not fully understood. This animal study aimed to investigate the effects of specific fatty acids of RJ, 10-hydroxy-2-decenoic acid (10H2DA) and 10-hydroxydecanoic acid (10HDAA), in ...
Hanai R, Matsushita H, Minami A, Abe Y, Tachibana R, Watanabe K, Takeuchi H, Wakatsuki A.   +7 more
europepmc   +5 more sources

Down-regulation of aquaporin 9 gene transcription by 10-hydroxy-2-decenoic acid: A major fatty acid in royal jelly. [PDF]

Food Sci Nutr, 2019
Abstract10‐Hydroxy‐trans‐2‐decenoic acid (10H2DA) is a unique lipid component of royal jelly produced by worker honeybees that exerts insulin‐like effects. We herein investigated the effects of 10H2DA on the gene expression of aquaporin 9 (AQP9), which functions as a glycerol transporter in the liver, to clarify whether 10H2DA modulates energy ...
Usui S, Soda M, Iguchi K, Abe N, Oyama M, Nakayama T, Kitaichi K.   +6 more
europepmc   +6 more sources

Dose-dependent immunomodulatory effects of 10-hydroxy-2-decenoic acid on human monocyte-derived dendritic cells [PDF]

Journal of Functional Foods, 2013
The effect of 10-hydroxy-2-decenoic acid (10-HDA), the unique component of royal jelly, on maturation and functions of human monocyte-derived dendritic cells (MoDCs) in culture was investigated. It has been shown that 10-HDA, at concentrations higher than 500 μM, induces apoptosis of MoDCs.
Ioanna Chinou, Miodrag Colic
exaly   +5 more sources

10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling [PDF]

Journal of Aging Research, 2015
Royal jelly (RJ) produced by honeybees has been reported to possess diverse health-beneficial properties and has been implicated to have a function in longevity across diverse species as well as honeybees.
Yoko Honda, Yoko Araki, Taketoshi Hata, Kenji Ichihara, Masafumi Ito, Masashi Tanaka, Shuji Honda   +6 more
doaj   +4 more sources

10-Hydroxy-2-Decenoic Acid in Royal Jelly Extract Induced Both Filaggrin and Amino Acid in a Cultured Human Three-Dimensional Epidermis Model [PDF]

Cosmetics, 2017
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj   +4 more sources

10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically [PDF]

Nature Communications
Osteoarthritis is a degenerative joint disease with joint pain as the main symptom, caused by fibrosis and loss of articular cartilage. Due to the complexity and heterogeneity of osteoarthritis, there is a lack of effective individualized disease ...
Nana Geng, Mengtian Fan, Biao Kuang, Fengmei Zhang, Menglin Xian, Lin Deng, Cheng Chen, Yiming Pan, Jianqiang Chen, Naibo Feng, Li Liang, Yuanlan Ye, Kaiwen Liu, Xiaoli Li, Yu Du, Fengjin Guo   +15 more
doaj   +2 more sources

10-Hydroxy-2-decenoic Acid Suppresses Colorectal Cancer Progression by Inhibiting Wnt/β-Catenin Signaling and Promoting Apoptosis [PDF]

Foods
Colorectal cancer (CRC) remains a leading cause of cancer-related death worldwide, and advanced disease continues to show poor prognosis due to therapeutic limitations and drug resistance.
Yan Lin, Rongjing Cai, Lei Huang, Tianxing Lin, Anqi Lin, Zhenyu Lin, Shoujie Jiang, Yuqi Zhu, Yuan Yuan, Songkun Su   +9 more
doaj   +2 more sources

10-Hydroxy-2-Decenoic Acid Prevents Ultraviolet A-Induced Expression of Lamin AÄ150 in Human Dermal Fibroblasts. [PDF]

Maedica (Bucur), 2019
10-Hydroxy-2-decenoic acid (10-HDA) as the main component of royal jelly has pharmacological characteristics. But the influence of 10-HDA on skin photoaging and photo damage is poorly understood. In the present study, we used 10-HAD immediately after UVA exposure and tested the effects on the attenuation of LMNAÄ150 expression in cultured human dermal ...
Mirbaha S, Bagheri M, Mahmoudi-Nejad S.
europepmc   +3 more sources

Honey bees of Ethiopia: Their lineages and subspecies based on morphometrics, mitochondrial DNA, and mandibular gland pheromone analyses. [PDF]

PLoS ONE
Apiculture is a vital economic sector in Ethiopia, providing income and employment for over two million people. However, the classification of the honey bee subspecies in Ethiopia remains debatable.
Walellign Wotro Wanore, Christian W W Pirk, Abdullahi A Yusuf, Steve B S Baleba, Mary Chege, Nelly N Ndungu, Abebe J Wubie, Workneh Ayalew, Beatrice T Nganso   +8 more
doaj   +2 more sources

10-Hydroxy-trans-2-decenoic Acid, a New Potential Feed Additive for Broiler Chickens to Improve Growth Performance [PDF]

Animals, 2022
The purposes of this study were to explore the potential possibility of 10-hydroxy-trans-2-decenoic acid (10-HDA) use in feeding broiler chickens. A total of 216 healthy 1-day-old chicks were divided into 2 treatments at random (diets supplemented with 0
Yuxin Zhang, Shixia Geng, Yuting Di, Yongbo Sun, Ying Liu, Juntao Li, Liying Zhang   +6 more
doaj   +2 more sources