Results 101 to 110 of about 618 (145)

Effect of renal replacement therapy on selected arachidonic acid derivatives concentration. [PDF]

open access: yesBMC Nephrol, 2020
Cecerska-Heryć E   +5 more
europepmc   +1 more source

Transformation of arachidonic acid into 12-hydroxy-5,8,10,14-eicosatetraenoic acid by mouse peritoneal macrophages

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
Mouse peritoneal macrophages were incubated at 37 degrees C for 30 min with arachidonic acid (all-cis-5,8,11,14-eicosatetraenoic acid). Oxygenation of arachidonic acid in mouse peritoneal macrophages occurs by two major pathways: fatty acid cyclooxygenase and lipoxygenase. The major metabolite of the latter is 12-hydroxy-5,8,10,14-eicosatetraenoic acid
Rigaud, M, Durand, J, Breton, J C
openaire   +2 more sources

In vivo transformation of arachidonic acid into 12-hydroxy-5,8,10,14-eicosatetraenoic acid by human nasal mucosa

Journal of Chromatography B: Biomedical Sciences and Applications, 1992
A method for the determination of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) by gas chromatography-mass spectrometry (GC-MS) in samples obtained from healthy subjects by nasal lavage is presented. HETEs were extracted from samples obtained by nasal lavage using C18 solid-phase cartridges. The purification of 12-HETE and 5-HETE was carried out
I, Ramis, J, Roselló-Catafau, E, Gelpí
openaire   +2 more sources

Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1994
The R and S enantiomers of 12-hydroxyeicosatetraenoic acid (12-HETE) exhibit different biological activities. Although they appear to be produced by different enzymatic pathways, cytochrome P-450 monooxygenase and lipoxygenase, respectively, they display similar metabolism in both corneal epithelium and neutrophils.
S, Yamamoto   +6 more
openaire   +2 more sources

Prostaglandin, thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
Production of several metabolites of arachidonic acid by purified rat serosal mast cells in response to stimulation with the ionophore A23187 was assessed by stable isotope dilution assay using gas chromatography-mass spectrometry. Compounds quantified were prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha, thromboxane B2, and 12-hydroxy-5,8,10,14 ...
L J, Roberts   +3 more
openaire   +2 more sources

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