Utility of 123I-MIBG Standardized Uptake Value in Patients with Refractory Pheochromocytoma and Paraganglioma [PDF]
Objective(s): Single-photon emission computed tomography (SPECT) using metaiodobenzylguanidine (MIBG) is an important diagnostic tool for the treatment of refractory pheochromocytoma and paraganglioma (PPGL).
Hiroshi Wakabayashi +10 more
doaj +1 more source
Reduced uptake of 123I-meta-iodobenzylguanidine (123I-MIBG) and orthostatic hypotension (OH) are independently associated with worse clinical outcomes of Parkinson’s disease (PD). However, their interactive influence on PD has not been studied.
Sang-Won Yoo +6 more
doaj +1 more source
ObjectiveThis study investigates the effects of manual and semi-automatic methods for assessing MIBG semi-quantitative indices in a clinical setting.Materials and methodsWe included 123I-MIBG scans obtained in 35 patients with idiopathic Parkinson’s ...
Cecilia Boccalini +14 more
doaj +1 more source
123I-MIBG Imaging: Patient Preparation and Technologist's Role [PDF]
The radiopharmaceutical (123)I-metaiodobenzylguanidine (MIBG) was approved by the Food and Drug Administration in March 2013 for the assessment of myocardial sympathetic innervation in the evaluation of patients with heart failure and an ejection fraction of no more than 35%.
S Seth, Van Vickle, Randall C, Thompson
openaire +2 more sources
Comparison of high-specific-activity ultratrace 123/131I-MIBG and carrier-added 123/131I-MIBG on efficacy, pharmacokinetics, and tissue distribution [PDF]
Metaiodobenzylguanidine (MIBG) is an enzymatically stable synthetic analog of norepinephrine that when radiolabled with diagnostic ((123)I) or therapeutic ((131)I) isotopes has been shown to concentrate highly in sympathetically innervated tissues such ...
Babich, John W +8 more
core +1 more source
Prediction of long-term cardiac events by 123I-MIBG imaging after acute myocardial infarction and reperfusion therapy [PDF]
Objective(s): In heart failure, the heart-to-mediastinum (H/M) ratio of the delayed image and washout rate (WR) are well-known as a powerful cardiac event predictors.
Manabu Nakamura +2 more
doaj +1 more source
Two Cases of Hereditary Paraganglioma-Pheochromocytoma Syndrome in Siblings, Caused by a Novel Succinate Dehydrogenase Complex Subunit D Variant. [PDF]
ABSTRACT Introduction Pheochromocytomas and paragangliomas are increasingly recognized as hereditary malignancies, with ~30%–40% of cases involving germline variants. We report a familial case of hereditary pheochromocytoma‐paraganglioma syndrome caused by a novel variant in the SDHD gene.
Nakamura R +9 more
europepmc +2 more sources
[(123)I]metaiodobenzylguanidine and [(111)In]octreotide uptake in begnign and malignant pheochromocytomas [PDF]
Selecting the appropriate approach for resection and follow-up of pheochromocytomas (PCCs) is highly dependent upon reliable localization and exclusion of multifocal, bilateral, or metastatic disease ...
Bonjer, H.J. (Jaap) +11 more
core +3 more sources
Renal sympathetic nerve activity after catheter-based renal denervation
Background Catheter-based renal sympathetic denervation (RDN) has been considered a potential treatment for therapy resistant hypertension (RHT). However, in a randomized placebo-controlled trial, RDN did not lead to a substantial blood pressure (BP ...
Linn C. Dobrowolski +8 more
doaj +1 more source
Aim. To investigate the relationship between radiological characteristics of epicardial adipose tissue (EAT) and myocardial sympathetic activity, as well as to study their association with late recurrence of atrial fibrillation (AF) after radiofrequency ...
Yu. V. Varlamova +7 more
doaj +1 more source

