Platelet derived growth factor receptor alpha is essential for establishing a microenvironment that supports definitive erythropoiesis [PDF]
, 2006 金沢大学大学院自然科学研究科大阪大学微生物病研究所 情報伝達分野The hematopoietic system undergoes a qualitative change during the embryogenesis of most vertebrates. It is designated as the shift of primitive to definitive hematopoiesis and suitable microenvironment must be established
Li Wen-Ling +5 more
core +2 more sources
Hypoxia and its Emerging Therapeutics in Neurodegenerative, Inflammatory and Renal Diseases [PDF]
, 2017 Hypoxia is a common underlying condition of many disease states. Hypoxia can occur with ischemia, a lack of blood flow to tissues, or independent of ischemia as in acute lung injury, anemia, and carbon monoxide poisoning.
Ardekani, Mohammad Sanaei +3 more
core +1 more source
Dynamics of erythropoietin receptor expression on erythropoietin- responsive murine cell lines [PDF]
, 1990 We examined erythropoietin receptor expression in two murine cell lines, B6SUtA and DA-1, that respond to erythropoietin in different ways. While B6SUtA cells undergo erythroid differentiation with limited proliferation after addition of erythropoietin ...
B Nakamoto +3 more
core +3 more sources
KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation [PDF]
, 1989 A human leukemic cell line KU 812 was recently established and described as a basophilic cell line. In the present study we show that KU 812 and two of its clones are at least bipotent: in addition to a minor component of basophils, the majority of KU ...
A Dubart +9 more
core +3 more sources
Studies on the specificities of In Vivo and In Vitro bioassays used in the potency determination of Therapeutic Erythropoietin [PDF]
, 2006 Erythropoietin (Epo), a kidney-produced cytokine, promotes the proliferation and differentiation of erythroid progenitors into mature red blood cells.The in vivo biological activity of Epo is dependent on it being adequately glycosylated.
Liefooghe, Emily Claire
core +1 more source
Isolation of the full-length murine erythropoietin receptor using a baculovirus expression system [PDF]
, 1996 The full-length murine erythropoietin receptor was expressed in Spodoptera frugiperda (Sf9) cells using a recombinant baculovirus vector. Erythropoietin receptor protein production was maximal 48 hours after infection, as determined by metabolic labeling
D Williams +5 more
core +1 more source
, 2022 Research and Practice in Thrombosis and Haemostasis, Volume 6, Issue S1, October 2022.
wiley +1 more source
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors
British Journal of Pharmacology, Volume 176, Issue S1, Page S247-S296, December 2019., 2019 The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander +20 more
wiley +1 more source
, 2021 Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
wiley +1 more source
Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V‐ATPase
Mediators of Inflammation, Volume 2019, Issue 1, 2019., 2019 A small group of only seven transcription factors known as STATs (signal transducer and activator of transcription) are considered to be canonical determinants of specific gene activation for a plethora of ligand/receptor systems. The activation of STATs involves a family of four tyrosine kinases called JAK kinases.
Howard M. Johnson +3 more
wiley +1 more source