Results 131 to 140 of about 6,987,667 (281)

Scientific drilling of the Boltysh impact crater, Ukraine [PDF]

open access: yes, 2009
Introduction: The Boltysh crater has been known for several decades and was first drilled in the 1960s as part of a study of economic oil shale deposits. Unfortunately, the cores were not curated and have been lost.
Gilmour, I.   +3 more
core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Desbordamientos culturales en torno al 15-M The 15-M movement in its cultural context

open access: yesRevista Teknokultura, 2013
Este artículo es una exploración del contexto cultural amplio del movimiento 15-M en el estado español. Comienza por proponer que el 15-M es un síntoma más de un generalizado desgaste de la hegemónica “Cultura de la transición”, que estableció una serie de acuerdos tácitos en torno a la necesidad de una sociedad vertical y de expertos basada en el ...
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

15-M. La reaparición de las luciérnagas

open access: yesNómadas. Revista Crítica de Ciencias Sociales y Jurídicas, 2012
La extraordinaria sorpresa provocada por el surgimiento del llamado movimiento 15-M tiende a dejar en segundo plano el agudo deterioro de las condiciones de vida de la poblacion espanola que lo ha generado. Asimismo, la enorme decepcion que el movimiento refleja hacia la llamada clase politica es una consecuencia del peculiar desarrollo historico ...
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

15-M, la gueule de bois

open access: yes, 2021
Le mouvement des Indignés, le 15-M, fut un mouvement d’une ampleur inédite, qui bouleversa des pans de la société espagnole. Il constitua, en Espagne et au-delà, un espoir de renouveau politique et social. C’était il y a dix ans déjà… Quelles traces en reste-t-il ? Le dossier de ce numéro tente de répondre à cette question.
openaire   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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