Results 151 to 160 of about 6,987,667 (281)
, 2018 En una democracia representativa la campaña electoral es la antesala del voto. El valor del sufragio depende del debate público que le precede. Una campaña abierta, plural y competitiva garantiza el voto libre y soberano. En las Elecciones Generales de 2004 y en las elecciones locales y autonómicas de 2011, los actos electorales fueron desplazados por ...
F. Sampedro Blanco, Víctor +1 more
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
15-M and the digital fifth-column
Revista Teknokultura, 2011 Social movements around May 15th have changed the political landscape. The use of some features such as networking, pacifism, transversality, represents a challenge for official politicians. Public space has been retaken and an impressive work has been generated without leaders.
Andoni Alonso, Iñaki Arzoz
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Madrid 15-M: lo poético político
, 2014 Guillermo G. Peydró, en su escrito “Madrid, 15-M: lo poético político” nos interpela a través de una pregunta coyuntural: ¿en qué medida puede lo poético ser político, evitar la esterilización inevitable del negocio del arte contemporáneo, provocar algún cambio real?
openaire +1 more source
15-M: INTENTOS DE APROXIMAR ÉTICA, POLÍTICA Y DEMOCRACIA
Oxímora. Revista Internacional de Ética y Política, 2013 En el 15-M confluyeron un conjunto heterogéneo de personas y grupos que dieron apoyo a lo que acabaría siendo una especie de plataforma o espacio de movilización que recogía distintas reivindicaciones, unas de carácter económico y social, y otras de naturaleza política.
Mir Garcia, Jordi, Prat Carvajal, Enric
openaire +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source