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Law Notes: St. Mary's University School of Law Newsletter Fall 2013

, 2013
2013 Distinguished Law Grads, Reflections on the Legacy of Service, Honoring Dean Cantu's Service to St.
St. Mary's University School of Law
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Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Identiteti hrvatskih raseljenika u zemljama njihova doseljavanja (15.–16. st.) [PDF]

, 2017
Dobrostojeći plemići su kao i velikaši Ugarsko- Hrvatskog Kraljevstva funkcionirali i na osnovi svojega društvenog položaja i na osnovi zemaljskog/županijskog uređenja države. Prihvaćanje elemenata novih osobnih identiteta (primjerice brakovima ili prilagođavanjem sustavima vrijednosti u novodoseljenim sredinama) bilo je, dakle, pravilom njihova ...
openaire   +1 more source

Law Notes: St. Mary's University School of Law Newsletter Fall 2008

, 2008
Culture Change: St. Mary's Students Work to Change Justice System, 2008 Distinguished Law Graduates Celebrated, Former Texas Supreme Court Justice Honored, Clinic Faculty Bolstered By New Talent, Law School Graduates 240, Rosas Mexican Government, In ...
St. Mary's University School of Law
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YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis

Medicina
Background and Objectives: Several biologics and oral Janus kinase (JAK) inhibitors have been developed and shown in clinical trials and real-world studies to be effective and safe in moderate-to-severe atopic dermatitis (AD).
Akihiro Horie, Tomomitsu Miyagaki, Chikako Hiranuma, Mami Iijima, Yoshiaki Hara, Shinya Oba, Mina Hashimoto, Reina Omori, Tatsuro Okano, Takafumi Kadono   +9 more
doaj   +1 more source

St. Cloud Tribune Vol. 16, No. 16, December 06, 1923

, 1923
Newspaper for St.
St. Cloud Tribune
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Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Law Notes: St. Mary's University School of Law Newsletter Spring 2008

, 2003
The China Connection: St. Mary's Partners with China's Top Law School, Texas Attorney General Grants Award to Law Clinic, Mock Trial Team at Nationals, New Scholarships for South Texas, Alumni Chapters Spring Up, Homecoming ...
St. Mary's University School of Law
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source