Results 81 to 90 of about 6,107,792 (298)

2014 St. Mary's University School of Law Homecoming CLE and Reunion Agenda

open access: yes, 2014
The schedule for the 2014 annual Homecoming CLE hosted by St.
St. Mary's University School of Law
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Chloroquine degradation in aqueous solution under electron beam irradiation

open access: yesNukleonika
Pharmaceutically active compounds are the most widely produced and consumed consumer products that pose a substantial threat to the environment and living organisms owing to their pharmacokinetics, side effects, and contraindications.
Kabasa Stephen   +3 more
doaj   +1 more source

2013 St. Mary's University School of Law Homecoming CLE and Reunion Agenda

open access: yes, 2013
The schedule for the 2013 annual Homecoming CLE hosted by St.
St. Mary's University School of Law
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Degradation of hydroxychloroquine in aqueous solutions under electron beam treatment

open access: yesNukleonika
Hydroxychloroquine (HCQ), a 4-amino quinoline derivative, has antimalarial and anti-inflammatory activity and was most recently proposed in the treatment of SARS-COVID-19.
Kabasa Stephen   +3 more
doaj   +1 more source

New Aspects of Resuscitation in Neurology and Neurosurgery

open access: yesОбщая реаниматология, 2014
The course of critical conditions in neurology and neurosurgery has specific features associated with the complex pathogen esis of brain injury, which in turn determines the specificity of resuscitation care.
K. A. Popugaev   +2 more
doaj   +1 more source

Law Notes: St. Mary's University School of Law Newsletter Spring 2012

open access: yes, 2012
St.
St. Mary's University School of Law
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Law Notes: St. Mary's University School of Law Newsletter Fall 2011

open access: yes, 2011
A Look at St. Mary's Legal Minds, On the Border: Legal Aid to the Underserved, Distinguished Law Graduate Award 2011, Kudos and Class Notes, In ...
St. Mary's University School of Law
core  

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