Comparison of the BioFire Joint Infection Panel to 16S Ribosomal RNA Gene-Based Targeted Metagenomic Sequencing for Testing Synovial Fluid from Patients with Knee Arthroplasty Failure. [PDF]
Azad MA+8 more
europepmc +1 more source
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan+12 more
wiley +1 more source
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng+9 more
wiley +1 more source
Analysis of the conformation of the 3′ major domain of Escherichia coli 16S ribosomal RNA using site-directed photoaffinity crosslinking [PDF]
Alexandre Montpetit+3 more
openalex +1 more source
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu+11 more
wiley +1 more source
Successful identification of Granulicatella adiacens in postoperative acute infectious endophthalmitis using a bacterial 16S ribosomal RNA gene-sequencing platform with MinION™: A case report. [PDF]
Ishino M+7 more
europepmc +1 more source
Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases.
Y. Doi, J. Wachino, Y. Arakawa
semanticscholar +1 more source
LncRNA TMEM99 Complexes with IGF2BP2 to Inhibit Autophagy in Lung Adenocarcinoma
LncRNA TMEM99 is significantly upregulated in lung adenocarcinoma (LUAD) and correlates with poor prognosis. It promotes LUAD cell proliferation, migration, and invasion while suppressing autophagy. Mechanistically, TMEM99 binds FUBP3 and recruits IGF2BP2 in an m⁶A‐dependent manner to stabilize and enhance p21 mRNA translation, uncovering a novel ...
Zhigang Wu+12 more
wiley +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu+16 more
wiley +1 more source