Results 111 to 120 of about 109,607,141 (279)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Physiological adaptation of two unicellular green algae to pH stress. [PDF]
, 1998 Two marine algae, Dunaliella parva and Chlorococcum submarinum were selected to study the effect of pH stress on single celled algae. D. parva has been well characterised physiologically, but not with regards to pH stress.
Howat, Judy I
core +2 more sources
Effects of Printing Layer Orientation on the High-Frequency Bending-Fatigue Life and Tensile Strength of Additively Manufactured 17-4 PH Stainless Steel. [PDF]
Materials (Basel), 2023 Ghadimi H +8 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Absorption of Nitrogen during Pulsed Wave L-PBF of 17-4 PH Steel. [PDF]
Materials (Basel), 2021 Brown B, Newkirk J, Liou F.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Manufacturing Elements with Small Cross-Sections of 17-4 PH Steel (1.4542) with the Application of the DMLS Additive Manufacturing Method. [PDF]
Materials (Basel), 2021 Budzik G +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
PH. SCHMALZ, ARCHITEKT, BAUGESCHÄFT, FRANKFURT A/M., HEINESTR. 17, FI 3642, NEUBAUTEN, UMBAUTEN, BAUGESUCHE, GUTACHTEN Ph. Schmalz, Architekt, Baugeschäft, Frankfurt a/M., Heinestr. 17, FI 3642, Neubauten, Umbauten, Baugesuche, Gutachten ( -
Ph. Schmalz
core
, 2013 Highly porous 17-4 PH stainless steel foam for implant applications was produced by space holder technique. Metal release and weight loss from 17-4 PH stainless steel foams were investigated in fluoride added artificial saliva environment by static ...
Mutlu, Ilven, Oktay, Enver
core +1 more source