Variations of Steroid Hormone Metabolites in Serum and Urine in Polycystic Ovary Syndrome after Nafarelin Stimulation: Evidence for an Altered Corticoid Excretion. [PDF]
To evaluate the clinical relevance of testing pituitary-ovarian responses in patients suffering from polycystic ovary syndrome (PCOS) with the GnRH agonist nafarelin, a 1.2-mg dose of nafarelin was given intranasally to 19 women with PCOS and 15 healthy ...
A. Lob +9 more
core +1 more source
Analysis of the Influencing Factors of 17-Hydroxyprogesterone Level and the Correlation between 17-Hydroxyprogesterone Level and the Clinical Parameters Related to Adrenal Cortical Function in Very-Low-Birth-Weight Infants [PDF]
Purpose 17-Hydroxyprogesterone (17-OHP) screening results are difficult to interpret owing to the many influencing factors, and confirming the test results takes time.
Chang Dae Kum +5 more
doaj +1 more source
Correlation of ovarian volume and clinical and laboratory parameters of PCOS in Korean patients
Background: The aim of this study is to analyze the correlation of ovarian volume and clinical and laboratory parameters of polycystic ovary syndrome (PCOS) in Korean women. Methods: Two hundred and thirty-three patients aged between 20 and 40 years with
Seul Yi Lee +3 more
doaj +1 more source
Progestogens for maintenance tocolysis in symptomatic women. A systematic review and meta-analysis.
ObjectivePrevention of preterm birth (PTB) with progestogens after an episode of threatened preterm labour is still controversial. As different progestogens have distinct molecular structures and biological effects, we conducted a systematic review and ...
Francesca Ferrari +4 more
doaj +2 more sources
Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]
Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
A Shennan +37 more
core +5 more sources
Manipulating CD4+ T Cell Pathways to Prevent Preeclampsia
Preeclampsia (PreE) is a placental disorder characterized by hypertension (HTN), proteinuria, and oxidative stress. Individuals with PreE and their children are at an increased risk of serious short- and long-term complications, such as cardiovascular ...
Eileen J. Murray +9 more
doaj +1 more source
Oral progesterone for the prevention of recurrent preterm birth: systematic review and metaanalysis [PDF]
Objective The purpose of this study was to perform a systematic review and metaanalysis of randomized controlled trials on oral progesterone compared with placebo or other interventions for preterm birth prevention in singleton pregnancies with ...
Ashoush, Sherif +6 more
core +1 more source
Progesterone after previous preterm birth for prevention of neonatal respiratory distress syndrome (PROGRESS): a randomised controlled trial [PDF]
Background: Neonatal respiratory distress syndrome, as a consequence of preterm birth, is a major cause of early mortality and morbidity during infancy and childhood. Survivors of preterm birth continue to remain at considerable risk of both chronic lung
Jodie M Dodd +52 more
core +2 more sources
Dehydroxylation of 16 alpha-hydroxyprogesterone by fecal flora of man and rat
16 alpha-Hydroxyprogesterone, precursor of biliary 16 alpha-hydroxypregnanolone, was incubated with mixed fecal flora of humans and rats. The major steroid metabolite formed in both systems was 3 alpha-hydroxy-17 alpha-pregnan-20-one.
V D Bokkenheuser +4 more
doaj +1 more source
Gestational age at initiation of 17-alpha hydroxyprogesterone caproate and recurrent preterm birth [PDF]
Background Preterm birth is the leading cause of neonatal morbidity and mortality in nonanomalous neonates in the United States. Women with a previous early spontaneous preterm birth are at highest risk for recurrence.
Dotters-Katz, S.K. +4 more
core +2 more sources

