Results 61 to 70 of about 3,749 (163)

Lack of Influence of the Androgen Receptor Gene CAG-Repeat Polymorphism on Clinical and Electrocardiographic Manifestations of the Brugada Syndrome in Man

Clinical Medicine Insights: Cardiology, 2012
Background Clinical studies suggest that testosterone (T) plays an important role in the male predominance of the clinical manifestations of the Brugada syndrome (BS). However, no statistically significant correlations have been observed between T levels
S. Mariani, B. Musumeci, S. Basciani, D. Fiore, P. Francia, A. Persichetti, M. Volpe, C. Autore, C. Moretti, S. Ulisse, L. Gnessi   +10 more
doaj   +1 more source

Physiological and Behavioural Characterisation of a Novel Steroid Sulfatase‐Deficient Mouse

Genes, Brain and Behavior, Volume 25, Issue 4, August 2026.
STS‐deficient mice are grossly healthy and breed as expected, but are mildly hyperactive and have heavier hearts compared with sex‐matched wildtype controls. ABSTRACT Steroid sulfatase (STS) cleaves sulphate groups from steroid hormones. In humans, STS deficiency is associated with X‐linked ichthyosis, an increased predisposition to neurodevelopmental ...
Trevor Humby, Freya R. Shepherd, Talia Elgie, Libby Anderson‐Watkins, Lucy I. Beevors, Angela E. Taylor, Paul A. Foster, William Davies   +7 more
wiley   +1 more source

Progesterone therapy for prevention of recurrent spontaneous preterm birth in a minority patient population: a retrospective study

BMC Pregnancy and Childbirth
Background Preterm birth is a leading cause of infant morbidity and mortality worldwide. The burden of prematurity underscores the need for effective risk reduction strategies. The purpose of this study is to evaluate the efficacy of progesterone therapy,
Genevieve R. Mazza, Emi Komatsu, Madeline Ponzio, Claire Bai, Victoria K. Cortessis, Elizabeth B. Sasso   +5 more
doaj   +1 more source

Genetically Confirmed Osteogenesis Imperfecta (COL1A1) With Unexplained Ambiguous Genitalia in a 46,XY Child: An Index Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
A 6‐year‐old child with a rare dual diagnosis confirmed by genetic testing ‐ osteogenesis imperfecta (blue sclerae, disproportionate short stature) and concurrent 46,XY disorder of sex development (micropenis, hypospadias, impalpable gonads). ABSTRACT Osteogenesis imperfecta (OI) is a heritable disorder of type I collagen characterized by bone ...
Harshita Agarwal, Tathagata Jha, Mohammad Orooj Azmi, Soumita Sarkar, Vinay Suresh   +4 more
wiley   +1 more source

Evaluation of Adrenal Volume with Spiral Computed Tomography and Plasma Androgens in Hirsute Women Without Polycystic Ovaries

Endocrinology Research and Practice, 2022
We investigated the relation between the androgens and adrenal gland volume (AV), which has been suggested as an indicator of corticotropin, related adrenal activity, in 29 hirsute women without polycystic ovary syndrome and 11 healthy women.
Rüştü Serter, Serdar Güler, Işıl Tunçbilek, Can Karaman, Necdet Ünüvar, Gül Gürsoy   +5 more
doaj   +2 more sources

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, Volume 4, Issue 2, June 2026.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

Identification of the Steroids in Neonatal Plasma that Interfere with 17 Alpha-Hydroxyprogesterone Radioimmunoassays

Clinical Chemistry, 1992
Abstract Neonatal plasma contains interferents that increase the apparent 17 alpha-hydroxyprogesterone (17-OHP) content measured by direct (no-extraction) radioimmunoassay. We fractionated extracts from neonatal plasma pools by liquid chromatography with a Sephadex LH-20 column and measured 17-OHP immunoreactivity by a direct test kit ...
T, Wong, C H, Shackleton, T R, Covey, G, Ellis   +3 more
openaire   +2 more sources

Progesterone for the prevention of preterm birth: indications, when to initiate, efficacy and safety

Therapeutics and Clinical Risk Management, 2008
Helen Y How, Baha M SibaiDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati, Cincinnati, OH USAAbstract: Preterm birth is the leading cause of neonatal mortality and morbidity and long-term disability ...
Helen Y How, Baha M Sibai
doaj  

Immunomodulatory Role of Natural Progesterone in Pregnancy: A Review

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 6, June 2026.
ABSTRACT Aim Pregnancy complications such as miscarriage, preterm birth (PTB), and luteal phase defects (LPD) are significant reproductive health issues globally, with both physical and psychological implications. This review aims to examine the role of natural progesterone in pregnancy‐related disorders, specifically threatened and recurrent ...
Prakash Mehta, Hemant Deshpande, Anjali Deshpande, Reshma Quadros, Shruti Dharmadhikari, Chintan Khandhedia, Gaurav Puppalwar, Amey Mane, Suyog Mehta   +8 more
wiley   +1 more source

Adrenal Biomarkers of Stress in Transgender and Gender‐Diverse Adolescents

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Transgender and gender diverse (TGD) adolescents are frequently exposed to minority stress, which may influence the hypothalamic–pituitary–adrenal (HPA) axis during critical developmental windows. Altered cortisol dynamics have been described in populations facing chronic stress, yet evidence in TGD youth is limited.
Simone Coslovich, Stefania Tonetto, Giulia Bragato, Gianluca Tamaro, Alice Fachin, Paolo Dalena, Lorenzo Zandonà, Antonella Fabretto, Egidio Barbi, Gianluca Tornese   +9 more
wiley   +1 more source