Evaluating the prognostic significance of the pre-treatment neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios in <sup>177</sup>Lu-DOTATATE PRRT treated patients with advanced metastatic neuroendocrine tumors. [PDF]
Padwal MK +4 more
europepmc +1 more source
177Lu-DOTATATE Theranostics [PDF]
Purpose Pretreatment predictions of absorbed doses can be especially valuable for patient selection and dosimetry-guided individualization of radiopharmaceutical therapy. Our goal was to build regression models using pretherapy 68Ga-DOTATATE PET uptake data and other baseline clinical factors/biomarkers to predict renal ...
Avery B, Peterson +6 more
openaire +3 more sources
177Lu-DOTATATE Tedavi Sonucunu Öngören Faktörlerin Belirlenmesi
Amaç: 177Lu-DOTATATE tedavisi alan hastalarda tedaviye sonucunu öngörenfaktörlerin belirleyerek tedaviden fayda görmesi beklenen hastalarınseçiminde bu faktörlerden yararlanılmasını sağlamaktır.Yöntem: Merkezimizde 2015-2023 yılları arasında 177Lu-DOTATATEtedavisi uygulanan hastalar retrospektif olarak değerlendirildi.
Karahan Şen, Nazlı Pınar +3 more
core +3 more sources
p53 stabilisation potentiates [177Lu]Lu-DOTATATE treatment in neuroblastoma xenografts
Purpose Molecular radiotherapy is a treatment modality that is highly suitable for targeting micrometastases and [177Lu]Lu-DOTATATE is currently being explored as a potential novel treatment option for high-risk neuroblastoma.
David P. Lane +2 more
exaly +2 more sources
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Abstract We represent the case of a 61-year-old man with atypical carcinoid tumor of the lung. On posttherapy 177Lu-DOTATATE whole-body scan, focal intense uptake in the inferomedial side of the liver was detected. Pretherapy 68Ga-DOTATATE PET/CT showed no sign of liver metastasis, and posttherapy diagnostic dynamic liver MRI is used to ...
Mine, Araz +4 more
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Description of the methodology for dosimetric quantification in treatments with 177Lu-DOTATATE
Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), 2021Implementation of dosimetry calculations in the daily practice of Nuclear Medicine Departments is, at this time, a controversial issue, partly due to the lack of a standardized methodology that is accepted by all interested parties (patients, nuclear medicine physicians and medical physicists).
T, Monserrat Fuertes +6 more
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Rapid Progression After 177Lu-DOTATATE in Patients With Neuroendocrine Tumors
Pancreas, 2021Abstract Peptide receptor radionuclide therapy (PRRT) is a treatment option for somatostatin receptor–positive, unresectable or metastatic neuroendocrine tumors (NETs). Despite high disease control rates seen with PRRT, a subset of the NET population seems to have a short progression-free interval.
Hussein A, Assi +5 more
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Evaluation of Patient Transmission Factor Following the Administration of 177Lu-DOTATATE
Health Physics, 2022Abstract 177Lu-DOTATATE is a radionuclide therapy that is FDA approved for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors. Treatment facilities are required to determine the maximum radiation dose from such subjects to the maximally exposed member of the public ...
Kimyli, Recca +5 more
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Increased 177Lu-DOTATATE Uptake in Paget Disease
Clinical Nuclear Medicine, 2013A 45-year-old female patient was referred for peptide receptor radionuclide therapy of liver metastases of neuroendocrine origin; the patient had undergone 2 years earlier surgical resection of a grade 2 neuroendocrine neoplasm of ampulla of Vater infiltrating the duodenal submucosa and muscular layers and the neighboring pancreatic tissue.
MINUTOLI, Fabio +4 more
openaire +3 more sources
Incidental Muscle Uptake of 177Lu-DOTATATE in Peripheral Vascular Disease
Nuclear Medicine and Molecular Imaging, 2021Somatostatin receptor (SSTR)-based imaging and therapy has emerged as well-established modality in neuroendocrine tumors. However, its role in inflammation imaging is still evolving. We present a 48-year-old male with metastatic neuroendocrine tumor who underwent lutetium-177-based somatostatin receptor-based therapy.
Piyush Aggarwal +5 more
openaire +2 more sources

