Results 131 to 140 of about 309,135 (337)

The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth

Nature Communications, 2016
Dysfunctions in ribosome biogenesis cause developmental defects and increased cancer susceptibility; however, the connection between ribosome assembly and tumorigenesis remains unestablished.
Dongmei Bai, Jinfang Zhang, Tingting Li, Runlai Hang, Yong Liu, Yonglu Tian, Da Wei Huang, Linglong Qu, Xiaofeng Cao, Jiafu Ji, Xiaofeng Zheng   +10 more
semanticscholar   +1 more source

40S ribosome biogenesis co-factors are essential for gametophyte and embryo development

, 2013
Ribosome biogenesis is well described in Saccharomyces cerevisiae. In contrast only very little information is available on this pathway in plants. This study presents the characterization of five putative protein co-factors of ribosome biogenesis in ...
Roman Martin, Martin, Roman, Roman Martin (85483), Simm, Stefan, Markus T. Bohnsack, Markus T Bohnsack, Benjamin L. Weis (277837), Stefan Simm, Sandra Missbach (277836), Markus T. Bohnsack (277840), Benjamin L Weis, Enrico Schleiff, Weis, Benjamin L., Sandra Missbach, Bohnsack, Markus, Mißbach, Sandra, Stefan Simm (277838), Schleiff, Enrico, Enrico Schleiff (49377), Lafontaine, Denis, Bohnsack, Markus T., Ra Missbach, Benjamin L. Weis   +22 more
core   +1 more source

Oligonucleotide primers used for the 18s rRNA amplification.

, 2022
Oligonucleotide primers used for the 18s rRNA amplification.
Enoch Aninagyei (5940794), Tanko Rufai (13919648), Adjoa Agyemang Boakye (12837281), Clement Okraku Tettey (11883388), Kofi Adjei Ntiri (13919636), Samuel Ohene Ofori (13919639), Comfort Dede Tetteh (13919642), Thelma Teley Aphour (13919645)   +7 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

A comparative phylogenetic analysis of Theileria spp. by using two "18S ribosomal RNA" and "Theileria annulata merozoite surface antigen" gene sequences

Archives of Razi Institute, 2013
More than 185 species, strains and unclassified Theileria parasites are categorized in the Entrez Taxonomy. The accurate diagnosis and proper identification of the causative agents are important for understanding the epidemiology, prevention and ...
Habibi, G.
doaj  

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

The Expansion Segments of 28S Ribosomal RNA Extensively Match Human Messenger RNAs

Frontiers in Genetics, 2018
Eukaryote ribosomal RNAs (rRNAs) have expanded in the course of phylogeny by addition of nucleotides in specific insertion areas, the expansion segments.
Michael S. Parker, Ambikaipakan Balasubramaniam, Floyd R. Sallee, Steven L. Parker   +3 more
doaj   +1 more source

Miscleaved 18S rRNA are rare in vivo.

(A, B) 3′-RACE-sequencing of 18S rRNA extracted from 40S subunits purified from Gal::Pno1;Gal::Dim1 cells grown in glucose to deplete endogenous Pno1 and Dim1 and supplemented with plasmids encoding Pno1 and Dim1-E85A, an inactive mutant that prevents ...
Elise S. Brunk (18447335), Adam J. Getzler (18447338), Katrin Karbstein (232578), Melissa D. Parker (8124692)   +3 more
core   +1 more source

Neighbor-joining phylogenetic tree based on 18S rRNA sequences.

, 2022
Neighbor-joining phylogenetic tree based on 18S rRNA sequences.
Yanli Wei (1791124), Naijiang Chen (13924391), Jing Li (10611), Jinhu Wang (2631772), Jinna Zhou (13924394), Junyu Chen (4263742), Qiangying Zhang (5051219), Duo Bu (5840261)   +7 more
core   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source