Results 281 to 290 of about 77,981 (327)

High-throughput triazole-based combinatorial click chemistry for the synthesis and identification of functional metal complexes. [PDF]

Nat Commun
Husbands DR, Özsan Ç, Welsh A, Gammons RJ, Frei A.   +4 more
europepmc   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Enhanced Cooperative Lithium Halide Recognition by Heteroditopic Halogen Bonding (XB) Macrocycles. [PDF]

Inorg Chem
Khianjinda T, Vigromsitdet S, Srisawat P, Sawektreeratana N, Tantirungrotechai J, Sukwattanasinitt M, Harding DJ, Beer PD, Tantirungrotechai Y, Bunchuay T.   +9 more
europepmc   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy - a literature review. [PDF]

RSC Adv
Khasawneh HEN, Hassan HM, Alharbi AA, Almagharbeh WT, Al-Aouadi RFA, Kaur K, Maranan R, Farhan HM, Hashem H, Hassan MM, Bräse S, Al-Emam A.   +11 more
europepmc   +1 more source

Screen ammonium‐based deep eutectic solvents for CO2 capture: Extended UNIFAC‐DES, calibrated COSMO‐RS, and experiment

AIChE Journal, Volume 72, Issue 2, February 2026.
Abstract CO2 solubility in deep eutectic solvent (DES) is a critical property to indicate the competence of using DESs for carbon capture. This work presents a systematic screening framework with computational and experimental procedures to identify the promising ammonium‐based DESs for CO2 absorption.
Hao Qin, Xiang Zhang, Jiawei Ruan, Kai Sundmacher   +3 more
wiley   +1 more source

Mechano-Induced Synthesis of Polyethylene Glycols α,ω-DiSubstituted with 4-(PAH)-1<i>H</i>-1,2,3-Triazoles in Presence of <i>In Situ</i>-Generated Bronze Microparticles as Catalyst. [PDF]

Molecules
Mohammed MS, Kovalev IS, Platonov VA, Santra S, Wang Z, Zyryanov GV, Charushin VN.   +6 more
europepmc   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

A Systematic Review on the Toxicology of European Union-Approved Triazole Fungicides in Cell Lines and Mammalian Models. [PDF]

J Xenobiot
Vulpe CB, Iachimov-Datcu AD, Pujicic A, Agachi BV.   +3 more
europepmc   +1 more source

Disseminated Invasive Aspergillosis in a Young Patient With Chronic Alcohol Use and Seemingly Preserved Immunocompetence: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Invasive aspergillosis, though typically seen in immunocompromised patients, can also affect immunocompetent individuals and mimic pulmonary malignancy. This case highlights the importance of considering fungal infections in the differential diagnosis of chronic respiratory symptoms, particularly in patients with risk factors such as heavy ...
Kumail Khandwala, Hiba Sawliha Syed, Shayan Sirat Maheen Anwar, Sehar Suleman, Khabab Abbasher Hussien Mohamed Ahmed   +4 more
wiley   +1 more source