Results 131 to 140 of about 25,343 (252)

Combining Laser‐Induced Edition to Collision‐Induced Sequencing of Digital Oligomers in a Single Gas‐Phase Experiment

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale To increase the confidentiality level of molecular tags, binary information can be hidden in sequence‐defined oligomers using isobaric monomers including a photo‐sensitive one, which mass can be modified upon light irradiation. Reading such secured data requires light edition prior to MS/MS sequencing, which was investigated here in ...
Clothilde Comby‐Zerbino, Jean‐François Lutz, Luke MacAleese, Laurence Charles   +3 more
wiley   +1 more source

Synthesis, Physical and Ion-Conducting Properties of 1,2,3-Triazolium Ionic Liquids. [PDF]

Molecules
Abdelhedi Miladi I, Chikhaoui M, Alaa Eddine M, Serghei A, Ben Romdhane H, Drockenmuller E.   +5 more
europepmc   +1 more source

Electrochemical investigation of radical‐radical recognition in viologen‐based ditopic structures

Responsive Materials, EarlyView.
The so‐called “blue box” is one of the most studied macrocycles. Yet, functionalized macrocycles of this type are rarely investigated. This work describes the radical‐radical recognition properties of ditopic structures, including functionalized blue‐box macrocycles.
Ahmad Bachir, Fabiana Ciocchetti, Caterina Baccini, Sayed Suliman Shah, Andrea Secchi, Cristian Pezzato, Giulio Ragazzon   +6 more
wiley   +1 more source

Prevalence of cyp51A variants in a US collection of Aspergillus fumigatus clinical isolates and comparative analysis of their contribution to triazole antifungal resistance. [PDF]

J Antimicrob Chemother
Gómez Londoño LF, Souza ACO, Burt B, Das S, Ge W, Meza-Perez V, Wiederhold NP, Shelat AA, Cuomo CA, Fortwendel JR, Rogers PD.   +10 more
europepmc   +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

Small, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre, Elisabeth Mayerhoefer, Julia Puck, Himalaya Parajuli, Lorena Larios Salazar, Paul Johan Høl, Ridhima Das, Patrick Roth, Christian Arvei Moen, Ulrich Schatzschneider, Line Bjørge, Daniela Elena Costea, Anke Krueger   +12 more
wiley   +1 more source

Rescuing TP53 from nonsense: novel triazoles for translational readthrough via optimized drug design. [PDF]

Sci Rep
Ricci D, Menditto M, Culletta G, Tutone M, Rizzo C, Pace A, Lentini L, Pibiri I.   +7 more
europepmc   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

The Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros, Livia C. L. Valente, Thiago Barcellos, Daniela Hartwig, Laura Abenante, Eder J. Lenardão   +5 more
wiley   +1 more source

Effect of antifungal triazoles on vinca alkaloid neurotoxicity in pediatric patients: A retrospective case series analysis and literature review. [PDF]

Medicine (Baltimore)
Zhao Y, Ren X, Chen J, Zhu Y, Guo N, Zhang X, Huang L.   +6 more
europepmc   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source