Results 271 to 280 of about 38,585 (330)

Agricultural propiconazole residues promote triazole cross-resistance in <i>Cryptococcus neoformans</i> through <i>ERG11</i> and efflux pump overexpression. [PDF]

Antimicrob Agents Chemother
Yu H, Peng W, Li H, Zhang Y, Fu X, Gong X, Wei H, Zhou Q, Huang Y, Cao D.   +9 more
europepmc   +1 more source

Síntesis de 1,2,3-Triazoles Catalizada por un Complejo Bistriazolli de Cobre (I) [PDF]

, 2013
Cuevas Yañez, Erick, Segura Arzate, Jesús   +1 more
core  

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Optimizing antifungal dosing for invasive <i>Cryptococcus</i> infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010-2023 Antimicrobial Testing Leadership and Surveillance data. [PDF]

Front Pharmacol
Liu CY, Lai CC, Hsueh CC, Weng CJ, Chang WL, Hsueh PR, Jean SS.   +6 more
europepmc   +1 more source

Etude sur les conditions de réintroduction des fongicides systémiques dans les programmes de lutte contre la maladie des raies noires au Cameroun dans la zone de prodcution de la banane dessert d'exportation : rapport narratif final N°9 décembre 2010 [PDF]

, 2010
Careel, Françoise, Carlier, Jean, De Lapeyre de Bellaire, Luc, Ngando Essoh Otto, Josué, Ravigné, Virginie, Rieux, Adrien, Zapater, Marie-Françoise   +6 more
core  

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Macrocycles are effective molecular glues to stabilize the 14‐3‐3/ChREBP interaction. Linker length modulation uncovered an inverse correlation between the macrocycle binding affinity to 14‐3‐3 and its cooperativity in 14‐3‐3/ChREBP stabilization.
Marloes A. M. Pennings, Merel A. W. van den Bosch, Ansgar Oberheide, Carlo J. A. Verhoef, Christian Ottmann, Albert J. Markvoort, Galen P. Miley, Luc Brunsveld   +7 more
wiley   +2 more sources

Triazole-(<i>p</i>-tolylthio)methyl hybrids <i>via</i> click chemistry: synthesis, molecular docking, and evaluation as promising anticancer candidates. [PDF]

RSC Adv
El Malah T, El-Rashedy AA, Abdel-Mageid RE, Rashad AE, Soliman HA, Awad HM, Shamroukh AH.   +6 more
europepmc   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Triazoles synthesis using nanocatalyst triazine-pyrimidine-modified cobalt-based metal-organic frameworks. [PDF]

Nanoscale Adv
Amirian M, Ghorbani-Vaghei R, Alavinia S.   +2 more
europepmc   +1 more source