Results 51 to 60 of about 4,584,770 (187)

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles

Molecules, 2001
A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans.
Aleksandra Buzarovska, Dora Gabor Molnar, Vlado Kakurinov, Vesna Dimova, Katica Colanceska-Ragenovic   +4 more
doaj   +1 more source

Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]

, 2016
Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core   +3 more sources

Computationally motivated synthesis and enzyme kinetic evaluation of N-(β-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors [PDF]

, 2015
Following our recent study of N-(β-D-glucopyranosyl)-oxadiazole-carboxamides (Polyák et al., Biorg. Med. Chem. 2013, 21, 5738) revealed as moderate inhibitors of glycogen phosphorylase (GP), in silico docking calculations using Glide have been performed ...
Alex, Arunan, Benltifa, Bokor, Broggini, Brownlee, Carta, Cheng, Cho, Chrysina, Condi, Danaei, Docsa, Fischer, Francl, Friesner, Hayes, Hayes, Hehre, Huisgen, Huisgen, Huisgen, Jorgensen, Jorgensen, Kaminski, Kantsadi, Kantsadi, Kenny, Koldobskii, Kun, Lagorce, Lipinski, Lonsdale, Marten, Murray, Murray, Nagy, Nagy, Oikonomakos, Paolini, Polya, Polyák, Pospisil, Potts, Potts, Smith, Somsák, Somsák, Somsák, Somsák, Still, Tannor, Veber, Woon, Zhao, Zhong, Zhou, Ősz   +57 more
core   +1 more source

Synthesis and physical-chemical properties of 3-(alkylthio)-4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Selection, synthesis and biological properties of new compound play major role in creating original medicines. Methods and results. Therefore, to find new bioactive compounds 3-(alkylthio)-4-R-5-(thiophene-2-ylmethyl)-4H-1,2,4-triazoles, where R -
O. A. Suhak, O. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source

Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo

Фармацевтичний журнал, 2018
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
doaj   +1 more source

Synthesis of 1,2,3-triazole functionalized hyperbranched poly(ethyleneimine) and its use as multifunctional anionic macroinitiator for diglycidyl ether of bisphenol A curing [PDF]

, 2016
Hyperbranched poly(ethyleneimine) (PEI) has been modified by the addition of propargyl acrylate following a Michael addition reaction. On this polymer (PEI-yne) a copper (I)-catalyzed azide alkyne cycloaddition (CuAAC) has been performed to obtain a ...
Acebo Gorostiza, Cristina, Appelhans, Dietmar, Lederer, Albena, Ramis Juan, Xavier, Serra Albet, Àngels   +4 more
core   +2 more sources

Design, synthesis and screening of indole acetic acid-based tri-azo moieties as antioxidants, anti-microbial and cytotoxic agents

Frontiers in Pharmacology, 2023
Multidrug resistance and infectious disease have enormous spread despite drug discovery and development advancements. 1, 2, 4 -triazoles have been extensively studied, playing an imperative role in many pathologic conditions.
Maryam Javaid, Ihsan-Ul Haq, Humaira Nadeem, Humaira Fatima, Arif-Ullah Khan, Nadeem Irshad   +5 more
doaj   +1 more source

1,2,4-TRIAZOLES: SYNTHETIC STRATEGIES AND PHARMACOLOGICAL PROFILES [PDF]

, 2014
Multicomponent, solid-phase, microwave and grinding methods are the constructive modes in the sustainable synthesis of 1, 2, 4-triazoles and such reactions have attracted enormous interest in recent years.
B., Namratha, Gaonkar, Santosh L.
core  

Synthesis, Characterization and Antimicrobial Activity of Cu(II), Co(II) and Ni(II) Complexes with O, N, and S Donor Ligands

E-Journal of Chemistry, 2008
The complexes of the type ML2 [where M = Cu(II), Co(II), and Ni(II)] L = 1-phenyl-1-ene-3-(2-hydroxyphenyl)-prop-2-ene with 3- substituted-5-mercapto-4-amino-1,2,4-triazoles.
Vidyavati Reddy, Nirdosh Patil, S. D. Angadi   +2 more
doaj   +1 more source

Analysis of the relationship between the predicted biological activity and the chemical structure of S-derivatives of 5-(5-bromofuran-2-yl)-4R-1,2,4-triazole-3-thiols

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
1,2,4-Triazole derivatives are actively used as components in the development of new drugs, plant protection products, polymeric materials, anti-corrosion agents and etc.
O. A. Bigdan
doaj   +1 more source