Results 101 to 110 of about 220,097 (316)

Expression, purification and characterization of the HIV-1 coreceptor CCR5 and its ligand RANTES and high-pressure NMR investigation of hydrogen bonds in biomolecules [PDF]

, 2010
Nuclear magnetic resonance spectroscopy is a very versatile technique for the investigation of biomolecular structures and dynamics. In this thesis, solution and solid state NMR methods have been applied to study a membrane protein and its interactions ...
Nisius, Lydia
core   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results

, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Madan Rehani, Rakesh Sharma, Arun Agrawala   +2 more
core  

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Cytosine ribose flexibility in DNA : a combined NMR 13C spin relaxation and molecular dynamics simulation study

, 2008
Using (13)C spin relaxation NMR in combination with molecular dynamic (MD) simulations, we characterized internal motions within double-stranded DNA on the pico- to nano-second time scale.
Elke Duchardt, Nilsson, Lennart, Duchardt, Elke, Schleucher, Jürgen,, Duchardt-Ferner, Elke, Schleucher, Jürgen, Lennart Nilsson, Jürgen Schleucher   +7 more
core   +1 more source

Applications of quantitative 13C NMR in pharmaceutical analysis: From small molecule drugs to biopolymers

Journal of Pharmaceutical Analysis
Chemical integrity is indispensable for advancing healthcare by ensuring the availability of high quality, safe, and effective pharmaceutical products. Ingredient quantification is particularly pivotal in this process.
Qi Tang, Sinan Wang, Xiongqi Zhai, Seon Beom Kim, Prabhakar Achanta, Gonzalo R. Malca-Garcia, Yuzo Nishizaki, Yi Wang, Yu Tang   +8 more
doaj   +1 more source

Chiral Phosphoric Acid Promoted Chiral 1H NMR Analysis of Atropisomeric Quinolines. [PDF]

Front Chem, 2021
Wan J, Jiang J, Li J.
europepmc   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Synthesis and complete NMR spectral assignments of new benzylamino coumarin derivative [PDF]

Bulletin of Natural Sciences Research, 2020
This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield.
Dekić Vidoslav, Radulović Niko, Ristić Milenko, Dekić Biljana, Ristić Novica   +4 more
doaj  

Quantitative 1H-NMR analysis reveals steric and electronic effects on the substrate specificity of benzoate dioxygenase in Ralstonia eutropha B9. [PDF]

J Ind Microbiol Biotechnol, 2022
Bent JS, Clark ZT, Collins JA.
europepmc   +1 more source