Results 81 to 90 of about 190 (131)

Novel Preparation of 2,1‐Benzothiazine Derivatives from Sulfonamides with [Hydroxy(tosyloxy)iodo]arenes.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Yuhta, Misu, Hideo, Togo
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AN IMPROVED SYNTHESIS OF 3,4-DIHYDRO-1H-2,1-BENZOTHIAZIN-4-ONE 2,2-DIOXIDE

Organic Preparations and Procedures International, 1971
Abstract Utilizing polymer-bound anthranilic acid derivatives, we were able to obtain 3,4-dihydro-1H-2,1-benzothiazine-4-one 2,2-dioxide derivatives through N-methanesulfonylation by use of sulfonyl chloride, sulfonic acid, or sodium sulfonate, N-alkylation under Mitsunobu condition, and the cyclative cleavage in 8–52% five-step overall isolated ...
J. G. Lombardino, N. W. Treadway
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1,2- and 2,1-Benzothiazines and Related Compounds

1981
Publisher Summary The chapter focuses primarily on the two ring systems 1 and 2 and their oxidized derivatives. A few related ring systems, such as dibenzo- and hetero ring-fused 1,2-thiazines are included where it appears appropriate because of similar chemistry or analogous utility to the benzothiazine compounds. This chapter brings together all of
J.G. Lombardino, D.E. Kuhla
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Synthesis and Herbicidal Activity of 3-Acetyl-4-hydroxy-2,1-benzothiazine Derivatives

Chemical Research in Chinese Universities, 2019
In order to develop a novel herbicide containing the 2,1-benzothiazine motif, a series of 3-acetyl-4-hydroxy-2,1-benzothiazine derivatives was synthesized. All the target compounds were confirmed by 1H NMR, 13C NMR, and high-resolution mass spectrometry(HRMS).
Kang Lei, Yang Liu, Shiben Wang, Bin Sun, Xuewen Hua, Xiaohua Xu   +5 more
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Synthesis, single crystal X-ray, spectroscopic and computational (DFT) studies 2,1-benzothiazine based hydrazone derivatives

Journal of Molecular Structure, 2021
Abstract 2,1-Benzothiazine-4(3H)-one 2,2-dioxide was synthesized through a multistep procedure starting with methyl anthranilate. It was reacted with hydrazine monohydrate to form corresponding hydrazine derivative which was subsequently treated with acetone and cyclopentanone respectively to get benzothiazine based hydrazones.
Shakeel Ahmad, Tariq Mahmood, Matloob Ahmad, Muhammad Nadeem Arshad, Faizan Ullah, Muhammad Shafiq, Sana Aslam, Abdullah M. Asiri   +7 more
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A convenient synthesis of 3,4-dihydro-2,2-dioxide 5-hydroxy-2,1-benzothiazine

Tetrahedron Letters, 1994
Abstract 3-methoxy-2-methyl-aniline 3 is converted to the benzothiazine-dioxide 1 in a 7-steps procedure: the key transformation being the cyclization of an ortho-functionnalized N-benzyl sulfonanilide.
Dominique Blondet, Jean-Claude Pascal
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Synthesis, antiinflammatory, and cytotoxic activity of novel pyrazolo[4,3‐c][2,1]benzothiazine 4,4‐dioxide derivatives

Journal of Heterocyclic Chemistry, 2022
Abstract13 novel pyrazolo[4,3‐c][2,1]benzothiazine 4,4‐dioxide derivatives that mimic the pharmacophore of piroxicam as well as celecoxib were conveniently synthesized in a catalyst‐free and atom‐economical method in which an unconventional redox‐neutral reaction of 2‐nitrochalcones with elemental sulfur to straightforward access to 2,1‐benzothiazine 2,
Ngoc Binh Vo, Quoc Anh Ngo
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Recent advancement in the synthesis of 1,2- and 2,1-benzothiazines

Synthetic Communications, 2018
1,2- and 2,1-benzothiazines, for example, 1,2-benzothiazine-1,1-dioxides. 2,benzothiazine-2,2-dioxides, 1-alkyl/aryl-1,2-/2,1-benzothiazine-S-oxides, dibenzothiazine and polyheterocycle containing ...
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Chapter 1 Recent progress in the chemistry of 2,1-benzothiazines

2008
Publisher Summary This chapter discusses the progress of synthetic procedures and applications of 2,1-benzothiazines and related compounds. Togo's group reported the preparation of the 2,1-benzothiazines via an ionic pathway with hypervalent iodine compounds.
Xuechuan Hong, Michael Harmata
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Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

European Journal of Medicinal Chemistry, 2018
Over recent years, many RNA viruses have been "re-discovered", including life-threatening flaviviruses, such as Dengue, Zika, and several encephalitis viruses. Since no specific inhibitors are currently available to treat these infections, there is a pressing need for new therapeutics.
Rolando Cannalire, Delia Tarantino, Andrea Astolfi, Maria Letizia Barreca, Stefano Sabatini, Serena Massari, Oriana Tabarrini, Mario Milani, Gilles Querat, Eloise Mastrangelo, Giuseppe Manfroni, Violetta Cecchetti   +11 more
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