Molecular imprinting for neurology: Materials, applications, and limitations
Ibrain, Volume 12, Issue 1, Page 3-37, Spring 2026.Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
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Water-promoted dehydrative coupling of 2-aminopyridines in heptane via a borrowing hydrogen strategy. [PDF]
RSC Adv, 2021 Nakayama T +3 more
europepmc +1 more source
Equine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
, 2012 dissertationTransition metal catalyzed [2+2+2] cycloaddition reactions are an important class of reactions that provide the means for the rapid construction of various carbocyclic and heterocyclic compounds.
D'Souza, Brendan Roberto
core
Exploring the use of dalfampridine (4‐aminopyridine) for treatment of ataxia in cerebellar stroke
PM&R, EarlyView.
Arjun Kotwal +4 more
wiley +1 more source
Direct‐to‐Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery
ChemMedChem, Volume 21, Issue 4, 25 February 2026.Crude yet clever: Direct‐to‐biology workflows exploit nanoscale synthesis and plate‐based assays to accelerate hit discovery, save precious intermediates, and rethink early drug discovery. Direct‐to‐biology (D2B) has emerged as a transformative concept in early drug discovery, defined by the direct on‐target screening of crude reaction mixtures without
Ariane F. Hübner, Fabian Barthels
wiley +1 more source
Nitric oxide synthases (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
, 2019 Nitric oxide synthases (NOS, E.C. 1.14.13.39) are a family of oxidoreductases that synthesize nitric oxide (NO.) via the NADPH and oxygen-dependent consumption of L-arginine with the resultant by-product, L-citrulline.
Billiar, Timothy R. +5 more
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HPW-Catalyzed environmentally benign approach to imidazo[1,2-a]pyridines
Beilstein Journal of Organic ChemistryThe imidazo[1,2-a]pyridine moiety is present in drugs with several biological activities. The most direct way of obtaining this nucleus is the Groebke–Blackburn–Bienaymé three-component reaction (GBB-3CR) between aminopyridines, aldehydes, and ...
Luan A. Martinho +1 more
doaj +1 more source
Hydrogen bonding and tautomeric equilibria in Schiff bases derived from 2-amino pyridines: electronic spectral evidence for substituent effects [PDF]
, 1986 Schiff bases of the type C6H3(R)(OH) CH = NC5H3N(Y)[where R = H, 3-OCH3, 5,6-benzo, 3-CHO-5-CH3,5-CI, 5-Br, 5-CH3, 4-CH3, 3-nitro and 5-nitro and Y=H, 3-CH3 4-CH3, 5-CH3, 6-CH3, 4,6-demethyl and 5-CI) have now been, synthesised and evidence sought for ...
Ramasami, T. +3 more
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Les 2-Aminopyridines: Synthèse, Complexation et Activités Biologiques [PDF]
, 2020 Le but de ce travail de mémoire de master est la synthèse et caractérisation de nouveaux ligands dérivés de la 2-aminopyridine ainsi que leurs complexes de métaux de transition.
Ferdjii, Zeyneb
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