Results 11 to 20 of about 4,204 (201)
Tautomerization, molecular structure, transition state structure, and vibrational spectra of 2-aminopyridines: a combined computational and experimental study. [PDF]
Al-Otaibi JS.
europepmc +2 more sources
A green synthetic protocol for cyclization of 2-aminopyridines with 2-bromoacetophenones to prepare imidazo[1,2-a]pyridines, followed by its successive iodination in one-pot manner, employing base-washed graphene oxide as the catalyst, in water has been ...
Sumit Das +4 more
doaj +1 more source
Synthesis of 3-aminoimidazo[1,2-a]pyridines via three-component reaction in the 2,2,2-trifluoroethanol-water two-phase systems [PDF]
An efficient synthesis of 3-aminoimidazo[1,2-a]pyridines via three-component reaction from aromatic aldehydes, 2-aminopyridines and isonitriles at room temperature in water/2,2,2-trifluoroethanol two-phase systems is described.
Mobina Alizade-Majd +2 more
doaj +1 more source
An operationally simple and metal-free approach is described for the synthesis of pyrazole-tethered thioamide and amide conjugates. The thioamides were generated by employing a three-component reaction of diverse pyrazole C-3/4/5 carbaldehydes, secondary
Shubham Sharma +8 more
doaj +1 more source
Entry point into new trimeric and tetrameric imide-based macrocyclic esters derived from isophthaloyl dichloride and methyl 6-aminonicotinate [PDF]
The one-step reaction of isophthaloyl dichloride with the 2-aminopyridine derivative (methyl 6-aminonicotinate) yields (i) a trimer-based macrocycle (EsIO)3 and (ii) a tetramer-based macrocycle (EsIO)4 in modest isolated synthetic yields (total of 25 ...
Gallagher, John F., Mocilac, Pavle
core +2 more sources
Imidazo[1,2-a]pyridines belong to a class of heterocyclic motifs possessing unique structural and pharmacological properties making them an interesting and promising domain in the fields of drug discovery and medicinal chemistry.
Mohan Neetha +2 more
doaj +1 more source
A simple and efficient protocol has been demonstrated for the preparation of densely functionalized 3-aroylimidazo[1,2-a]pyridines from 2-aminopyridines and chalcones using RuCl3·H2O/I2 catalytic system.
P.V. Sri Ramya +5 more
doaj +1 more source
Halogenation of pyridinium-N-(2'-pyridyl)aminide: an easy synthesis of halo-2-aminopyridines [PDF]
The regioselective halogenatmn of pyrldmium-N-(2’-pyridyljaminide 1 with N-chloro,\ud bromo or iodosuccinimtde under mild conditions IS described. The method, combined with a\ud reductmn of the N-N bond, allows an easy preparation of 5-h& and 3,5-dihalo ...
Burgos García, Carolina +4 more
core +2 more sources
Concise synthesis of rare pyrido[1,2-a]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen. [PDF]
Pyrido[1,2-a]pyrimidin-2-ones represent a pharmaceutically interesting class of heterocycles. The structurally related pyrido[1,2-a]pyrimidin-4-ones are associated with a broad range of useful biological properties.
Alanine, TA +5 more
core +1 more source
Novel pyridine-based fluorescing compounds, viz. pyrido[1,2-a]pyrrolo[3,4-d]pyrimidines 3a,b and N-methyl-4-((pyridin-2-yl)amino)maleimides 4a–e, were selectively prepared by a one-pot reaction between a functionalized maleimide and 2-aminopyridines with
Masayori Hagimori +4 more
doaj +1 more source

