Results 31 to 40 of about 4,204 (201)

Bis(2-aminopyridine)dibenzoatocobalt(II)

open access: yesActa Crystallographica Section E Structure Reports Online, 2006
The title compound, [Co(C7H5O2)2(C5H6N2)2], contains CoII cations bonded to two bidentate benzoate ligands and two 2-aminopyridine ligands, resulting in highly distorted cis-CoN2O4 octahedra. The crystal structure is stabilized by N—H...O hydrogen bonds.
Wen-Zheng Ju   +3 more
openaire   +1 more source

Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]

open access: yes, 2018
Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core   +2 more sources

Efficient Synthesis of 2-Aminopyridine Derivatives: Antibacterial Activity Assessment and Molecular Docking Studies

open access: yesMolecules, 2022
A new and suitable multicomponent one-pot reaction was developed for the synthesis of 2-amino-3-cyanopyridine derivatives. Background: This synthesis was demonstrated by the efficient and easy access to a variety of substituted 2-aminopyridines using ...
Zahira Kibou   +6 more
doaj   +1 more source

A structural systematic study of four isomers of difluoro-N-(3-pyridyl)benzamide [PDF]

open access: yes, 2009
The four isomers 2,4-, (I), 2,5-, (II), 3,4-, (III), and 3,5-difluoro-N-(3-pyridyl)benzamide, (IV), all with formula C12H8F2N2O, display molecular similarity, with interplanar angles between the C6/C5N rings ranging from 2.94 (11)° in (IV) to 4.48 (18 ...
Anderson, Frankie P.   +3 more
core   +1 more source

A New Class of Small Molecule Inhibitor of BMP Signaling [PDF]

open access: yes, 2013
Growth factor signaling pathways are tightly regulated by phosphorylation and include many important kinase targets of interest for drug discovery. Small molecule inhibitors of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1) are needed ...
Bullock, AN   +11 more
core   +7 more sources

An Improved Synthesis of 4-Chlorocoumarin-3-sulfonyl Chloride and Its Reactions with Different Bidentate Nucleophiles to Give Pyrido[1',2':2,3]- and Thiazino[3',2':2,3]-1,2,4-Thiadiazino[6,5-c]Benzopyran-6-one 7,7-Dioxides

open access: yesMolecules, 2007
An improved synthetic method affording 4-chlorocoumarin-3-sulfonyl chloride (4) in very good yield (ca. 85 %) is reported. This compound was reacted with various bidentate nucleophiles such as 2-aminopyridines and 2-aminothiazoles in order to obtain ...
Emil Popovski   +4 more
doaj   +1 more source

N-azinylpyridinium N-aminides: tandem reactions with alpha-halocarbonyl derivatives and analogs [PDF]

open access: yes, 2000
Pyridinium-N-(2´-pyridyl)aminide was reacted with different α-halocarbonyl derivatives and related compounds. The method allows an easy preparation of several heterocyclic building blocks, all including the 2-aminopyridine moietyAuthor wish to thank C.I ...
Burgos García, Carolina   +3 more
core   +2 more sources

SYNTHESIS AND PRECLINICAL STUDY OF ANTIOXIDANT ACTIVITY OF [1,2,4]TRIAZOLO[1,5-A]PYRIDINE DERIVATIVES

open access: yesBiota. Human. Technology, 2022
Purpose. Synthesis and study of antioxidant properties of [1,2,4]triazolo[1,5-a]pyridine derivatives and their potential toxicity using preclinical diagnostic methods. Methodology.
Олександр Смольський   +3 more
doaj   +1 more source

Recent advances in cyanamide chemistry: synthesis and applications [PDF]

open access: yes, 2017
The application of alkyl and aryl substituted cyanamides in synthetic chemistry has diversified multi-fold in recent years. In this review, we discuss recent advances (since 2012) in the chemistry of cyanamides and detail their application in ...
Crutchley   +7 more
core   +1 more source

One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction

open access: yesBeilstein Journal of Organic Chemistry, 2016
A novel three-component reaction has been developed to assemble biologically and pharmaceutically important tetracyclic fused imidazo[1,2-a]pyridines in a one-pot fashion utilizing readily available 2-aminopyridines, isatins and isocyanides.
Bo Yang   +4 more
doaj   +1 more source

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