Results 61 to 70 of about 1,355,229 (310)

A 2-Person Game Decomposing 2-Manifolds

open access: yes
Two players play a game by alternately splitting a surface of a compact $2$-manifold along a simple closed curve that is not null-homotopic and attaching disks to the resulting boundary; the last player who can move wins. Starting from an orientable surface, the $G$-series is $01\dot{2}\dot{0}$ according to increasing genus.
Berman, David R., Leonard, Lee O.
openaire   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

How to Play 3x3-Games A Strategy Method Experiment [PDF]

open access: yes
We report an experiment that uses the strategy method (Selten 1967) to elicit subjects' general strategy for playing any 2-person 3x3-game with integer payoffs between 0 and 99. Each two subjects' strategies play 500000 games in each of the 5 tournaments.
Abdolkarim Sadrieh   +3 more
core   +3 more sources

Collinearity between the Shapley value and the egalitarian division rules for cooperative games [PDF]

open access: yes, 1996
For each cooperativen-person gamev and eachh∈{1, 2, ⋯,n}, letv h be the average worth of coalitions of sizeh andv h i the average worth of coalitions of sizeh which do not contain playeri∈N. The paper introduces the notion of a proportional average worth
Dragan, Irinel   +2 more
core   +4 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Impact of Social Reward on the Evolution of the Cooperation Behavior in Complex Networks

open access: yesScientific Reports, 2017
Social reward, as a significant mechanism explaining the evolution of cooperation, has attracted great attention both theoretically and experimentally. In this paper, we study the evolution of cooperation by proposing a reward model in network population,
Yu’e Wu   +3 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Validation and comparison of virtual reality and 3D mobile games for cognitive assessment against ACE-III in 82 young participants

open access: yesScientific Reports
Current medical and clinical ecosystem for dementia detection is inadequate for its early detection. Traditional cognitive assessments are introduced after cognitive impairment has begun to disrupt the real-world functioning of the person.
Yesoda Bhargava   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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