Results 41 to 50 of about 6,535 (185)
Integrated microbiological, genomic, and structural analyses of bacteria isolated from a Peruvian geothermal system reveal enzymatic potential for the transformation of polyesters such as PET. This study links experimental evidence with genomic determinants and in silico analyses that support the thermophilic bacteria biodegradation capacity.
Marco A. Rivera‐Jacinto +6 more
wiley +1 more source
Glutamate toxicity has been implicated in neuronal cell death in both acute CNS injury and in chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, Fusarium solani ...
Hyun Gyu Choi +6 more
doaj +1 more source
Under gas-liquid microextraction (GLME) operating conditions (extraction temperature 270 °C, extraction time 7 min, condensation temperature −2 °C, and carrier nitrogen gas speed 2.5 mL/min), ice cream samples, as a representative food, were pre-treated.
Li Mu +6 more
doaj +1 more source
Three 2‐phosphinophenylaluminum dichloride complexes were synthesized and characterized as novel intramolecular FLPs. These FLP systems exhibit high Lewis acidity and effectively activate challenging substrates including aliphatic ketones, imines, and esters. DFT analysis revealed that strain release and Al–P dynamics govern their reactivity. Abstract (
Yoshihiro Nishimoto +2 more
wiley +1 more source
Main Ustilaginoidins and Their Distribution in Rice False Smut Balls
Rice false smut has become an increasingly serious fungal disease in rice (Oryza sativa L.) production worldwide. Ustilaginoidins are bis-naphtho-γ-pyrone mycotoxins previously isolated from the rice false smut balls (FSBs) infected by the pathogen ...
Jiajia Meng +9 more
doaj +1 more source
Dissection and Engineering of Modular Polyketide Synthase Extender Unit Specificity Motifs
Motif‐level engineering of acyltransferase domains in polyketide synthases enables programable extender unit selectivity. Cooperative mutations and motif exchanges reprogram substrate preference, enabling the incorporation of non‐native extender units and expanding polyketide structural diversity, with gains in activity and product yield.
Sydney Welch, Gavin J. Williams
wiley +1 more source
Penichrypyrone A: A New γ-Pyrone Derivative from the Sponge-Derived Fungus LS18
A new γ -pyrone derivative, penichrypyrone A ( 1 ), along with 4 known compounds, conichaetone E ( 2 ), janthinone ( 3 ), mrlactonel ( 4 ), and aspergillusene A ( 5 ), was isolated from the EtOAc extract of the sponge-derived fungus Penicillium ...
Xiaoping He +6 more
doaj +1 more source
The reaction of 4-hydroxycoumarin (1) with some primary amines 2a-h and morpholine (2i) under microwave irradiation occurred without opening of the lactone ring to give N-substituted 4-aminocoumarins 3a-i in excellent yields.
Ivo C. Ivanov, Edmont V. Stoyanov
doaj +1 more source
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi +6 more
wiley +1 more source
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam +3 more
wiley +1 more source

