Results 51 to 60 of about 17,659,431 (225)

Total Synthesis and Stereochemical Revision of Phacelocarpus 2‐Pyrone A

, 2015
The first total synthesis of phacelocarpus 2-pyrone A is reported. The original natural compound was tentatively assigned (by NMR spectroscopy) as containing two cis-alkenes and a trans-vinyl ether connected to a 2-pyrone ring motif.
Thomas O. Ronson, Jason M. Lynam, Lynam, Jason M., Ronson, Thomas O., Ian J. S. Fairlamb, Burns, Michael J., Voelkel, Martin H. H., Fairlamb, Ian J. S., Martin H. H. Voelkel, Richard J. K. Taylor, Michael J. Burns, Taylor, Richard J. K., Evans, Kieren J., Kieren J. Evans   +13 more
core   +1 more source

Alkyl Arylacetates in Cascade Reactions with 2‐Cyanobenzaldehydes for the Synthesis of 3‐Substituted Isoindolinones

European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
Effective synthesis of 3‐substituted isoindolinones is possible through novel cascade reactions of alkyl arylacetates with 2‐cyanobenzaldehydes under mild, basic conditions. Herein we report the use of alkyl arylacetates as pro‐nucleophiles in cascade reactions with 2‐cyanobenzaldehydes leading to the formation of novel 3‐substituted isoindolinones, a ...
Antonia Di Mola, Prabaharan Thiruvengetam, Alessandra Forlenza, Armin R. Ofial, Antonio Massa   +4 more
wiley   +1 more source

Towards the total synthesis of Phacelocarpus-2-pyrone A: Novel 2-pyrone chemistry [PDF]

, 2010
This thesis describes the progress made towards the synthesis of the natural product phacelocarpus-2-pyrone A and the development of novel synthetic methodology for the synthesis of functionalised 2-pyrones.
Burns, Michael John
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Structure determination of a 4-pyrone from the liverwort Plagiochila bifaria (Sw.) Lindenb. (Plagiochilaceae) [PDF]

, 2008
The centenary of the presentation in 1907 of the "polyketide" hypothesis by Collie, along with his use of a 4-pyrone as an example, is marked by reporting the discovery and isolation of 2-(3,4-dimethoxyphenethyl)-6-methyl-4-pyrone from <i> ...
Rycroft, D.S.
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Neuroprotective γ-Pyrones from Fusarium Solani JS-0169: Cell-Based Identification of Active Compounds and an Informatics Approach to Predict the Mechanism of Action

Biomolecules, 2020
Glutamate toxicity has been implicated in neuronal cell death in both acute CNS injury and in chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, Fusarium solani ...
Hyun Gyu Choi, Ji Hoon Song, Musun Park, Soonok Kim, Chang-Eop Kim, Ki Sung Kang, Sang Hee Shim   +6 more
doaj   +1 more source

Application of Gas-Liquid Microextraction (GLME)/GC-MS for Flavour and Fragrance in Ice Cream Detection and Composition Analysis

Molecules, 2023
Under gas-liquid microextraction (GLME) operating conditions (extraction temperature 270 °C, extraction time 7 min, condensation temperature −2 °C, and carrier nitrogen gas speed 2.5 mL/min), ice cream samples, as a representative food, were pre-treated.
Li Mu, Qi Tong, Yuhang Liu, Xianglong Meng, Peng He, Gang Li, Linyang Ye   +6 more
doaj   +1 more source

Main Ustilaginoidins and Their Distribution in Rice False Smut Balls

Toxins, 2015
Rice false smut has become an increasingly serious fungal disease in rice (Oryza sativa L.) production worldwide. Ustilaginoidins are bis-naphtho-γ-pyrone mycotoxins previously isolated from the rice false smut balls (FSBs) infected by the pathogen ...
Jiajia Meng, Weibo Sun, Ziling Mao, Dan Xu, Xiaohan Wang, Shiqiong Lu, Daowan Lai, Yang Liu, Ligang Zhou, Guozhen Zhang   +9 more
doaj   +1 more source

Synthesis, Characterization and X-Ray Crystal Structures of Oxidovanadium(V) Complexes Derived from N’-(2-Hydroxy-5-methylbenzylidene)-4-methylbenzohydrazide with Antibacterial Activity

Acta Chimica Slovenica, 2023
A dinuclear oxidovanadium(V) complex [V2O2L2(OMe)2] (1) was synthesized from N’-(2-hydroxy-5-methylbenzylidene)-4-methylbenzohydrazide (H2L) and VO(acac)2 in MeOH.
Xue-Rong Tan, Wei Li, Meng-Meng Duan, Zhonglu You   +3 more
doaj   +1 more source

Anthraquinones From Epicoccum sp., a Fungus Isolated From Gut of Dione juno That Feeds on Passifloras

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
An Epicoccum fungus was isolated from gut of larvae of the butterfly Dione juno juno that feeds intensively on leaves of Passifloras. This fungus produces hydroxyanthraquinones that moderately inhibits growth of some Bacillus that coexist with the fungus in the insect gut, suggesting that it is probably important for microbial embalance in gut flora ...
Jessica Teixeira Dias, Alef dos Santos, Mauricio Augusto P. M. S. Alves, Clovis Wesley Oliveira de Souza, Eduardo Jorge Pilau, Edson Rodrigues‐Filho   +5 more
wiley   +1 more source

Anti-leukemic effect of 2-pyrone derivatives via MAPK and PI3 kinase pathways

, 2012
Substituted 2-pyrones are important structural sub-units present in a number of natural products having broad range of biological activity. However, little is known about the anti-cancer effect of 2-pyrone derivatives including leukemia.
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core   +1 more source