Results 51 to 60 of about 8,136 (224)
Breaking Down Barriers: CorA Effectively Targets Staphylococcal Biofilms in Vitro and in Vivo
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Corallopyronin A (CorA), a natural alpha‐pyrone antibiotic, penetrates Staphylococcus aureus biofilms and inhibits RNA polymerase. This work demonstrates CorA's superior efficacy compared to rifampicin and dalbavancin in reducing viable loads in biofilms both in vitro and in vivo. Graphic created in https://BioRender.com.
Stefania De Benedetti +21 more
wiley +1 more source
Pollutants Biodegradation by Fungi [PDF]
, 2009 Revisión sobre los mecanismos de detoxificación de contaminantes por hongosOne of the major problems facing the industrialized world today is the contamination of soils, ground water, sediments, surfacewater and air with hazardous and toxic chemicals ...
Aleu Casatejada, Josefina +2 more
core +2 more sources
Harnessing Photoenzymatic Systems for Intermolecular C–H Fluorination
Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.Despite the remarkable versatility of enzymes for catalyzing complex organic transformations under mild aqueous conditions, no biocatalytic system has been reported for intermolecular C–H fluorination. A radical photoenzymatic approach is introduced that leverages a designed de novo protein scaffold with an unnatural amino acid to achieve precise ...
Yu Zhou +7 more
wiley +2 more sources
Photo-Cycloaddition Reactions of 2-Pyrones [PDF]
Bulletin of the Chemical Society of Japan, 1990 Abstract Sensitized photoreactions of two 2-pyrones with five unsaturated compounds were investigated. The reactions of 2-pyrones with electron-deficient ethylenes gave [4+2]cycloadducts (3) and [2+2]cycloadducts (4) across the C5–C6 double bonds in the 2-pyrones.
Kenichi Somekawa +3 more
openaire +1 more source
MedComm, Volume 7, Issue 4, April 2026.This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva +3 more
wiley +1 more source
Molecules, 2023 Under gas-liquid microextraction (GLME) operating conditions (extraction temperature 270 °C, extraction time 7 min, condensation temperature −2 °C, and carrier nitrogen gas speed 2.5 mL/min), ice cream samples, as a representative food, were pre-treated.
Li Mu +6 more
doaj +1 more source
Regioselective Synthesis of 3-Alkynyl-5-bromo-2-pyrones via Pd-Catalyzed Couplings on 3,5-Dibromo-2-pyrone [PDF]
Organic Letters, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Jin-Hee, Lee +2 more
openaire +2 more sources
Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells [PDF]
, 2013 Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium oleander has been used in traditional medicine for treating several disorders including cancer, and extracts from the leaves of this ...
Burgos Morón, Estefanía +4 more
core +2 more sources
Main Ustilaginoidins and Their Distribution in Rice False Smut Balls
Toxins, 2015 Rice false smut has become an increasingly serious fungal disease in rice (Oryza sativa L.) production worldwide. Ustilaginoidins are bis-naphtho-γ-pyrone mycotoxins previously isolated from the rice false smut balls (FSBs) infected by the pathogen ...
Jiajia Meng +9 more
doaj +1 more source