Results 31 to 40 of about 2,638 (179)

Activation of the Nuclear Factor E2-Related Factor 2 Pathway by Novel Natural Products Halomadurones A–D and a Synthetic Analogue

Marine Drugs, 2013
Two novel chlorinated pyrones, halomadurones A and B, and two novel brominated analogues, halomadurones C and D, were isolated from a marine Actinomadura sp. cultivated from the ascidian Ecteinascidia turbinata.
Thomas P. Wyche, Miranda Standiford, Yanpeng Hou, Doug Braun, Delinda A. Johnson, Jeffrey A. Johnson, Tim S. Bugni   +6 more
doaj   +1 more source

Two New Pyrone Derivatives from the Plant Endophytic Fungus sp

Natural Product Communications, 2014
Two new α-pyrones, Exserolide G–H (1–2) , together with one known metabolite, stemphypyrone (3) , were isolated from the solid-substrate fermentation cultures of the plant endophytic fungus Exserohilum sp.
Ruxin Li, Shubin Niu, Liangdong Guo, Yang Zhang   +3 more
doaj   +1 more source

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

Frontiers in Marine Science, 2022
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6), along with five known compounds eurothiocin A (4), nodulisporipyrone A (7 ...
Ruohan Zhang, Ruohan Zhang, Jinxin Zhang, Jinxin Zhang, Ruiyun Huo, Ruiyun Huo, Yaxin Xue, Kui Hong, Ling Liu, Ling Liu   +9 more
doaj   +1 more source

Whole-genome sequencing of Aspergillus tubingensis G131 and overview of its secondary metabolism potential

BMC Genomics, 2018
Background Black Aspergilli represent one of the most important fungal resources of primary and secondary metabolites for biotechnological industry.
Elodie Choque, Christophe Klopp, Sophie Valiere, José Raynal, Florence Mathieu   +4 more
doaj   +1 more source

Mesityl‐Substituted Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxalines: Synthesis, Functionalization, Photophysical, and Electrochemical Properties

European Journal of Organic Chemistry, EarlyView.
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi, Hiroki Mizuno, Ikumi Uchiyama, Souta Yuruka, Atsuya Shimizu, Taku Shoji, Shunji Ito   +6 more
wiley   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

The FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner, Douglas M. M. Soares, Bianca B. Nóbrega, Etelvino J. H. Bechara, Zinaida M. Kaskova, Alexander S. Mishin, Karen S. Sarkisyan, Ilia V. Yampolsky, Cassius V. Stevani   +8 more
wiley   +1 more source

Two New Bioactive α-Pyrones from Hypericum japonicum

Molecules, 2016
Hypericum japonicum (Guttiferae), a type of annual or perennial herb, has been historically applied to cure infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, and internal hemorrhage.
Linzhen Hu, Zhenzhen Wang, Jinwen Zhang, Yuanyuan Lu, Kaiping Wang, Yongbo Xue, Yu Zhang, Yonghui Zhang   +7 more
doaj   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Pyran Rings Containing Polyketides from Penicillium raistrickii

Marine Drugs, 2016
Five new pyran rings containing polyketides, penicipyrans A–E (1–5), together with the known pestapyrone A (6), were isolated from the saline soil-derived Penicillium raistrickii. Their structures were determined by interpretation of NMR and HRESIMS data.
Li-Ying Ma, De-Sheng Liu, De-Guo Li, Yu-Ling Huang, Hui-Hui Kang, Chun-Hua Wang, Wei-Zhong Liu   +6 more
doaj   +1 more source