Results 31 to 40 of about 2,659 (180)

Two New Pyrone Derivatives from the Plant Endophytic Fungus sp

open access: yesNatural Product Communications, 2014
Two new α-pyrones, Exserolide G–H (1–2) , together with one known metabolite, stemphypyrone (3) , were isolated from the solid-substrate fermentation cultures of the plant endophytic fungus Exserohilum sp.
Ruxin Li   +3 more
doaj   +1 more source

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

open access: yesFrontiers in Marine Science, 2022
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6), along with five known compounds eurothiocin A (4), nodulisporipyrone A (7 ...
Ruohan Zhang   +9 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John   +4 more
wiley   +1 more source

Whole-genome sequencing of Aspergillus tubingensis G131 and overview of its secondary metabolism potential

open access: yesBMC Genomics, 2018
Background Black Aspergilli represent one of the most important fungal resources of primary and secondary metabolites for biotechnological industry.
Elodie Choque   +4 more
doaj   +1 more source

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

open access: yesChemFoodChem, EarlyView.
Free phenolic hydroxyl groups in the chemical structure of the natural xanthone α‐mangostin (MGT) contribute positively to achieving the anticancer profile against murine colon cancer, murine triple negative breast cancer, and human osteosarcoma cancer. ABSTRACT The α‐mangostin (MGT) is a natural xanthone obtained from the pericarp of mangosteen fruit (
Otávio Augusto Chaves   +7 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman   +6 more
wiley   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

Isotelluroureas for Asymmetric C1 Ammonium Enolate Reactions

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 31, 19 August 2026.
Chiral isotelluroureas are powerful catalysts for a variety of C─C bond forming C1 ammonium enolate transformations. Isotelluroureas (ITeUs) have recently been introduced as a novel class of highly nucleophilic Lewis base catalysts. Herein, we systematically screened them for their potential to facilitate C1 ammonium enolate transformations and ...
Fereshteh Khorasani   +3 more
wiley   +1 more source

Pyran Rings Containing Polyketides from Penicillium raistrickii

open access: yesMarine Drugs, 2016
Five new pyran rings containing polyketides, penicipyrans A–E (1–5), together with the known pestapyrone A (6), were isolated from the saline soil-derived Penicillium raistrickii. Their structures were determined by interpretation of NMR and HRESIMS data.
Li-Ying Ma   +6 more
doaj   +1 more source

Reimagining Lignin Valorization: Synthetic Biology–Enabled Sustainable Aromatic Carbon Biomanufacturing

open access: yesAdvanced Science, Volume 13, Issue 47, 24 August 2026.
The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li   +4 more
wiley   +1 more source

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