Results 41 to 50 of about 2,638 (179)

Iron Complexes With Proteins, Carbohydrates, and Maillard Products in Dairy Systems: Implication for Fortification, Bioavailability, and Product Functionality

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT The global prevalence of iron (Fe) deficiency anemia (IDA) continues to pose major public health challenges, necessitating the development of effective fortification strategies. Dairy‐based systems are promising vehicles for Fe fortification and delivery due to their widespread consumption and nutritional value, although their complex matrix ...
Ishara De Silva, Mary Ann Augustin, Thom Huppertz, Julia YQ Low, Arianna Dick, Jayani Chandrapala   +5 more
wiley   +1 more source

Bioactive α-Pyrone Derivatives from the Endophytic Fungus Diaporthe sp. CB10100 as Inducible Nitric Oxide Synthase Inhibitors

Frontiers in Chemistry, 2021
Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and ...
Hong Pu, Hong Pu, Hong Pu, Jianxin Liu, Yeji Wang, Yuhui Peng, Wanying Zheng, Yang Tang, Boping Hui, Chunmei Nie, Xueshuang Huang, Yanwen Duan, Yanwen Duan, Yanwen Duan, Yong Huang, Yong Huang   +15 more
doaj   +1 more source

Coumarins Disrupt Cell–Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
The selective nature through which coumarin compounds produced by different species of plants target PQS signalling in Pseudomonas aeruginosa and select for distinct phenotypic responses in key pathogenic organisms adds to the growing evidence of their utility as natural virulence suppressors. ABSTRACT Cell‐to‐cell communication in microbial systems is
Dylan Boon, Benjamin O'Rourke, Muireann Carmody, David F. Woods, Antje Gloe, Daniel Platero‐Rochart, Pedro A. Sánchez‐Murcia, Gerard P. McGlacken, F. Jerry Reen   +8 more
wiley   +1 more source

Benzyl Furanones and Pyrones from the Marine-Derived Fungus Aspergillus terreus Induced by Chemical Epigenetic Modification

Molecules, 2020
Chemical epigenetic modification on a marine-derived fungus Aspergillus terreus RA2905 using a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), resulted in a significantly changed metabolic profile.
Jing-Shuai Wu, Xiao-Hui Shi, Ya-Hui Zhang, Chang-Lun Shao, Xiu-Mei Fu, Xin Li, Guang-Shan Yao, Chang-Yun Wang   +7 more
doaj   +1 more source

Secondary Metabolites Diversity of Aspergillus unguis and Their Bioactivities: A Potential Target to Be Explored

Biomolecules, 2022
Aspergillus unguis belongs to the Aspergillus section Nidulantes. This species is found in soils and organisms from marine environments, such as jellyfishes and sponges. The first chemical study reported in the literature dates from 1970, with depsidones
Levy Tenório Sousa Domingos, Raquel dos Santos Martins, Leonardo Melo de Lima, Angela Michelato Ghizelini, Antonio Ferreira-Pereira, Fernando Cotinguiba   +5 more
doaj   +1 more source

Alkyl Arylacetates in Cascade Reactions with 2‐Cyanobenzaldehydes for the Synthesis of 3‐Substituted Isoindolinones

European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
Effective synthesis of 3‐substituted isoindolinones is possible through novel cascade reactions of alkyl arylacetates with 2‐cyanobenzaldehydes under mild, basic conditions. Herein we report the use of alkyl arylacetates as pro‐nucleophiles in cascade reactions with 2‐cyanobenzaldehydes leading to the formation of novel 3‐substituted isoindolinones, a ...
Antonia Di Mola, Prabaharan Thiruvengetam, Alessandra Forlenza, Armin R. Ofial, Antonio Massa   +4 more
wiley   +1 more source

Bioactive Monoterpenes and Polyketides from the Ascidian-Derived Fungus Diaporthe sp. SYSU-MS4722

Marine Drugs, 2022
There has been a tremendous increase in the rate of new terpenoids from marine-derived fungi being discovered, while new monoterpenes were rarely isolated from marine-derived fungi in the past two decades. Three new monoterpenes, diaporterpenes A–C (1–3),
Guifa Zhai, Senhua Chen, Hongjie Shen, Heng Guo, Minghua Jiang, Lan Liu   +5 more
doaj   +1 more source

Anthraquinones From Epicoccum sp., a Fungus Isolated From Gut of Dione juno That Feeds on Passifloras

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
An Epicoccum fungus was isolated from gut of larvae of the butterfly Dione juno juno that feeds intensively on leaves of Passifloras. This fungus produces hydroxyanthraquinones that moderately inhibits growth of some Bacillus that coexist with the fungus in the insect gut, suggesting that it is probably important for microbial embalance in gut flora ...
Jessica Teixeira Dias, Alef dos Santos, Mauricio Augusto P. M. S. Alves, Clovis Wesley Oliveira de Souza, Eduardo Jorge Pilau, Edson Rodrigues‐Filho   +5 more
wiley   +1 more source

Engineering an Acyl‐CoA Ligase With Enhanced Activity Toward Synthetic CoA Alternatives

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
Engineering an acyl‐CoA ligase shifts thiol specificity toward inexpensive synthetic thiols such as N‐acetylcysteamine (SNAC), enabling enzymatic generation of acyl‐SNAC starter units that support polyketide biosynthesis. Fatty acyl‐coenzyme A (CoA) thioesters are indispensable intermediates in primary metabolism and essential building blocks for ...
Jared R. Cossin, Sarah A. Taboada, Gavin J. Williams   +2 more
wiley   +1 more source

A 3-Vinyl Cephem Derivative, a Useful Intermediate in the Synthesis of Cepham Antibiotics, from Associated with Banana Fruit

Natural Product Communications, 2015
Aspergillus awamori was isolated from a diseased banana fruit, Musa acuminata cv. Ambul. The fungus was fermented in potato dextrose broth and on potato dextrose agar media and the fungal media were extracted with EtOAc. Chromatographic separation of the
H.M.S.K.H Bandara, N. Savitri Kumar, Lalith Jayasinghe, Hironori Masubuti, Yoshinori Fujimoto   +4 more
doaj   +1 more source