Results 1 to 10 of about 6,479 (182)
Engineering Comamonas testosteroni for the production of 2-pyrone-4,6-dicarboxylic acid as a promising building block [PDF]
Microbial Cell Factories, 2023 Background Plastics are an indispensable part of our daily life. However, mismanagement at their end-of-life results in severe environmental consequences.
Tom Delmulle +6 more
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Recent Advances in the Synthesis of 2-Pyrones [PDF]
Marine Drugs, 2015 The present review summarizes the recent progresses in the synthesis of 2-pyrones and the application to the synthesis of marine natural products. Especially, much attention was placed on the transition metal catalyzed synthetic methodologies in this ...
Jong Seok Lee
doaj +3 more sources
Engineering an Acyl-CoA Ligase With Enhanced Activity Toward Synthetic CoA Alternatives. [PDF]
ChembiochemEngineering an acyl‐CoA ligase shifts thiol specificity toward inexpensive synthetic thiols such as N‐acetylcysteamine (SNAC), enabling enzymatic generation of acyl‐SNAC starter units that support polyketide biosynthesis. Fatty acyl‐coenzyme A (CoA) thioesters are indispensable intermediates in primary metabolism and essential building blocks for ...
Cossin JR, Taboada SA, Williams GJ.
europepmc +2 more sources
A Three-Step Route to Functionalized Pyrrole-2,5-Dicarboxylic Acids from Galactaric Acid. [PDF]
ChemSusChemGalactaric acid (GalA) has been used as substrate for a library of N‐substituted pyrrole‐2,5‐dicarboxylic acids (PDCAs). Existing routes to N‐substituted PDCAs require many steps or lack product isolation. We present a simple, scalable three‐step synthesis from GalA via a 2‐pyrone salt, giving isolated PDCA derivatives in high yield without ...
Trapasso G +3 more
europepmc +2 more sources
4-Hydroxy-2-pyrones: Synthesis, Natural Products, and Application
Organics, 2023 4-Hydroxy-2-pyrones are of interest as potential biorenewable molecules for a sustainable transition from biomass feedstock to valuable chemical products.
Vladislav V. Fedin +3 more
doaj +1 more source
A facile synthesis in aqueous medium of 3-hydroxy-2-pyrone from aldaric acids or their derivatives
Results in Chemistry, 2022 3-Hydroxy-2-pyrone is a valuable building block of many molecules. The syntheses until now proposed to prepare this compound are not ecofriendly and are unsuitable for large scale productions.
Gabriella Leonardi +3 more
doaj +1 more source
Two new -Methoxy--Pyrones From the Mangrove Sediment-Derived SCSIO NS126
Natural Product Communications, 2021 Two new α -methoxy- γ -pyrone analogs, 2-methoxy-3-methyl-5,6-diethyl- γ -pyrone ( 2 ) and 2-methoxy-3,5-dimethyl-6-propyl- γ -pyrone ( 3 ), together with 2-methoxy-3,5-dimethyl-6-ethyl- γ -pyrone ( 1 ), firstly isolated from natural sources, were ...
Kunlong Li +6 more
doaj +1 more source
Antibiotics, 2022 Urinary tract infection (UTI) is one of the most common bacterial infections in the world, which is associated with high morbidity and mortality rates.
Ahmed M. E. Kotb +5 more
doaj +1 more source
Results in Chemistry, 2021 A cascade Diels-Alder reaction coupled with an oxidative aromatization reaction was developed and applied to a chiral 2-pyrone for the synthesis of the relevant chiral synthon/chiral auxiliary (-)-cis-aminoindan-2-ol.
Arturo de la Rosa-Barrales +6 more
doaj +1 more source
Divergent Asymmetric Total Synthesis of All Four Pestalotin Diastereomers from (R)-Glycidol
Molecules, 2020 All four chiral pestalotin diastereomers were synthesized in a straightforward and divergent manner from common (R)-glycidol. Catalytic asymmetric Mukaiyama aldol reactions of readily-available bis(TMSO)diene (Chan’s diene) with (S)-2 ...
Mizuki Moriyama +3 more
doaj +1 more source