Biosynthesis of α-pyrones [PDF]
The α-pyrone moiety is a structural feature found in a huge variety of biologically active metabolites. In recent times new insights into additional biosynthetic mechanisms, yielding in such six-membered unsaturated ester ring residues have been obtained.
Till F Schäberle
exaly +5 more sources
Atom-Economic Synthesis of 4-Pyrones from Diynones and Water
Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to ...
Yan-Li Xu, Teng Qinghu, Heng-Shan Wang
exaly +4 more sources
Nocapyrones: α- and γ-Pyrones from a Marine-Derived Nocardiopsis sp. [PDF]
One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2–4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment.
Youngju Kim +7 more
doaj +3 more sources
An Overview of α-Pyrones as Phytotoxins Produced by Plant Pathogen Fungi [PDF]
Crop diseases negatively affect the quality and quantity of agricultural products, with significant economic and social consequences. These problems become emergencies in a world where the safe production of food for human health is becoming increasingly
Antonio Evidente
doaj +2 more sources
2-(2-(Dimethylamino)vinyl)-4H-pyran-4-ones as Novel and Convenient Building-Blocks for the Synthesis of Conjugated 4-Pyrone Derivatives [PDF]
A straightforward approach for the construction of the new class of conjugated pyrans based on enamination of 2-methyl-4-pyrones with DMF-DMA was developed.
Dmitrii L. Obydennov +8 more
doaj +2 more sources
Phytochemical Profiling, Antioxidant and Cognitive-Enhancing Effect of Helichrysum italicum ssp. italicum (Roth) G. Don (Asteraceae) [PDF]
This study aimed at the evaluation of the antioxidant and cognitive-enhancing effect of methanol–aqueous extract from Helichrysum italicum ssp. italicum aerial parts.
Reneta Gevrenova +6 more
doaj +2 more sources
Natural Dibenzo-α-Pyrones and Their Bioactivities
Natural dibenzo-α-pyrones are an important group of metabolites derived from fungi, mycobionts, plants and animal feces. They exhibit a variety of biological activities such as toxicity on human and animals, phytotoxicity as well as cytotoxic ...
Daowan Lai, Ligang Zhou
exaly +3 more sources
Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities
Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating ...
Ali Wang, Daowan Lai, Ligang Zhou
exaly +3 more sources
Goondapyrones A–J: Polyketide α and γ Pyrone Anthelmintics from an Australian Soil-Derived Streptomyces sp. [PDF]
An investigation of ×19 soil samples collected under the auspices of the Australian citizen science initiative, Soils for Science, returned ×559 chemically dereplicated microbial isolates, of which ×54 exhibited noteworthy anthelmintic activity against ...
Shengbin Jin +7 more
doaj +2 more sources
Eight new α-pyrone and γ-butenolide derivatives from the plant endophytic fungus Diaporthe sp. CCY4 [PDF]
Five new α-pyrones, diaporpyrones G-K (1–5) and three new γ-butenolide derivatives, porbutenolides A-C (6–8), along with seven known compounds (9–15), were isolated from the culture extract of the endophytic fungus Diaporthe sp. CCY4.
Jie-Chun Zeng +4 more
doaj +2 more sources

