Results 21 to 30 of about 2,744 (177)

One-Pot Assembly of 2‑Pyrones through Copper-Catalyzed Cyclization of Propargylamines with Malonates [PDF]

Precision Chemistry
Junwei Li, Shuangshuang Liu, Liliang Huang, Junhai Huang, Huangdi Feng   +4 more
doaj   +2 more sources

Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes

Nature Communications, 2021
α-Pyridones and α-pyrones are ubiquitous structural motifs found in natural products and components of biologically active small molecules. Here, the authors report an oxidant-free Rh-catalyzed electrochemical divergent vinylic C–H annulation of ...
Yi-Kang Xing, Xin-Ran Chen, Qi-Liang Yang, Shuo-Qing Zhang, Hai-Ming Guo, Xin Hong, Tian-Sheng Mei   +6 more
doaj   +1 more source

CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum

Frontiers in Microbiology, 2021
Penicillium polonicum, commonly found on food matrices, is a mycotoxigenic species able to produce a neurotoxin called verrucosidin. This methylated α-pyrone polyketide inhibits oxidative phosphorylation in mitochondria and thereby causes neurological ...
Silvia Valente, Silvia Valente, Edoardo Piombo, Edoardo Piombo, Volker Schroeckh, Giovanna Roberta Meloni, Giovanna Roberta Meloni, Thorsten Heinekamp, Axel A. Brakhage, Axel A. Brakhage, Davide Spadaro, Davide Spadaro   +11 more
doaj   +1 more source

CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones

Journal of Fungi, 2023
Fusarium graminearum is a causal organism of Fusarium head blight in cereals and maize. Although a few secondary metabolites produced by F. graminearum are considered disease virulence factors, many molecular products of biosynthetic gene clusters ...
Carmen Hicks, Thomas E. Witte, Amanda Sproule, Anne Hermans, Samuel W. Shields, Ronan Colquhoun, Chris Blackman, Christopher N. Boddy, Rajagopal Subramaniam, David P. Overy   +9 more
doaj   +1 more source

Pd/C-Catalyzed Intramolecular C–H Arylation for the Synthesis of Phenanthridinones and Dibenzo-α-pyrones

SynOpen, 2017
Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly
Lingyu Zhao, Guodong Shen, Tongxin Zhang, Zhen Wang, Yuhua Liang   +4 more
doaj   +1 more source

One-pot synthesis of salicylaldehyde containing biaryl frameworks via an aminocatalytic Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones

Green Synthesis and Catalysis, 2020
Salicylaldehyde containing biaryls are efficiently synthesized via an unprecedented amine promoted Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones in good yields.
Xixi Song, Yueteng Zhang, Peng Ji, Fanxun Zeng, Fangchao Bi, Wei Wang   +5 more
doaj   +1 more source

New Naphtho-γ-Pyrones Isolated from Marine-Derived Fungus Penicillium sp. HK1-22 and Their Antimicrobial Activities

Marine Drugs, 2019
Three novel monomeric naphtho-γ-pyrones, peninaphones A−C (compounds 1−3), along with two known bis-naphtho-γ-pyrones (compounds 4 and 5) were isolated from mangrove rhizosphere soil-derived fungus Penicillium sp. HK1-22.
Yao-Yao Zheng, Zhao-Yang Liang, Nan-Xing Shen, Wen-Long Liu, Xiao-Jian Zhou, Xiu-Mei Fu, Min Chen, Chang-Yun Wang   +7 more
doaj   +1 more source

Emission solvatochromic, solid-state and aggregation-induced emissive α-pyrones and emission-tuneable 1H-pyridines by Michael addition–cyclocondensation sequences

Beilstein Journal of Organic Chemistry, 2019
Starting from substituted alkynones, α-pyrones and/or 1H-pyridines were generated in a Michael addition–cyclocondensation with ethyl cyanoacetate. The peculiar product formation depends on the reaction conditions as well as on the electronic substitution
Natascha Breuer, Irina Gruber, Christoph Janiak, Thomas J. J. Müller   +3 more
doaj   +1 more source

Nocapyrones: α- and γ-Pyrones from a Marine-Derived Nocardiopsis sp.

Marine Drugs, 2014
One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2–4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment.
Youngju Kim, Hiromu Ogura, Kazuaki Akasaka, Tsutomu Oikawa, Nobuyasu Matsuura, Chiaki Imada, Hisato Yasuda, Yasuhiro Igarashi   +7 more
doaj   +1 more source

Transition-metal-free [3+3] annulation reaction of sulfoxonium ylides with cyclopropenones for the synthesis of 2-pyrones

Green Synthesis and Catalysis, 2020
An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions.
Maoyao He, Yuncan Chen, Yi Luo, Jianglian Li, Ruizhi Lai, Zengbao Yang, Yuerong Wang, Yong Wu   +7 more
doaj   +1 more source