Synthesis of cyercenes and yangonin by a pyrone aldol protocol
Results in Chemistry, 2021 A number of 6-alkenyl pyrones were synthesized using an aldol reaction followed by a tosylate elimination sequence.
Kyle Podolak, George A. Kraus
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Isothiourea-mediated one-pot synthesis of trifluoromethyl substituted 2-pyrones [PDF]
, 2014 The authors thank the Royal Society for a University Research Fellowship (ADS) and the EPSRC (EP/J018139/1, DSBD) for funding.A one-pot isothiourea-mediated Michael addition/lactonization/thiol elimination cascade sequence for the formation of 4,6 ...
Smith, Andrew D. +9 more
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Two New Bioactive α-Pyrones from Hypericum japonicum
Molecules, 2016 Hypericum japonicum (Guttiferae), a type of annual or perennial herb, has been historically applied to cure infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, and internal hemorrhage.
Linzhen Hu +7 more
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استخراج و خالص سازی ماده موثره دارویی γ-Pyrones (خلین و ویسناژین) از گیاه Ammi Visnaga L. [PDF]
زیستشناسی کاربردی, 2023 گیاه Ammi Visnaga Lam. (تیره جعفری)، از جمله گیاهان دارویی ارزشمند بومی کشور می باشد که حاوی ماده موثرهدارویی γ-Pyrones (عمدتا محتوی خلین و ویسناژین) است.
محمد حاجی ابوالحسنی
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A convenient synthesis of substituted [gamma]-pyrones [PDF]
, 1980 An efficient and general synthetic method for various 2-mono- and 2,6-disubstituted [gamma]-pyrones has been developed. This utilizes the -acylation (70-85%) of [beta]-methoxy-[alpha],[beta]-enone lithium enolates by acid chlorides followed by the acid-
Hiroshi Akagi +3 more
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Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii [PDF]
, 2022 Diterpenoid pyrones are a type of mainly fungal meroterpenoid metabolite consisting of a diterpene connected to a pyrone, some of which show potent bioactivity.
Yohei Morishita +9 more
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Coumarins, Xanthones and Related Compounds
Molecules, 2016 It has long been known that coumarins (γ-pyrones) and xanthones (α-pyrones) together form a large class of naturally occurring compounds exhibiting a wide range of biological activities.[...]
Pascal Richomme
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Indenopyrans – synthesis and photoluminescence properties
Beilstein Journal of Organic Chemistry, 2016 New indeno[1,2-c]pyran-3-ones bearing different substituents at the pyran moiety were synthesized and their photophysical properties were investigated. In solution all compounds were found to be blue emitters and the trans isomers exhibited significantly
Andreea Petronela Diac +6 more
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Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes
Nature Communications, 2021 α-Pyridones and α-pyrones are ubiquitous structural motifs found in natural products and components of biologically active small molecules. Here, the authors report an oxidant-free Rh-catalyzed electrochemical divergent vinylic C–H annulation of ...
Yi-Kang Xing +6 more
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CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum
Frontiers in Microbiology, 2021 Penicillium polonicum, commonly found on food matrices, is a mycotoxigenic species able to produce a neurotoxin called verrucosidin. This methylated α-pyrone polyketide inhibits oxidative phosphorylation in mitochondria and thereby causes neurological ...
Silvia Valente +11 more
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