Results 41 to 50 of about 4,197 (216)

Transition-metal-free [3+3] annulation reaction of sulfoxonium ylides with cyclopropenones for the synthesis of 2-pyrones

open access: yesGreen Synthesis and Catalysis, 2020
An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions.
Maoyao He   +7 more
doaj   +1 more source

A novel route to 6-substituted and 5,6-disubstituted 2-pyrones [PDF]

open access: yes, 2001
6-Alkyl- and 6-(1-alkenyl)-5-iodo-2-pyrones, which are available as major products by reaction of the corresponding (Z)-2-en-4-ynoic acids with iodine and NaHCO3 in CH3CN, undergo insertion of activated zinc metal into their carbon-iodine bond to provide
ROSSI, RENZO   +3 more
core   +1 more source

Supercritical fluid extraction of γ-Pyrones from Ammi visnaga L. fruits

open access: yesFuture Journal of Pharmaceutical Sciences, 2018
Extraction with supercritical fluid technique has proved to be effective in many applications including extraction and separation of various active principals from medicinal plants.
Mokhtar Bishr   +4 more
doaj   +1 more source

Antimalarial 5,6-Dihydro-α-pyrones from Cryptocarya rigidifolia: Related Bicyclic Tetrahydro-α-Pyrones Are Artifacts [PDF]

open access: yes, 2015
Antimalarial bioassay-guided fractionation of an EtOH extract of the root wood of Cryptocarya rigidifolia (Lauraceae) led to the isolation of the five new 5,6-dihydro-α-pyrones cryptorigidifoliols A–E (1–5) and the six bicyclic tetrahydro-α-pyrone ...
L. Harinantenaina Rakotondraibe (1319352)   +9 more
core   +1 more source

Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2019
Due to the widespread occurrence and spread of anthelmintic resistance, there is a need to develop new drugs against resistant parasitic nematodes of livestock animals.
H.M.P. Dilrukshi Herath   +12 more
doaj   +1 more source

Mesityl‐Substituted Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxalines: Synthesis, Functionalization, Photophysical, and Electrochemical Properties

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi   +6 more
wiley   +1 more source

Mechanistic Analysis of 5-Hydroxy -Pyrones as Michael Acceptor Prodrugs [PDF]

open access: yes
Substituted 5-hydroxy γ-pyrones have shown promise as covalent inhibitor leads against cysteine proteases and tran- scription factors, but their hydrolytic instability has hindered optimization efforts.
Clifford, Leung   +4 more
core   +1 more source

Diels–Alder reactions of heterocyclic fused [alpha]-pyrones [PDF]

open access: yes, 1991
The chemistry of heterocyclic analogues of orthoquinodimethane is reviewed. Benzothieno[2,3-c]pyran-3-ones and the isomeric [3,2-c]pyranones are stable analogues of benzothiophene-2,3-qyinodimethane.
P. Mark Jackson (7165337)
core   +2 more sources

Bioactivity-Guided Screening of Antimicrobial Secondary Metabolites from Antarctic Cultivable Fungus Acrostalagmus luteoalbus CH-6 Combined with Molecular Networking

open access: yesMarine Drugs, 2022
With the increasingly serious antimicrobial resistance, discovering novel antibiotics has grown impendency. The Antarctic abundant microbial resources, especially fungi, can produce unique bioactive compounds for adapting to the hostile environment.
Ting Shi   +6 more
doaj   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

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