Results 41 to 50 of about 2,744 (177)
Molecules, 2019 An ultra-high-performance liquid chromatographic (UHPLC) separation was developed for six kava pyrones (methysticin, dihydromethysticin (DHM), kavain, dihydrokavain (DHK), desmethoxyyangonin (DMY), and yangonin), two unidentified components, and three ...
Yijin Tang, Christine Fields
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Ethnopharmacological Evaluation of a Wild Ecotype of Syzygium cumini (L.) Skeels (Jamoya) Fruit
Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.The phytochemical and biological activity of Syzygium cumini (ecotype) fruit pulp and seed extracts using GC‐MS, UHPLC‐QTOF‐MS, and antidiabetic potential. ABSTRACT The wild ecotype of Jamun (Syzygium cumini) is known for its inedible fruits that are not yet explored for their bioactive potential. The present study assesses the ethnopharmacological and
Ritu Sharma +4 more
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PLoS ONE, 2021 Aspergillus niger metabolites exhibited a wide range of biological properties including antioxidant and neuro-protective effects and some physical properties as green synthesis of silver nanoparticles AgNP. The present study presents a novel evidence for
Ghada Mahmoud Abdelwahab +5 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković +6 more
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Two Pyrones with Antibacterial Activities from
Natural Product Communications, 2016 A new pyrone derivative, malakavalactone ( 2 ), was isolated from the acetone extract of Alpinia malaccensis fruits, along with a known compound kavalactone ( 1 ).
Tita Juwitaningsih +2 more
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MicrobiologyOpen, Volume 15, Issue 4, August 2026.Integrated microbiological, genomic, and structural analyses of bacteria isolated from a Peruvian geothermal system reveal enzymatic potential for the transformation of polyesters such as PET. This study links experimental evidence with genomic determinants and in silico analyses that support the thermophilic bacteria biodegradation capacity.
Marco A. Rivera‐Jacinto +6 more
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Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.Three 2‐phosphinophenylaluminum dichloride complexes were synthesized and characterized as novel intramolecular FLPs. These FLP systems exhibit high Lewis acidity and effectively activate challenging substrates including aliphatic ketones, imines, and esters. DFT analysis revealed that strain release and Al–P dynamics govern their reactivity. Abstract (
Yoshihiro Nishimoto +2 more
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Dissection and Engineering of Modular Polyketide Synthase Extender Unit Specificity Motifs
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Motif‐level engineering of acyltransferase domains in polyketide synthases enables programable extender unit selectivity. Cooperative mutations and motif exchanges reprogram substrate preference, enabling the incorporation of non‐native extender units and expanding polyketide structural diversity, with gains in activity and product yield.
Sydney Welch, Gavin J. Williams
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European Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.Azuleno[1′,2′:4,5]pyrrolo[2,3‐b]quinoxaline with a mesityl group as a solubilizing group was synthesized. By synthesizing derivatives in which various functional groups were introduced into two electronically distinct sites, the pyrrole nitrogen atom and the azulene five‐membered ring, we were able to reveal that the photophysical and electrochemical ...
Ryuta Sekiguchi +6 more
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