Results 41 to 50 of about 14,691 (260)

CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones

open access: yesJournal of Fungi, 2023
Fusarium graminearum is a causal organism of Fusarium head blight in cereals and maize. Although a few secondary metabolites produced by F. graminearum are considered disease virulence factors, many molecular products of biosynthetic gene clusters ...
Carmen Hicks   +9 more
doaj   +1 more source

Nocapyrones A−D, γ-Pyrones from aNocardiopsisStrain Isolated from the Marine SpongeHalichondria panicea [PDF]

open access: yes, 2010
Four new γ-pyrones, nocapyrones A−D (1−4), were isolated from an organic extract of the Nocardiopsis strain HB383, which was isolated from the marine sponge Halichondria panicea. These are the first γ-pyrones reported from a Nocardiopsis strain.
Imhoff, Johannes F.   +5 more
core   +1 more source

From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]

open access: yes, 2011
In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F   +3 more
core   +2 more sources

Pd/C-Catalyzed Intramolecular C–H Arylation for the Synthesis of Phenanthridinones and Dibenzo-α-pyrones

open access: yesSynOpen, 2017
Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly
Lingyu Zhao   +4 more
doaj   +1 more source

One-pot synthesis of salicylaldehyde containing biaryl frameworks via an aminocatalytic Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones

open access: yesGreen Synthesis and Catalysis, 2020
Salicylaldehyde containing biaryls are efficiently synthesized via an unprecedented amine promoted Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones in good yields.
Xixi Song   +5 more
doaj   +1 more source

Functional characterization and expression of GASCL1 and GASCL2, two anther-specific chalcone synthase like enzymes from Gerbera hybrida [PDF]

open access: yes, 2017
The chalcone synthase superfamily consists of type III polyketidesynthases (PKSs), enzymes responsible for producing plant secondary metabolites with various biological and pharmacological activities. Anther-specific chalcone synthase-like enzymes (ASCLs)
Albert, Victor A.   +5 more
core   +1 more source

Emission solvatochromic, solid-state and aggregation-induced emissive α-pyrones and emission-tuneable 1H-pyridines by Michael addition–cyclocondensation sequences

open access: yesBeilstein Journal of Organic Chemistry, 2019
Starting from substituted alkynones, α-pyrones and/or 1H-pyridines were generated in a Michael addition–cyclocondensation with ethyl cyanoacetate. The peculiar product formation depends on the reaction conditions as well as on the electronic substitution
Natascha Breuer   +3 more
doaj   +1 more source

Transition-metal-free [3+3] annulation reaction of sulfoxonium ylides with cyclopropenones for the synthesis of 2-pyrones

open access: yesGreen Synthesis and Catalysis, 2020
An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions.
Maoyao He   +7 more
doaj   +1 more source

Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid [PDF]

open access: yes, 2017
Dehydroacetic acid is a common pyrone derivative used commercially as an antibacterial and antifungal agent. Based on the synthesis of dehydroacetic acid (1) from N-hydroxysuccinimdyl acetoacetate, a novel series of enamine-based derivatives were ...
Baldwin, Alex   +4 more
core   +2 more sources

Supercritical fluid extraction of γ-Pyrones from Ammi visnaga L. fruits

open access: yesFuture Journal of Pharmaceutical Sciences, 2018
Extraction with supercritical fluid technique has proved to be effective in many applications including extraction and separation of various active principals from medicinal plants.
Mokhtar Bishr   +4 more
doaj   +1 more source

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