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Fusarium graminearum is a causal organism of Fusarium head blight in cereals and maize. Although a few secondary metabolites produced by F. graminearum are considered disease virulence factors, many molecular products of biosynthetic gene clusters ...
Carmen Hicks +9 more
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Nocapyrones A−D, γ-Pyrones from aNocardiopsisStrain Isolated from the Marine SpongeHalichondria panicea [PDF]
Four new γ-pyrones, nocapyrones A−D (1−4), were isolated from an organic extract of the Nocardiopsis strain HB383, which was isolated from the marine sponge Halichondria panicea. These are the first γ-pyrones reported from a Nocardiopsis strain.
Imhoff, Johannes F. +5 more
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From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]
In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F +3 more
core +2 more sources
Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly
Lingyu Zhao +4 more
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Salicylaldehyde containing biaryls are efficiently synthesized via an unprecedented amine promoted Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones in good yields.
Xixi Song +5 more
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Functional characterization and expression of GASCL1 and GASCL2, two anther-specific chalcone synthase like enzymes from Gerbera hybrida [PDF]
The chalcone synthase superfamily consists of type III polyketidesynthases (PKSs), enzymes responsible for producing plant secondary metabolites with various biological and pharmacological activities. Anther-specific chalcone synthase-like enzymes (ASCLs)
Albert, Victor A. +5 more
core +1 more source
Starting from substituted alkynones, α-pyrones and/or 1H-pyridines were generated in a Michael addition–cyclocondensation with ethyl cyanoacetate. The peculiar product formation depends on the reaction conditions as well as on the electronic substitution
Natascha Breuer +3 more
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An efficient and practical synthetic approach was developed for the tandem synthesis of trisubstituted 2-pyrone derivatives from sulfoxonium ylides and cyclopropenones. This [3+3] annulation reaction was carried out under transition-metal-free conditions.
Maoyao He +7 more
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Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid [PDF]
Dehydroacetic acid is a common pyrone derivative used commercially as an antibacterial and antifungal agent. Based on the synthesis of dehydroacetic acid (1) from N-hydroxysuccinimdyl acetoacetate, a novel series of enamine-based derivatives were ...
Baldwin, Alex +4 more
core +2 more sources
Supercritical fluid extraction of γ-Pyrones from Ammi visnaga L. fruits
Extraction with supercritical fluid technique has proved to be effective in many applications including extraction and separation of various active principals from medicinal plants.
Mokhtar Bishr +4 more
doaj +1 more source

