Downregulation of CYP17A1 by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties [PDF]
Aim: To investigate the effect of 20-hydroxyecdysone on steroidogenic pathway genes and plasma progesterone, and its potential impact on vascular functions.
Maneera Y Aljaber +11 more
doaj +4 more sources
Chemical Treatments for Insect Cell Differentiation: The Effects of 20-Hydroxyecdysone and Veratridine on Cultured Spodoptera frugiperda (Sf21) Insect Cell Ultrastructure [PDF]
Previous studies have shown that insect cell cultures stop dividing, form clumps, and can be induced to grow processes reminiscent of axons, when the culture medium is supplemented with 20-hydroxyecdysone, insulin, or an agent that mimics their action ...
Lacey J. Jenson +2 more
doaj +3 more sources
20-Hydroxyecdysone-responsive microRNAs of insects [PDF]
20-Hydroxyecdysone (20-HE) plays essential roles in coordinating developmental transitions of insects through responsive protein-coding genes and microRNAs (miRNAs). The involvement of single miRNAs in the ecdysone-signalling pathways has been extensively explored, but the interplay between ecdysone and the majority of miRNAs still remains largely ...
Xiaoli Jin, Shiping Liu
exaly +5 more sources
20-hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner [PDF]
Background: 20-hydroxyecdysone is an ecdysteroid which is abundant in plants and insects and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen ER-β receptor, which could potentially make it vasodilatory.
Nelson N Orie +9 more
doaj +2 more sources
Effects of dietary 20-hydroxyecdysone supplementation on whole-body protein turnover in growing pigs [PDF]
One of the approaches to creating biologically active additives for use in pig breeding can be the use of 20-hydroxyecdysone regulating protein metabolism in piglets.
Obvintseva Olga +2 more
doaj +2 more sources
A Phase 1 study for safety and pharmacokinetics of BIO101 (20‐hydroxyecdysone) in healthy young and older adults [PDF]
Background Sarcopenia is an age‐related skeletal muscle disorder characterized by loss of muscle mass and strength leading to mobility disability. 20‐Hydroxyecdysone (20E) is a polyhydroxylated plant steroid that demonstrates pharmacological effects in ...
Waly Dioh +8 more
doaj +2 more sources
Screening some of plants from Silene Genus for 20-Hydroxyecdysone
Eight Silene species include S. brachuica, S. guntensis, S. linicola, S. oreina, S. praemixta, S. pseudotites, S. viridiflora and S. wallichiana were screened for the main ecdysteroid 20-hydroxyecdysone by HPLC using the UV spectroscopy.
Nazim A. Mamedov +3 more
doaj +2 more sources
Molecular Targets of 20-Hydroxyecdysone in Mammals, Mechanism of Action: Is It a Calorie Restriction Mimetic and Anti-Aging Compound? [PDF]
The 20-hydroxyecdysone (20E) has been used in traditional medicine for a long time and acquired attention in the last decade as a food supplement and stimulant in physical activities.
Ernő Zádor
doaj +2 more sources
20-Hydroxyecdysone and Receptor Interplay in the Regulation of Hemolymph Glucose Level in Honeybee (Apis mellifera) Larvae [PDF]
The hormone 20-hydroxyecdysone (20E) and the ecdysone receptors (ECR and USP) play critical roles in the growth and metabolism of insects, including honeybees.
Jing Yu +6 more
doaj +2 more sources
One of the first tasks of worker honey bees (Apis mellifera) during their lifetime is to feed the larval offspring. In brief, young workers (nurse bees) secrete a special food jelly that contains a large amount of unique major royal jelly proteins (MRJPs)
Paul Winkler, Frank Sieg, Anja Buttstedt
doaj +2 more sources

