The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. [PDF]
, 2015 Schistosomiasis affects millions of people in developing countries and is responsible for more than 200,000 deaths annually. Because of toxicity and limited spectrum of activity of alternatives, there is effectively only one drug, praziquantel, available
Barnard, Andrew H +6 more
core +3 more sources
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.ABSTRACT Background Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of survival of motor neuron (SMN) protein inducing progressive muscle weakness and atrophy due to motor neurons degeneration. Despite benefits of SMN restoration therapies in patients, motor defects are still persistent.
Cynthia Bézier +13 more
wiley +1 more source
Stress in dipteran insects mass‐reared for sterile insect technique applications
Insect Science, Volume 32, Issue 5, Page 1495-1523, October 2025.The connections between biotic and abiotic stress affecting mass‐reared dipteran insects and the associated stress and immunological responses. Numbers indicate the order in which the topics are discussed in this review. Abstract Stress may be viewed as the disturbance of homeostasis of an organism.
Caroline K. Mirieri +3 more
wiley +1 more source
Phytoecdysteroids in the Genus (Polypodiaceae) of French Polynesia
Natural Product Communications, 2007 A chemical survey of the six species of Microsorum in French Polynesia has been performed to determine and quantify the phytoecdysteroids. The content and composition of these compounds in the fronds of each of the six species were established.
Raimana Ho +6 more
doaj +1 more source
In vitro cultures of pupal integumental explants to bioassay insect growth regulators with ecdysteroid activity for ecdysteroid amounts and cuticle secretion [PDF]
, 2007 The present study evaluated the in vitro bioassay with pupal integumental explants of the mealworm Tenebrio molitor to test the activity of two types of insect growth regulators (IGRs) with ecdysteroidal action. We assessed the imidazole derivative KK-42,
Berghiche, H +3 more
core +1 more source
Genomic Analysis of Drosophila Neuronal Remodeling: A Role for the RNA-Binding Protein Boule as a Negative Regulator of Axon Pruning [PDF]
, 2008 Drosophila mushroom body (MB) {gamma} neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches.
Hoopfer, Eric D. +3 more
core +1 more source
Scrambled Eggs: Apoptotic cell clearance by non-professional phagocytes in the Drosophila ovary [PDF]
, 2017 This manuscript was supported by NIH grant R01 GM060574 to KM.
McCall, Kimberly, Serizier, Sandy B.
core +1 more source
Secretion of a Differentiated Cuticle after Apolysis in vitro in Cockroach Leg Integument
, 2007 Pieces of the integument cut off from the hind tibiae of the freshly moulted adult cockroaches were cultivated in vitro. The epidermis reacted to the application of 2 x 10-5 mol l-1 ecdysterone by an apolysis.
Hassenrück, R. (Rita) +1 more
core
Anopheles gambiae blood feeding Initiates an anticipatory defense response to plasmodium berghei
, 2014 Mosquitoes have potent innate defense mechanisms that protect them from infection by diverse pathogens. Much remains unknown about how different pathogens are sensed and specific responses triggered.
Christophides, GK +2 more
core +1 more source
miR-34-5p mediates 20E-induced autophagy in the fat body of Bombyx mori by targeting Atg1
BMC GenomicsBackground 20-Hydroxyecdysone (20E) is an important hormone that regulates insect development and metamorphosis. The fat body of insects plays a crucial role in nutrient storage and energy metabolism and is considered the exchange center for regulating ...
Huili Qiao +9 more
doaj +1 more source